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RE: making steroid cream?

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First of all the heat might well render it inert. Or cause changes that

even make ti dangerous. Whne HC cream is available OTC already why

would you even try this?

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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>

> First of all the heat might well render it inert. Or cause changes that

> even make ti dangerous. Whne HC cream is available OTC already why

> would you even try this?

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

Because I don't tolerate HC and I'm dying from hashi's?

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>

> First of all the heat might well render it inert. Or cause changes that

> even make ti dangerous. Whne HC cream is available OTC already why

> would you even try this?

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

Because I don't tolerate HC and I'm dying from hashi's?

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>

> Then why not just take Medrol or Pred even?

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

Because my stomach is burning and filled with ulcers from taking it

last year and from being hypo. I can't find a doctor to Rx a

compounded medrol cream, so I don't know what options I have left. I

guess I could use the time to finish my living will while I'm still

partially coherent. :-o

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>

> Then why not just take Medrol or Pred even?

>

> --

> Artistic Grooming- Hurricane WV

>

> http://www.stopthethyroidmadness.com/

>

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

> http://health.groups.yahoo.com/group/RT3_T3/

>

Because my stomach is burning and filled with ulcers from taking it

last year and from being hypo. I can't find a doctor to Rx a

compounded medrol cream, so I don't know what options I have left. I

guess I could use the time to finish my living will while I'm still

partially coherent. :-o

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Try using the OTC hyrdorcortisone cream. You don't need a script and it is

already mixed up so you would know the dosage was correct. If you try to

make your own it might not be evenly mixed.

Rie

A positive attitude may not solve all your problems, but it will annoy

enough people to make it worth the effort. Herm Albright

>

>

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9:22 AM

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st4rcycle wrote:

> Because my stomach is burning and filled with ulcers from taking it

> last year and from being hypo. I can't find a doctor to Rx a

> compounded medrol cream, so I don't know what options I have left. I

> guess I could use the time to finish my living will while I'm still

> partially coherent. :-o

>

>

I " m confused, if you could use a compounded medrol cream, I can't see

why you couldn't use a topical 1% HC cream?

It also avoids the GI tract? Isn't that what you are after? If it is

that you don't like the inactive ingred in the OTC cream, keep in mind

you would be dosing yourself the fillers in the pred or medrol, if your

homemade topical worked (I doubt it would work, but still, you'd be

getting more in your body than just the steroid).

Can you explain more why you can't use topical HC creams? There is also

a gel product, though I forget the name of it.

sol

>

>

>

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http://www.google.com/search?client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial\

&channel=s&hl=en&q=methylprednisolone+cream&btnG=Google+Search

http://www.google.com/search?hl=en&client=firefox-a&channel=s&rls=org.mozilla%3A\

en-US%3Aofficial&hs=4zM&q=prednisone+cream&btnG=Search

See if you can find these products on our supplier's websites.

--

Artistic Grooming- Hurricane WV

http://www.stopthethyroidmadness.com/

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/

http://health.groups.yahoo.com/group/RT3_T3/

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> > Because my stomach is burning and filled with ulcers from taking it

> > last year and from being hypo. I can't find a doctor to Rx a

> > compounded medrol cream, so I don't know what options I have left. I

> > guess I could use the time to finish my living will while I'm still

> > partially coherent. :-o

> >

> >

> I " m confused, if you could use a compounded medrol cream, I can't see

> why you couldn't use a topical 1% HC cream?

> It also avoids the GI tract? Isn't that what you are after? If it is

> that you don't like the inactive ingred in the OTC cream, keep in mind

> you would be dosing yourself the fillers in the pred or medrol, if your

> homemade topical worked (I doubt it would work, but still, you'd be

> getting more in your body than just the steroid).

> Can you explain more why you can't use topical HC creams? There is also

> a gel product, though I forget the name of it.

> sol

>

When I take hydrocortisone, either orally or a cream, I descend into a

strange psychotic paranoid depression where everything feels alien

like I'm on some weird planet and all of you are robots who are

probably out to get me, where I can't think clearly and can barely

speak, and I only want to go curl up in a fetal position in a corner

somewhere and close my eyes in fear and hide. Then it wears off and

I'm back to normal again. It's always done that to me ever since being

mercury poisoned in 1998. Medrol doesn't have that effect -- I don't

even notice I'm on anything when I take medrol. I've never tried any

medrol cream, but since I tolerate the oral form I thought the chances

are good that I could take a cream.

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Thanks, interesting that HC causes that reaction and medrol doesn't,

very strange indeed.

Too bad, though, makes it much more complicated for you. I hope you can

find something.

sol

st4rcycle wrote:

> wrote:

>

>

>> I " m confused, if you could use a compounded medrol cream, I can't see

>> why you couldn't use a topical 1% HC cream?

>>

>> sol

>>

>>

>

> When I take hydrocortisone, either orally or a cream, I descend into a

> strange psychotic paranoid depression where everything feels alien

> like I'm on some weird planet and all of you are robots who are

> probably out to get me, where I can't think clearly and can barely

> speak, and I only want to go curl up in a fetal position in a corner

> somewhere and close my eyes in fear and hide. Then it wears off and

> I'm back to normal again. It's always done that to me ever since being

> mercury poisoned in 1998. Medrol doesn't have that effect -- I don't

> even notice I'm on anything when I take medrol. I've never tried any

> medrol cream, but since I tolerate the oral form I thought the chances

> are good that I could take a cream.

>

>

>

>

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You can also have cream compounded for you at a compounding pharmacy

without a prescription. It's not as cheap as buying it at Walmart,

but it will have minimal inert/inactive ingredients compared to what

you get in the commercial creams if that is what you're after.

>

> First of all the heat might well render it inert. Or cause changes that

> even make ti dangerous. Whne HC cream is available OTC already why

> would you even try this?

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Really? With a prescription active ingredient such as pred or medrol?

Doesn't seem likely, I bet they would not do medrol or pred without a

prescription.

sol

jasrich wrote:

> You can also have cream compounded for you at a compounding pharmacy

> without a prescription. It's not as cheap as buying it at Walmart,

> but it will have minimal inert/inactive ingredients compared to what

> you get in the commercial creams if that is what you're after.

>

>

>

>

>

>

>> First of all the heat might well render it inert. Or cause changes that

>> even make ti dangerous. Whne HC cream is available OTC already why

>> would you even try this?

>>

>

>

>

>

>

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>

> You can also have cream compounded for you at a compounding pharmacy

> without a prescription. It's not as cheap as buying it at Walmart,

> but it will have minimal inert/inactive ingredients compared to what

> you get in the commercial creams if that is what you're after.

>

>

>

Thanks, I am pretty sure it is a reaction from the HC itself, though.

I've tried a couple of different OTC creams (wal-mart, cortaid) and

compounded HC capsules, and the reaction is the same from all of them.

I guess there could be a shared component in the creams that's causing

it, but then it's very doubtful that the oral caps would have the same

component as the creams.

I thought the " Advantan " methylprednisolone cream might be a solution,

then I found a reference showing that the aceponate form is supposedly

highly un-bioavailable. It appears they used it specifically to reduce

systemic absorption as much as possible. Whether it's true in practice

that it doesn't absorb much I don't know, maybe that's just a

marketing thing for the benefit of the doctors and is as much b.s. as

saying the HC doesn't absorb.

So if I have to I have to, but at needing probably at least 120g/month

(1mg per gram, 4-6mg/day x 30 = 120-180g -- if absorption corresponds

to oral dosages) I'm just afraid I'll be rolling along dependent on

it, and customs will seize a shipment or something, it would get

" lost " in the mail, be delayed, etc. I wouldn't even know, it just

wouldn't show up, and then what? I'd go from full replacement doses

down to none, and it would probably literally kill me, esp. if I were

on thyroid by that time. :o

It seems like there's got to be some doctor out there somewhere who

gets it enough to have it compounded locally - I guess I'm going to

have to keep looking. Or else order months of Advantan in advance and

try to stock up on enough to last me for probably at least 6mos-year.

I'd be too nervous to try it any other way. In an emergency situation

I guess I could take some medrol tabs I have and deal with the stomach

later, but that's not a very appealing option, either.

I've also thought about trying the steroid nasal sprays. The doctors

don't seem to have a problem handing those out, and last time I was on

one of them my BP went up to 130/90 after just a day or two (which is

high for me, normally 90/60), and I got a little " wired " feeling,

couldn't sleep, etc. And it does make me a little " aggressive " kind

of, not always so pleasant. So I know I'm absorbing even that, but the

question is how to know you're getting the right dosage. I haven't

calculated it yet from the product information, if it even can be.

-Jeff

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>>It seems like there's got to be some doctor out there somewhere who

gets it enough to have it compounded locally

Do you have a compounding Pharmacy near you? You could call and ask them if

they can recommend a dr. who might compound it for you.

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I just got off the phone with the office of an " integrative " doc not

too far from here. When I asked about armour and the need for adrenal

support, they were right on board with it, telling me stories about

how the pharmacies give them a hard time because " you're the only one

who prescribes armour, " and how " no one uses that anymore, " etc.

I got an appointment for next week.

It's going to cost me big bucks out of pocket because these

" alternative " guys charge a ton and they don't do insurance... plus

the compounding... plus the drive... but I really hope this will be

the answer!

-J.

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st4rcycle wrote:

> Thanks, I am pretty sure it is a reaction from the HC itself, though.

>

>

>

> So if I have to I have to, but at needing probably at least 120g/month

> (1mg per gram, 4-6mg/day x 30 = 120-180g -- if absorption corresponds

> to oral dosages) I'm just afraid I'll be rolling along dependent on

> it, and customs will seize a shipment or something, it would get

> " lost " in the mail, be delayed, etc. I wouldn't even know, it just

> wouldn't show up, and then what? I'd go from full replacement doses

> down to none, and it would probably literally kill me, esp. if I were

> on thyroid by that time. :o

>

**I think you are quite realistic about the above. It would be entirely

appropriate to maintain enough on hand to see you through a complete

taper to zero if you had to do that from supply becoming totally

unavailable. Better safe than sorry!

> It seems like there's got to be some doctor out there somewhere who

> gets it enough to have it compounded locally - I guess I'm going to

> have to keep looking. Or else order months of Advantan in advance and

> try to stock up on enough to last me for probably at least 6mos-year.

>

Do you know or are you able to find out how long any topical remains

useable?

> I'd be too nervous to try it any other way. In an emergency situation

> I guess I could take some medrol tabs I have and deal with the stomach

> later, but that's not a very appealing option, either.

>

**I guess you tried all the standard things, taking it with food, taking

it with antacids, taking DGL or other stomach soother also. Yeah, you

must have. But this trick may help in an emergency----When I need to

take a pill dose of my HC I have been putting the pill inside an empty

capsule then putting that capsule inside another larger one. This is

supposed to retard digestion enough to prevent some of the stomach

irritation. I still take it with food though. People have used this

trick with other stomach irritating meds, and say it works, but one

pharmacist told me gel caps dissolve as soon as they hit the stomach so

he didn't see how it could work.............still................??

While I don't think this would necessarily help you long term, it might

be useful in an emergency.

I took piroxicam for months, always with food (biggest meal) with no

trouble, until the day it started eating my stomach. Took a while to

identify the cause, because I had taken it so long with no trouble I

didn't think of it being a problem suddenly. I actually thought I was

having heart attacks, but it was just very extreme stomach pain. Now, I

can only take it once or at most twice in a week, then need to be off it

for several weeks again. It is supposed to be the worst med on the

market for stomach problems, but unfortunately it is also the only pain

killer that really works for me.

The nasal sprays sound like a reasonable option if you can nail down the

dosing.

sol

> I've also thought about trying the steroid nasal sprays. The doctors

> don't seem to have a problem handing those out, and last time I was on

> one of them my BP went up to 130/90 after just a day or two (which is

> high for me, normally 90/60), and I got a little " wired " feeling,

> couldn't sleep, etc. And it does make me a little " aggressive " kind

> of, not always so pleasant. So I know I'm absorbing even that, but the

> question is how to know you're getting the right dosage. I haven't

> calculated it yet from the product information, if it even can be.

>

>

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> **I think you are quite realistic about the above. It would be entirely

> appropriate to maintain enough on hand to see you through a complete

> taper to zero if you had to do that from supply becoming totally

> unavailable. Better safe than sorry!

> > It seems like there's got to be some doctor out there somewhere who

> > gets it enough to have it compounded locally - I guess I'm going to

> > have to keep looking. Or else order months of Advantan in advance and

> > try to stock up on enough to last me for probably at least 6mos-year.

> >

> Do you know or are you able to find out how long any topical remains

> useable?

> > I'd be too nervous to try it any other way. In an emergency situation

> > I guess I could take some medrol tabs I have and deal with the stomach

> > later, but that's not a very appealing option, either.

> >

> **I guess you tried all the standard things, taking it with food,

taking

> it with antacids, taking DGL or other stomach soother also. Yeah, you

> must have. But this trick may help in an emergency----When I need to

> take a pill dose of my HC I have been putting the pill inside an empty

> capsule then putting that capsule inside another larger one. This is

> supposed to retard digestion enough to prevent some of the stomach

> irritation. I still take it with food though. People have used this

> trick with other stomach irritating meds, and say it works, but one

> pharmacist told me gel caps dissolve as soon as they hit the stomach so

> he didn't see how it could work.............still................??

> While I don't think this would necessarily help you long term, it might

> be useful in an emergency.

> I took piroxicam for months, always with food (biggest meal) with no

> trouble, until the day it started eating my stomach. Took a while to

> identify the cause, because I had taken it so long with no trouble I

> didn't think of it being a problem suddenly. I actually thought I was

> having heart attacks, but it was just very extreme stomach pain.

Now, I

> can only take it once or at most twice in a week, then need to be

off it

> for several weeks again. It is supposed to be the worst med on the

> market for stomach problems, but unfortunately it is also the only pain

> killer that really works for me.

>

> The nasal sprays sound like a reasonable option if you can nail down

the

> dosing.

> sol

Thanks for the feedback sol. I think it's something to be concerned

about, too. I feel much better about trying to exhaust my options

locally (or even in the US) before relying on overseas for something

as serious as replacement corticosteroid.

I did think of doing that capsule idea, except with the idea of

putting the pill in the cap and then filling up the rest with olive

oil. I wasn't sure though if the oil might actually make things worse.

But it seemed like it might work. I used to take fosamax for the

osteoporosis medrol caused me the first time, and I used to put that

in a capsule. Like you, I swear it made a difference even though

supposedly it is dissolved before it leaves the stomach anyway.

I've also seen research that aspirin coated with licorice prevented

ulcers from the aspirin, in animals at least. Strangely enough, DGL

now makes me worse, I have no idea what's going on with that, but I

think it has to do with the hypothyroid and possibly low cortisol --

just one more thing I hope can be resolved once I can get optimized on

thyroid. But if I were taking medrol orally now, I think I would mix

it with DGL filled up in the capsule (you'd have to " salivate " it

first) like with the olive oil idea. As gross as it might sound, I

might even try to let the DGL coating dry on it overnight, so that it

actually *was* coated and possibly gave more protection. These stomach

problems are not fun, as it seems you also know all too well.

thanks,

-J.

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>

> Hi Jeff,

> I regularly crush up HC tablets, wet powder and apply to insect bites,

> inflamation etc. It works great!

>

Interesting - I wonder if it gets absorbed systemically at all?

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