re the Duke paper and LKS

[Guest guest]

LKS should show up on EEG, and has a specific profile. (One that I believe

we would be

aware of.)

The profile of LKS from the Natl Inst. of Neurological Disorders:

What is Landau-Kleffner Syndrome?

Landau-Kleffner syndrome (LKS) is a rare, childhood neurological disorder

characterized by the sudden or gradual development of aphasia (the inability to

understand or express language) and an abnormal electro-encephalogram (EEG).

LKS affects the parts of the brain that control comprehension and speech.

The disorder usually occurs in children between the ages of 5 and 7 years.

Typically, children with LKS develop normally but then lose their language

skills

for no apparent reason. While many of the affected individuals have

seizures, some do not. The disorder is difficult to diagnose and may be

misdiagnosed

as autism, pervasive developmental disorder, hearing impairment, learning

disability, auditory/verbal processing disorder, attention deficit disorder,

mental retardation, childhood schizophrenia, or emotional/behavioral problems.

_http://www.ninds.nih.gov/disorders/landaukleffnersyndrome/landaukleffnersyndr

ome.htm_

(http://www.ninds.nih.gov/disorders/landaukleffnersyndrome/landaukleffnersyndrom\

e.htm)

I'll see if I can identify what metabolic diseases they are referring to.

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