B6 (p5p), fatigue, and hyperglycemia

[Guest guest]

Hi,

Yesterday I just started taking the p5p (prixodixal-5-phosphate,

the active form of B6) of B6 at night, as I wasn't getting dream

recall of normal (pyridoxine form) G6. In total, I took (from all

sources) 700 mg magnesium and 66 mg p5p ( " equivalent to " 100 mg B6 -

so says the package, I assume the p5p is either " stronger " of has a

different molecular weight, hence the difference of betwen the 2

amounts of the different forms). I didn't take anything else except

mB12 (methl-cobalamine, the active form of B12 as opposed to cyano-

cobalamin - about 750-1000 mg probably), and selenium (200 mg)

I do think I had more dream recall than I have before (a marker

used by " alternative physicians " of possible B6 deficiency or

pyridoxine->p5P conversion problems), although not great - but I

wouldn't expect it to be after such a short period of time if B6->p5p

conversion was the problem. The REALLY odd thing was that my blood

sugar when I got up was somewhere between 110 and 130! Usually, this

degree of hyperglyceia (relative to whay my body seem to like of

70-85) will leave me at least somewhat fatigued until I lower it, and

a number of 120 will somehow leave me fatigued until about noon even

after I lower it. But today - nothing.. Selenium and mB12 have

never had this kind of " normalizing " effect on my strange

hyperglycemic-fatigue reaction.

So this raises the question - since B6 appears to be used a lot in

the brain a bunch - could the fatigue reaction have been a B6

deficiency, that was just barely masked by having normal blood sugars

(2.5 years ago presumably before the diabetes emerged)?

Jim

[Guest guest]

I just heard about this from a friend as well. Interesting. I wonder

why we have difficulty using the less active form of B-6? Anyone know?

Thanks,

Marva

[Guest guest]

Since you're talking about B6, just thought i'd throw in my experience

last week. I'd been taking a Vital Nutrients B6+Bcomplex supplement

for the last month, which has 250mg B6 and 15mg P5P, along with the

other vitamins. I was also taking my multi (Life Guard) which if I

take 2 a day has 200mg B6...I normally only took one a day. Anyway,

i'd been noticing tingling in my hands at night...and then last week

my hands, lower arms, and feet were getting numb/tingly. Called my doc

and he said to stop the B6 as I was getting toxic doses. I'd heard

people can have these reactions over 500mg, and I was getting about

350. So, i'll stick to under 100mg from now on! But I may try the P5P

instead. Be careful of toxicity if you're taking high doses of B6 is

all I can say!

Liz

>

> I just heard about this from a friend as well. Interesting. I

wonder

> why we have difficulty using the less active form of B-6? Anyone

know?

> Thanks,

> Marva

>