Re: Advice Please

August 25, 2010

Okay, you need to start from the beginning here.

Unfortunately, I don't know what happened when you missed your dose, but I can

guarantee you didn't go hyper. maybe you got an adrenaline rush from that, I

really don't know. But weak, shaky, pounding heart, can often be adrenaline.

Truly, it would be impossible to go hyper on the dose of t3 you're on and then

missing one dose would just make you go more hypo if anything. Yes, you probably

could have just taken the missed dose as soon as you remembered because your

doses are so small anyway, it probably wouldn't have affected anthing. I'm not

sure salt helps with an adrenaline rush. Maybe someone else could help out here

as to what happened and what to do.

Unfortunately, that dose is never going to get you anywhere. You have to lower

t4 enough to get rid of rt3 and you'll never lower your t4 very much with 30 mcg

of SR t3. At worst, you will lower your own thyroid production somewhat, but you

are not taking enough SR to make up for it, so you could be even more hypo than

when you started. At best, you're just the same. You could likely just stop it

by taking 1/2 your dose for 1 week and then nothing the next. Seriously, your

dose is that small. Most docs start people at 12.5 SR a week or even 7.5 SR

twice a day and then go up by that amount every week. I don't know what your doc

is doing.

Secondly, yes, you need to make sure your adrenals are in good shape before you

attempt to truly get onto enough rt3 to clear your rt3 problem. It's good your

AM went up, but you need a full saliva panel that shows what is going on AM,

noon, 4 and night. Then post the results to the adrenal group and they'll help

you. They're very, very good.

Then you can go from there and truly get better. :-)

Kathleen

>

> Hi,

> Just a little History.

> Have RT3 and Thyroglobulin AB's ,I've been on Slow Release T3 for 5 months,

and at a dose now of 15mcg x 2 daily 6.30AM & 6.30PM, no HC Adrenal Support as

Anti-Ageing Doc only advises Adaptogens and Vitamins, and I haven't been using

the Adaptogens just lately as I'm getting confused with everything I read as to

which one is the best for me and the best time to take it.I had low cortisol in

the Am but it is now good according to Labs.

> Also been on Compounded Progesterone for a few weeks due to being Low with

Oestrogen Dominance.

>

> I know this dose of SRT3 is very low according to some here but the doc

doesn't want me to go any higher.

> I don't feel any different now to when I first started, except since taking

the Progesterone I feel I am sleeping better.

>

> To my main question,

>

> I had a bit of a scare last night, I forgot to take my morning dose of SRT3

and it was over 6 hrs later by the time I remembered, so I just took my evening

dose as usual, I was fine all day and evening, but awoke in the middle of the

night with pounding and erratic heart beat and pulse racing, with some

relaxation breathing it went away in about an hour or so, I can on only assume

this happened because I suddenly lowered the dose by forgetting the Am and by

taking the evening dose to my body it was like a larger dose and I had a HYPER

attack, does that make sense?

> Could that also mean that I am using it up quite fast,because I'm not on

enough.... so confused!

>

> If that's the case what would have been the best thing to do ??.. should I

have maybe taken a smaller dose as soon as I remembered I had missed one [i have

some 5mcg capsules]to bridge the gap?

>

> I phoned the doc this morning, but in a relayed message she said I shouldn't

be taking the 15mcg at 6.30pm....too late she say's...but I've been taking at

that time for a while and had no adverse effect before, I've even tried a 9am/

9pm schedule and it's been fine,so I know that time had nothing to do with it,

I said I was feeling O.K now just a little weak and still a bit shaky, and I had

taken my normal Am dose, and all I was told was if I felt bad to make an

appointment with a my local GP or get back to her.

> Needless to say I was not very happy with her she gave me no explanation of

what could have happened or what to do in those situations.

>

> I just would like to know what is the best thing to do if I miss again by any

chance?

> Also does the Sea Salt regulate the Heart/pulse in a HYPER situation or is

that just for Low Sodium.??

>

> Just in case I also decide to wean off the SRT3 altogether, can someone help

with the process,? I would assume that as I started with 2.5mcg and increased

every 5-7 days that this should be the case in reverse....correct??

> If I can't get anywhere on this dose I may as well not be on anything for the

thyroid and just concentrate on trying to get the adrenals in shape.

>

> Thanks

> Sandy

>

August 25, 2010

Well nothing happened when I missed the dose in the Am it was only in the middle

of the night I had this heart/pulse problem, and you are probably right about it

being an adrenaline rush.....but I can't work out what it was that made it

happen.....it's almost like my body thought I was starting from scratch and this

was like the reaction I got to just the 10mcg dose in the beginning.

Just to fill you in, when I first started SRT3 the doc had me taking 10mcg at

6am and again at about 11am after next day on this dose I started getting a

similar reaction to what I had last night, I had taken the 6am dose so rang the

doc and was instructed not to take the 11am dose which I didn't but still had

the heart pounding etc most of the day so stopped taking it altogether, after

talking with the doc a couple of weeks later started again at the lower dose of

2.5mcg x 2 and worked up from there to where I am now, just raising at 2.5mcg

each time, I can't seem to handle big raises or big doses and I Know it is

because of the adrenal glands and anxiety & stress that I have been under for so

many years, this doc seems less concerned about the adrenal side of things.

Yes I am concerned that she does not really know what she is doing, that's why I

am thinking I should just come off it altogether I just seem to be getting worse

not better......and most likely that it IS the low dose that is affecting me

adversely.

At the start I did have a Full Cortisol Saliva Test which showed Low in Am,

higher midday, over-range afternoon and high in the evening, this time she only

did an AM, I did post all my results quite some time ago.

At last test in April my TSH was 1.0mU/L (0.3 - 5.0)

Thanks

Sandy

> >

> > Hi,

> > Just a little History.

> > Have RT3 and Thyroglobulin AB's ,I've been on Slow Release T3 for 5 months,

and at a dose now of 15mcg x 2 daily 6.30AM & 6.30PM, no HC Adrenal Support as

Anti-Ageing Doc only advises Adaptogens and Vitamins, and I haven't been using

the Adaptogens just lately as I'm getting confused with everything I read as to

which one is the best for me and the best time to take it.I had low cortisol in

the Am but it is now good according to Labs.

> > Also been on Compounded Progesterone for a few weeks due to being Low with

Oestrogen Dominance.

> >

> > I know this dose of SRT3 is very low according to some here but the doc

doesn't want me to go any higher.

> > I don't feel any different now to when I first started, except since taking

the Progesterone I feel I am sleeping better.

> >

> > To my main question,

> >

> > I had a bit of a scare last night, I forgot to take my morning dose of SRT3

and it was over 6 hrs later by the time I remembered, so I just took my evening

dose as usual, I was fine all day and evening, but awoke in the middle of the

night with pounding and erratic heart beat and pulse racing, with some

relaxation breathing it went away in about an hour or so, I can on only assume

this happened because I suddenly lowered the dose by forgetting the Am and by

taking the evening dose to my body it was like a larger dose and I had a HYPER

attack, does that make sense?

> > Could that also mean that I am using it up quite fast,because I'm not on

enough.... so confused!

> >

> > If that's the case what would have been the best thing to do ??.. should I

have maybe taken a smaller dose as soon as I remembered I had missed one [i have

some 5mcg capsules]to bridge the gap?

> >

> > I phoned the doc this morning, but in a relayed message she said I shouldn't

be taking the 15mcg at 6.30pm....too late she say's...but I've been taking at

that time for a while and had no adverse effect before, I've even tried a 9am/

9pm schedule and it's been fine,so I know that time had nothing to do with it,

I said I was feeling O.K now just a little weak and still a bit shaky, and I had

taken my normal Am dose, and all I was told was if I felt bad to make an

appointment with a my local GP or get back to her.

> > Needless to say I was not very happy with her she gave me no explanation of

what could have happened or what to do in those situations.

> >

> > I just would like to know what is the best thing to do if I miss again by

any chance?

> > Also does the Sea Salt regulate the Heart/pulse in a HYPER situation or is

that just for Low Sodium.??

> >

> > Just in case I also decide to wean off the SRT3 altogether, can someone help

with the process,? I would assume that as I started with 2.5mcg and increased

every 5-7 days that this should be the case in reverse....correct??

> > If I can't get anywhere on this dose I may as well not be on anything for

the thyroid and just concentrate on trying to get the adrenals in shape.

> >

> > Thanks

> > Sandy

> >

>

August 26, 2010

Hello,

Not tolerating such tiny doses point to either low iron or low cortisol. I know

as I had such problems. I once crashed from 6 mcg t3. I had a ferritin of 20,

though.

Sometimes the adrenals seem OK until you add in the t3 (or any thyroid nmeds)

and then they can't handle it. This is true with me. My adrenals can barely keep

up with a lowered metabolism let alone a normal one. So a new full panel might

give you some useful info.

Also, Have you done an iron panel? this gives many people a ton of grief. You

need the full iron panel plus ferritin.

Kathleen

> > >

> > > Hi,

> > > Just a little History.

> > > Have RT3 and Thyroglobulin AB's ,I've been on Slow Release T3 for 5

months, and at a dose now of 15mcg x 2 daily 6.30AM & 6.30PM, no HC Adrenal

Support as Anti-Ageing Doc only advises Adaptogens and Vitamins, and I haven't

been using the Adaptogens just lately as I'm getting confused with everything I

read as to which one is the best for me and the best time to take it.I had low

cortisol in the Am but it is now good according to Labs.

> > > Also been on Compounded Progesterone for a few weeks due to being Low with

Oestrogen Dominance.

> > >

> > > I know this dose of SRT3 is very low according to some here but the doc

doesn't want me to go any higher.

> > > I don't feel any different now to when I first started, except since

taking the Progesterone I feel I am sleeping better.

> > >

> > > To my main question,

> > >

> > > I had a bit of a scare last night, I forgot to take my morning dose of

SRT3 and it was over 6 hrs later by the time I remembered, so I just took my

evening dose as usual, I was fine all day and evening, but awoke in the middle

of the night with pounding and erratic heart beat and pulse racing, with some

relaxation breathing it went away in about an hour or so, I can on only assume

this happened because I suddenly lowered the dose by forgetting the Am and by

taking the evening dose to my body it was like a larger dose and I had a HYPER

attack, does that make sense?

> > > Could that also mean that I am using it up quite fast,because I'm not on

enough.... so confused!

> > >

> > > If that's the case what would have been the best thing to do ??.. should I

have maybe taken a smaller dose as soon as I remembered I had missed one [i have

some 5mcg capsules]to bridge the gap?

> > >

> > > I phoned the doc this morning, but in a relayed message she said I

shouldn't be taking the 15mcg at 6.30pm....too late she say's...but I've been

taking at that time for a while and had no adverse effect before, I've even

tried a 9am/ 9pm schedule and it's been fine,so I know that time had nothing to

do with it, I said I was feeling O.K now just a little weak and still a bit

shaky, and I had taken my normal Am dose, and all I was told was if I felt bad

to make an appointment with a my local GP or get back to her.

> > > Needless to say I was not very happy with her she gave me no explanation

of what could have happened or what to do in those situations.

> > >

> > > I just would like to know what is the best thing to do if I miss again by

any chance?

> > > Also does the Sea Salt regulate the Heart/pulse in a HYPER situation or is

that just for Low Sodium.??

> > >

> > > Just in case I also decide to wean off the SRT3 altogether, can someone

help with the process,? I would assume that as I started with 2.5mcg and

increased every 5-7 days that this should be the case in reverse....correct??

> > > If I can't get anywhere on this dose I may as well not be on anything for

the thyroid and just concentrate on trying to get the adrenals in shape.

> > >

> > > Thanks

> > > Sandy

> > >

> >

>

August 27, 2010

Hi Kathleen,

Well I had Iron Labs done back in January

Ferritin High 175ug/L [30 - 150]

B12 970 pmol/L [>150]

Red Cell Folate 3004 nmol/L [> 900]

Last Serum Iron done back in Aug 2009 17 umol/L [7 -27] and has

ranged since 2005 between 15 to 18

I am going to ask for another test and recheck about the Ferritin when I

speak to the doc again ,appt due soon.

One thing that puzzles me is with the high ferritin, which can be a

false high because of inflammation,and I do have arthritis, but when

tested for CRP came up negative.

With the high Ferritin I am a bit worried about taking any extra Iron

supps unless I can confirm a False High, what other test could help me

confirm this.?

Hemochromatosis has been suggested but I don't think the reading is high

enough for that.

I would tend more towards the Cortisol being the problem, I have

suffered for years with anxiety/stress and seem to get what I think are

little adrenaline rushes at the slightest things, even to the point of

thinking about something stressful to me.

I did think that since there has been improvement in the morning

cortisol reading that I would be handling it a bit better, unless the

Lab test is wrong.

If I have perhaps lowered my own production of thyroid, by weaning off

the T3 in the way you suggested would this give my thyroid time to take

up the slack and start producing enough again.?

Thanks for your help

Sandy

-- In RT3_T3 , " keickholt13 " wrote:

>

> Hello,

>

> Not tolerating such tiny doses point to either low iron or low

cortisol. I know as I had such problems. I once crashed from 6 mcg t3. I

had a ferritin of 20, though.

>

> Sometimes the adrenals seem OK until you add in the t3 (or any thyroid

nmeds) and then they can't handle it. This is true with me. My adrenals

can barely keep up with a lowered metabolism let alone a normal one. So

a new full panel might give you some useful info.

>

> Also, Have you done an iron panel? this gives many people a ton of

grief. You need the full iron panel plus ferritin.

>

> Kathleen

>

> > >

> > > Okay, you need to start from the beginning here.

> > >

> > > Unfortunately, I don't know what happened when you missed your

dose, but I can guarantee you didn't go hyper. maybe you got an

adrenaline rush from that, I really don't know. But weak, shaky,

pounding heart, can often be adrenaline. Truly, it would be impossible

to go hyper on the dose of t3 you're on and then missing one dose would

just make you go more hypo if anything. Yes, you probably could have

just taken the missed dose as soon as you remembered because your doses

are so small anyway, it probably wouldn't have affected anthing. I'm not

sure salt helps with an adrenaline rush. Maybe someone else could help

out here as to what happened and what to do.

> > >

> > > Unfortunately, that dose is never going to get you anywhere. You

have to lower t4 enough to get rid of rt3 and you'll never lower your t4

very much with 30 mcg of SR t3. At worst, you will lower your own

thyroid production somewhat, but you are not taking enough SR to make up

for it, so you could be even more hypo than when you started. At best,

you're just the same. You could likely just stop it by taking 1/2 your

dose for 1 week and then nothing the next. Seriously, your dose is that

small. Most docs start people at 12.5 SR a week or even 7.5 SR twice a

day and then go up by that amount every week. I don't know what your doc

is doing.

> > >

> > > Secondly, yes, you need to make sure your adrenals are in good

shape before you attempt to truly get onto enough rt3 to clear your rt3

problem. It's good your AM went up, but you need a full saliva panel

that shows what is going on AM, noon, 4 and night. Then post the results

to the adrenal group and they'll help you. They're very, very good.

> > >

> > > Then you can go from there and truly get better. :-)

> > >

> > > Kathleen

> > >

> > > --

August 27, 2010

I'm not Kathleen, but I can answer the ferritin question: I had a false-high

ferritin of 80. We now recommend an iron panel test, with a result of %

saturation. % saturation is supposed to be 35-45 for best thyroid utilization.

Mine was 22. So despite an apparently good ferritin of 80 I was still too low

in iron.

(I also have inflammation, but my CRP is ALWAYS negative. I think there are

types of inflammation the CRP does not detect.)

> > > >

> > > > Okay, you need to start from the beginning here.

> > > >

> > > > Unfortunately, I don't know what happened when you missed your

> dose, but I can guarantee you didn't go hyper. maybe you got an

> adrenaline rush from that, I really don't know. But weak, shaky,

> pounding heart, can often be adrenaline. Truly, it would be impossible

> to go hyper on the dose of t3 you're on and then missing one dose would

> just make you go more hypo if anything. Yes, you probably could have

> just taken the missed dose as soon as you remembered because your doses

> are so small anyway, it probably wouldn't have affected anthing. I'm not

> sure salt helps with an adrenaline rush. Maybe someone else could help

> out here as to what happened and what to do.

> > > >

> > > > Unfortunately, that dose is never going to get you anywhere. You

> have to lower t4 enough to get rid of rt3 and you'll never lower your t4

> very much with 30 mcg of SR t3. At worst, you will lower your own

> thyroid production somewhat, but you are not taking enough SR to make up

> for it, so you could be even more hypo than when you started. At best,

> you're just the same. You could likely just stop it by taking 1/2 your

> dose for 1 week and then nothing the next. Seriously, your dose is that

> small. Most docs start people at 12.5 SR a week or even 7.5 SR twice a

> day and then go up by that amount every week. I don't know what your doc

> is doing.

> > > >

> > > > Secondly, yes, you need to make sure your adrenals are in good

> shape before you attempt to truly get onto enough rt3 to clear your rt3

> problem. It's good your AM went up, but you need a full saliva panel

> that shows what is going on AM, noon, 4 and night. Then post the results

> to the adrenal group and they'll help you. They're very, very good.

> > > >

> > > > Then you can go from there and truly get better. :-)

> > > >

> > > > Kathleen

> > > >

> > > > --

>

August 27, 2010

what types of inflammation does crp detect..my brother in law just had his ferritin tested (but no panel unfortunately)..and his crp was like 10....so we are redoing the iron panel but i am wondering if crp is specific for certain types of inflammation?

Subject: Re: Advice PleaseTo: RT3_T3 Date: Friday, August 27, 2010, 8:35 AM

I'm not Kathleen, but I can answer the ferritin question: I had a false-high ferritin of 80. We now recommend an iron panel test, with a result of % saturation. % saturation is supposed to be 35-45 for best thyroid utilization. Mine was 22. So despite an apparently good ferritin of 80 I was still too low in iron.(I also have inflammation, but my CRP is ALWAYS negative. I think there are types of inflammation the CRP does not detect.) > > > >> > > > Okay, you need to start from the beginning here.> > > >> > > > Unfortunately, I don't know what happened when you missed your> dose, but I can guarantee you didn't go hyper. maybe you got an> adrenaline rush from that, I really don't know. But weak, shaky,> pounding heart, can often be adrenaline. Truly, it would be impossible> to go hyper on the dose of t3 you're on and then missing one dose would> just make you go more hypo if anything. Yes, you probably could have> just taken the missed dose as soon as you remembered because your doses> are so small anyway,

it probably wouldn't have affected anthing. I'm not> sure salt helps with an adrenaline rush. Maybe someone else could help> out here as to what happened and what to do.> > > >> > > > Unfortunately, that dose is never going to get you anywhere. You> have to lower t4 enough to get rid of rt3 and you'll never lower your t4> very much with 30 mcg of SR t3. At worst, you will lower your own> thyroid production somewhat, but you are not taking enough SR to make up> for it, so you could be even more hypo than when you started. At best,> you're just the same. You could likely just stop it by taking 1/2 your> dose for 1 week and then nothing the next. Seriously, your dose is that> small. Most docs start people at 12.5 SR a week or even 7.5 SR twice a> day and then go up by that amount every week. I don't know what your doc> is doing.> > >

>> > > > Secondly, yes, you need to make sure your adrenals are in good> shape before you attempt to truly get onto enough rt3 to clear your rt3> problem. It's good your AM went up, but you need a full saliva panel> that shows what is going on AM, noon, 4 and night. Then post the results> to the adrenal group and they'll help you. They're very, very good.> > > >> > > > Then you can go from there and truly get better. :-)> > > >> > > > Kathleen> > > >> > > > -->

August 27, 2010

Unfortunately, you need a full iron panel which icludes the serum iron and Total

Iron Binding Capacity (TIBC) as you are correct that ferritin can look falsely

high from inflammation. And apparetnly when people have low cortisol they often

have a lot of inflammation. So

Feritin alone doesn't give a complete picture. :-( Also, we are supposed to stop

any iron supps for 5 days and not eat red meat during that time either. The TIBC

and % saturation (which the lab will compute for you) shows whether your body is

capable of binding more iron. If that is high, then your body wants and needs

more iron.

About the inflammation markers, Margery told me she had tons of inflammation

going on in her body, joints I think, and her inflammation markers came up

normal, too! So maybe those tests aren't as accurate as they'd have us believe.

I used to have a pattern of almost normal AM cortisol and way too low noon, so

yes, your pattern could have changed and you still have low cortisol going on.

You really need to do another panel if you ever hope to tolerate thyroid meds.

For weaning off, don't worry, your dose is low enough, you can safely wean off

as I suggested, 15 mcg a day. IF you are uncomfortble with that, you can go

slower, it won't hurt, and yes, your own thyroid will come back usually within

in 2 weeks both from what I've read and based on my own experience as I've had

to stop thyroid many times in the past.