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Re: Val-apology / cortisol binding globulin (CBG)

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Perhaps having CBG tested would provide useful info. My own CBG was high (61 in

a range of 19 to 45). I understood this to mean that a lot of the HC I was

taking was being bound up into an unusable form, rather than being properly

utilized. I did take more HC to compensate.

My own CBG changed over time, though, and it has happened that last month's

" correct " HC dose turned into this month's " too-high " HC dose. It is

unfortunately an ongoing project to figure my correct HC dose.

> > Val i apologise if i offended in my last post. I mis interpreted your

capitals and was too quick to jump down your throat. So i am sorry.

> >

> > I hope you can help me with pretty much the biggest problem that is holding

me back...

> >

> > What is causing optimal/high cortisol in my blood but low FREE cortisol as

was evident in my saliva labs. Thus resulting in RT3..

> >

> > Blood - 624 (200-600)

> > Urine - 85 (20-120)

> > Saliva - 15 (6-45)

> > - 3.8 (0-15)

> > - 2.8 (0-10)

> > - 2.8 (0-5)

> >

> > I need your advice here. I tried 6.25mcg of T3 once per day and experienced

light headedness, hypoglycemic episodes and felt worse. So obviously Low

cortisol sounds like the problem.

> >

> > I tried 30mg of HC a few months back and i had no reliance on it.. and the

higher i got.. the hotter i felt almost intolerably hot. Overall i felt really

bad on 30mg and when i dropped the HC i felt better.. You saw my Urine result

and said to try adaptogens but i just feel they probably won't be enough

considering my reaction to only 6.25mcg of Cytomel... Do you think i should try

a larger dose of HC? Would this overcome the likely problem of high CBG??

> >

> > I would gratefuly if you could guide me on this one.

> >

> > Thankyou

> >

> >

> >

> > ------------------------------------

> >

> > We are not medical professionals here, just patients sharing our

experiences. Please use this information with the help of a competent doctor.

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Thanks, still want to try HC one more time.. i can't get my hands on Medrol from

my doctor.. he only prescribes HC or prednisone i think.

My next plan of attack is to try a high dose upwards of 40mg HC and see how that

goes. The 30 wasn't enough and i know you said many men need over 40 so

hopefully this gets the job done.

I'm assuming there are many people on here with a cortisol resistance like

problem with high CBG.. and they probably take more HC to compensate.. hey if it

works then great.

Margery, well i take your experience as a positive. The fact that you can lower

CBG is promising. I read on some older posts in the NTH Adrenals forum that

hypothyroidism can cause CBG and that when you become unhypo the CBG normalises.

Hopefully this is true.

What i know is that SOME cortisol is getting through i just need more.. so i

guess a HIGH dose HC will have to do the trick.. if not Medrol.

> > > Val i apologise if i offended in my last post. I mis interpreted your

capitals and was too quick to jump down your throat. So i am sorry.

> > >

> > > I hope you can help me with pretty much the biggest problem that is

holding me back...

> > >

> > > What is causing optimal/high cortisol in my blood but low FREE cortisol as

was evident in my saliva labs. Thus resulting in RT3..

> > >

> > > Blood - 624 (200-600)

> > > Urine - 85 (20-120)

> > > Saliva - 15 (6-45)

> > > - 3.8 (0-15)

> > > - 2.8 (0-10)

> > > - 2.8 (0-5)

> > >

> > > I need your advice here. I tried 6.25mcg of T3 once per day and

experienced light headedness, hypoglycemic episodes and felt worse. So obviously

Low cortisol sounds like the problem.

> > >

> > > I tried 30mg of HC a few months back and i had no reliance on it.. and the

higher i got.. the hotter i felt almost intolerably hot. Overall i felt really

bad on 30mg and when i dropped the HC i felt better.. You saw my Urine result

and said to try adaptogens but i just feel they probably won't be enough

considering my reaction to only 6.25mcg of Cytomel... Do you think i should try

a larger dose of HC? Would this overcome the likely problem of high CBG??

> > >

> > > I would gratefuly if you could guide me on this one.

> > >

> > > Thankyou

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > > We are not medical professionals here, just patients sharing our

experiences. Please use this information with the help of a competent doctor.

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Guest guest

Yes, my high CBG went down. I can't say with scientific certainty why, but it

was higher when I was more hypo, lower when I was less hypo.

I'm glad you're also reading on the Adrenals group, (this is a subject there

doesn't seem to be a whole lot of information about anywhere), but there are

more posts and info at the Adrenals group about this than there are here on the

RT3 group.

> > > > Val i apologise if i offended in my last post. I mis interpreted your

capitals and was too quick to jump down your throat. So i am sorry.

> > > >

> > > > I hope you can help me with pretty much the biggest problem that is

holding me back...

> > > >

> > > > What is causing optimal/high cortisol in my blood but low FREE cortisol

as was evident in my saliva labs. Thus resulting in RT3..

> > > >

> > > > Blood - 624 (200-600)

> > > > Urine - 85 (20-120)

> > > > Saliva - 15 (6-45)

> > > > - 3.8 (0-15)

> > > > - 2.8 (0-10)

> > > > - 2.8 (0-5)

> > > >

> > > > I need your advice here. I tried 6.25mcg of T3 once per day and

experienced light headedness, hypoglycemic episodes and felt worse. So obviously

Low cortisol sounds like the problem.

> > > >

> > > > I tried 30mg of HC a few months back and i had no reliance on it.. and

the higher i got.. the hotter i felt almost intolerably hot. Overall i felt

really bad on 30mg and when i dropped the HC i felt better.. You saw my Urine

result and said to try adaptogens but i just feel they probably won't be enough

considering my reaction to only 6.25mcg of Cytomel... Do you think i should try

a larger dose of HC? Would this overcome the likely problem of high CBG??

> > > >

> > > > I would gratefuly if you could guide me on this one.

> > > >

> > > > Thankyou

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > > We are not medical professionals here, just patients sharing our

experiences. Please use this information with the help of a competent doctor.

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