Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 Hi : I have better luck with 5 times a day dosing than with 4 times a day. (I hope in time as my adrenals heal that I will be able to change to 4 times a day.) You'd mentioned that the cynomel wasn't as " smooth " as the SRT3; my own experience is that it's " smoother " with the 5x/day dosing. I take my cynomel sublingually so don't have to worry about it interacting with other pills, and it can be taken with or without food, so it's really not too much hassle to just pop one under my tongue every 4-5 hours over the day. Hope this helps. > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > My FT3/RT3 ratio is 10.82 > > > > Wayne > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I take 25mg HC also. What are your times. 7am,11,3,7,bed? I'm dosing 7am 12.5,noon 12.5, 5pm 12.5, 10:30p 12.5. Had to cut back d/t increase heart rate in the middle of the night. I'm still hypo though so I don't know. My temps were stable at 98.1- 98.3 I'm going to try and increase again. Thanks Christie > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I take 25mg HC also. What are your times. 7am,11,3,7,bed? I'm dosing 7am 12.5,noon 12.5, 5pm 12.5, 10:30p 12.5. Had to cut back d/t increase heart rate in the middle of the night. I'm still hypo though so I don't know. My temps were stable at 98.1- 98.3 I'm going to try and increase again. Thanks Christie > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I take 25mg HC also. What are your times. 7am,11,3,7,bed? I'm dosing 7am 12.5,noon 12.5, 5pm 12.5, 10:30p 12.5. Had to cut back d/t increase heart rate in the middle of the night. I'm still hypo though so I don't know. My temps were stable at 98.1- 98.3 I'm going to try and increase again. Thanks Christie > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I keep hearing about people saying they take their cytomel sublingually. The generic I have does not dissolve. The best I could do is to crunch it up to dust with my teeth and then hold it in my mouth for a while before swallowing. Is that what people here are talking about? > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I keep hearing about people saying they take their cytomel sublingually. The generic I have does not dissolve. The best I could do is to crunch it up to dust with my teeth and then hold it in my mouth for a while before swallowing. Is that what people here are talking about? > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 I keep hearing about people saying they take their cytomel sublingually. The generic I have does not dissolve. The best I could do is to crunch it up to dust with my teeth and then hold it in my mouth for a while before swallowing. Is that what people here are talking about? > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 what is it that cause a speed up in heart rate and feeling sweaty and hot ...for me it usually just last a few minutes then goes away on its own....seems to happen at different times unrelated to when i take my meds or isocort....i am 51 and on some biest but how can i tell if it is a hot flash or adrenal or too much thyroid med?? i mean what seperates it from hyperthyroid or adrenal? Subject: Re: Slow Release T3 success? /5x/day dosingTo: RT3_T3 Date: Thursday, August 5, 2010, 4:34 PM I keep hearing about people saying they take their cytomel sublingually. The generic I have does not dissolve. The best I could do is to crunch it up to dust with my teeth and then hold it in my mouth for a while before swallowing. Is that what people here are talking about?> > > > >> > > > > Who amongst us here has used "Slow Release T3" and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great.> > > > > My FT3/RT3 ratio is 10.82> > > > > Wayne> > > > >> > > >> > >> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 5, 2010 Report Share Posted August 5, 2010 Yes, some brands just don't want to dissolve. When I had the hard ones, I crunched 'em up a little with my teeth and just let the crumbs sit under my tongue until they finally dissolved. > > > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > > My FT3/RT3 ratio is 10.82 > > > > > > Wayne > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 6, 2010 Report Share Posted August 6, 2010 Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the > >experiences and outcomes? The reason I pose the question is that both my > >Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as > >the way to go. So any feedback would be great. > > > > > My FT3/RT3 ratio is 10.82 > > > > > Wayne > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 6, 2010 Report Share Posted August 6, 2010 Hi Christie: Here's my dosing for T3 and HC: T3 five even doses, taken sublingually: When I wake up, then about every 3 1/2 to 4 hours after that. HC Since I have to take it with food, I take it with meals. Here's an example from when I was on 30 mg/day: Breakfast 10 Lunch 7.5 Dinner 7.5 Bedtime 5.0 This worked will for me. It will not be ideal for everyone. For example, some people can't sleep when they take a bedtime HC dose. But I find it helps my own sleep. Hope this helps. > > > > > > > > > > > > Who amongst us here has used " Slow Release T3 " and what have been the experiences and outcomes? The reason I pose the question is that both my Naturopath and my Compounding Pharmacist are both strongly suggesting SRT3 as the way to go. So any feedback would be great. > > > > > > My FT3/RT3 ratio is 10.82 > > > > > > Wayne > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 6, 2010 Report Share Posted August 6, 2010 Two things: First, are people really sure this is true sublingual absorption? I think something has to be specially formulated to be absorbed sublingually. I chew mine and sort of get it under my tongue, but my guess is it's ultimately ending up being absorbed in my stomach. Second, I literally have to take cynomel every 3 hours (even in the middle of the night) or I start to get a horrible rebound headache. From a previous discussion, I take it that I'm a rapid adapter. No way I can stay on the same dose for 3 days. I have to go up daily (as described) and when I get to a dose where a further increase causes me to feel shakey, I'm stuck as I'll get headaches if I go down. Would be interested to hear if mods think something else is going on. > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 2010 Report Share Posted August 8, 2010 I don't know of any studies proving " true sublingual absorption " , but we do have many group members taking sublingual T3 with very good results. The T3 results are good even if the T3 is taken at the same time as iron (the iron is swallowed). If the absorption of T3 was primarily in the stomach, the T3 results would be poor, as the iron would impair T3 absorption in the stomach. On your second question, most people who have problems with their T3 dosing and/or T3 intolerances have either low or high cortisol or low iron. Cortisol/Adrenal info here at Moderator Nick's excellent web page: http://www.thyroid-rt3.com/adrenals.htm Iron lab targets for best thyroid utilization are ferritin of 70-90 and % saturation of 35-45. Be sure to avoid all iron supplements for at least 5 days prior to any iron labs. Hope this helps. > > > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 2010 Report Share Posted August 8, 2010 unfortunately, I have to wonder about the absorption sublinqually as well or whether it's just mixing with your saliva and going down your throat. If you're taking Ferochel iron (in Bluebonnet, for example) the iron wouldn't bind the t3 anyway because Ferrochel is molecularly chelated to the iron and does not ionize in the gut, thus, cannot attach to anything, including the t3 you just took. I know when I took my t3 sublinqually, my labs looked a lot different than they do now on the same exact dose. So for me at least, it just seems it wasn't absorbing as well as swallowing it, but I know others here do sublinqual and say it works fine. Maybe they end up on a higher dose ultimately; I have no idea. Kathleen > > > > > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > > > > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 2010 Report Share Posted August 8, 2010 unfortunately, I have to wonder about the absorption sublinqually as well or whether it's just mixing with your saliva and going down your throat. If you're taking Ferochel iron (in Bluebonnet, for example) the iron wouldn't bind the t3 anyway because Ferrochel is molecularly chelated to the iron and does not ionize in the gut, thus, cannot attach to anything, including the t3 you just took. I know when I took my t3 sublinqually, my labs looked a lot different than they do now on the same exact dose. So for me at least, it just seems it wasn't absorbing as well as swallowing it, but I know others here do sublinqual and say it works fine. Maybe they end up on a higher dose ultimately; I have no idea. Kathleen > > > > > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > > > > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 2010 Report Share Posted August 8, 2010 unfortunately, I have to wonder about the absorption sublinqually as well or whether it's just mixing with your saliva and going down your throat. If you're taking Ferochel iron (in Bluebonnet, for example) the iron wouldn't bind the t3 anyway because Ferrochel is molecularly chelated to the iron and does not ionize in the gut, thus, cannot attach to anything, including the t3 you just took. I know when I took my t3 sublinqually, my labs looked a lot different than they do now on the same exact dose. So for me at least, it just seems it wasn't absorbing as well as swallowing it, but I know others here do sublinqual and say it works fine. Maybe they end up on a higher dose ultimately; I have no idea. Kathleen > > > > > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > > > > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 2010 Report Share Posted August 8, 2010 Hi Kathleen: this is a puzzle, as any T3 not absorbed sublingually would be, as you say, simply swallowed eventually and absorbed in the stomach. The dosage delivered to the body should be the same, whatever route it is taking. I understood that taking T3 sublingually avoided interaction not only with iron, but with calcium as well. My labs looked exactly the same whether I swallowed the T3 or took it sublingually. I take it sublingually now mainly to avoid stomach interactions with calcium, etc., and also because I have trouble absorbing anything I swallow. The useful thing to take away from this, I think, is again that not one way works best for everyone. Anyone having less than ideal results swallowing T3 might wish to try try sublingual administration. The reverse would also be true; if sublingual doesn't seem to be well-absorbed, it is certainly worth trying swallowing the T3. > > > > > > > > Any T3 EXCEPT SUSTAINED RELEASE (SRT3) can be taken sublingually. I take the Cynomel made by Grossman, it dissolves quickly and has almost no flavor. Some brands take longer to dissolve than others (I had one US-made T3 that was hard as a rock!) but they all dissolve sublingually, eventually. > > > > > > > > SRT3 can NOT be taken sublingually, it might cause problems with the timing of the sustained-release process. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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