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Surgery CJD

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Friday, February 26,

1999 Published at 01:44 GMT

Health

CJD warning over surgery

Surgical operations could

be linked to sporadic CJD

Routine surgical operations

could be linked to a form of

Creutzfeldt-Jakob Disease

(CJD).

Australian researchers

studying the risk factors linked to

sporadic CJD have found

that the greatest is surgery for

conditions like

hysterectomies and heart surgery.

They think

their findings could have

implications

for " new variant CJD "

caused by

eating beef infected with

bovine

spongiform encephalopathy

(BSE).

CJD - a

degenerative, fatal brain

disorder that

leads to progressive

dementia and

other conditions -

comes in several forms. The

most common is sporadic

CJD that mainly affects

elderly people and accounts for

between 85 and 95% of cases

worldwide.

Risk factors

Scientists do not know what

causes it, but researchers

from the Australian

National Creutzfeldt-Jakob Disease

Registry sought to isolate

some risk factors.

They

studied 241 definite and

probable cases of CJD and

compared them with 784

healthy

volunteers.

The

information on the CJD

cases

came from the

registry's records of cases

between

1970 and 1993.

The

greatest risk factor was

for

people who had had three

or more

operations, including

hysterectomies, heart

surgery, haemorrhoid

removal, cataracts,

varicose veins and carpel tunnel

syndrome.

But people who had organ

transplants, blood

transfusions and major

dental work were at no increased

risk.

Other risk factors included

living or working on a farm or

in a market garden for more

than 10 years.

However, people who worked

in butchers shops or

abattoirs were not at any

greater risk.

Hospital infection

The researchers say their

findings suggest that CJD

could be linked to

infections transmitted during

operations.

Writing in the Lancet, they

say they shoud " reinforce the

heightened vigilance about

infection control at all levels

of care in hospital

settings " .

Last year, there were some

39 cases of sporadic CJD in

the UK and 12 cases of new

variant CJD.

Recent UK research has

suggested a link between new

variant CJD and surgical

instruments.

Some doctors have called

for the introduction of

disposable instruments to

prevent infection being spread.

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