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Re: Roussey-Levi Syndrome

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Roussy Levy Syndrome

Roussy-Levy Syndrome, also known as hereditary areflexic dystasia, is a rare

genetic neuromuscular disorder that typically becomes apparent during early

childhood. The disorder is characterized by incoordination, poor judgment of

movements (sensory ataxia), and absence of reflexes (areflexia) of the lower

legs and, eventually, the hands; weakness and degeneration (atrophy) of

muscles of the lower legs; abnormally high arches of the feet with increased

extension of the toes (pes cavus or " clawfoot " ); and tremors of the hands.

Many affected individuals also have an abnormal front-to-back and sideways

curvature of the spine (kyphoscoliosis). In individuals with Roussy-Levy

Syndrome, there is a failed communication of certain nerve signals to muscles

of the lower legs (denervation). Roussy-Levy Syndrome is inherited as an

autosomal dominant genetic trait.

http://www.napcosa.co.za/wheel/rlsynd.htm " >Roussy Levy Syndrome and

Muscular Dystrophy Ass…

http://www.napcosa.co.za/wheel/rlsynd.htm

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