Guest guest Posted May 27, 2000 Report Share Posted May 27, 2000 << vasculitis >> http://fohweb.macarthur.uws.edu.au/podiatry/vasculit.htm Definition Vasculitis is an inflammation of the blood vessels. Vasculitis is also defined as a pathological process centred primarily on blood walls (mainly small and medium-sized vessels) resulting in purpura, nodules and ulceration. (8) .... Treatment/Management In some cases, most notably a hypersensitivity reaction can be managed by identifying and eliminating the offending antigen or agent. However, some hypersensitivity vasculitis may also require corticosteroid treatment even after the offending antigen is eliminated. If no offending agent can be identified, other management approaches are necessary. (3, 7, 11) Vasculitis may be also associated with a primary illness, including rheumatic and connective tissue diseases, cancer, infectious diseases, and inflammatory bowel disease. In these cases the vasculitis often improves when the primary disease is treated. (3, 11) Many cases of vasculitis do not require treatment. For example, a few spots on the skin now and then (if not combined with other symptoms) may not require any cortisone-type medications. But a patient may need bed rest and some supportive measures to relieve pruritus and pain. (6, 7) The patients with only cutaneous vasculitis can be treated with dapsone. On the other hand, the instances in which vasculitis with any other diseases may be treated with short courses of prednisone, prednisolone, or methylprednisolone. In severe cases, some sort of cytotoxic drugs, such as cyclophosphamide or azathioprine are used. They are usually used in combination with prednisone and are often effective in treating vasculitis. (3, 5, 6, 11) More: http://www.aafp.org/afp/991001ap/1421.html Kat Quote Link to comment Share on other sites More sharing options...
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