Guest guest Posted April 4, 1999 Report Share Posted April 4, 1999 I have been on anti-depressants for many years, longer than I have had RLS. I have also been on anti-anxiety drugs, such as Xanax and Trazadone. The only medication that really seemed to affect my legs was Trazadone, and that was to make it worse. I can't recall if any of the other meds affected my legs, either positively or negatively. I have been on Prozac, Serzone, Effexor, Wellbutrin, Remeron, Paxil, Zoloft, Xanax, Buspar, Risperdal, Trazadone, as well as a couple of anti-psychotics since I had a nervous breakdown 3 yrs. ago. Other than the Trazadone, I haven't been able to pinpoint anything that makes my legs better or worse. Just my 2cents worth. Juli Quote Link to comment Share on other sites More sharing options...
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