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Hi all:

I thought I'd stun everyone and ask an RLS-related question . A while

back, Dr. Levin indicated that Sinemet didn't typically rebound or

augment on individuals who limited their intake to (I think) 300 mg. per

day. Here's my question: Has rebound or augmentation occurred in anyone

who actually followed this limitation?

Thanks,

Hal

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Hi Hal and all, I was on Sinemet for about 6 mnths, then I got more and more

daytime rls.

I stopped, took something else for 4 mnths, then Sinemet again, worked well, I

went on Permax

before Sinemet lost its effectiveness, my plan is take Sinemet and Permax

4 mnths each then change, so I can live happily ever after and avoid the

problems

of using a med too long.

I never took more than 50/200 mg. Sinemet a day, and always in 2 portions, 9 pm

and 2 am. Does

this answer your question Hal? Marleen,52,pushing 53, Holland

Hal White wrote:

>

>

> Hi all:

>

> I thought I'd stun everyone and ask an RLS-related question . A while

> back, Dr. Levin indicated that Sinemet didn't typically rebound or

> augment on individuals who limited their intake to (I think) 300 mg. per

> day. Here's my question: Has rebound or augmentation occurred in anyone

> who actually followed this limitation?

>

> Thanks,

> Hal

>

> ___________________________________________________________________

> You don't need to buy Internet access to use free Internet e-mail.

> Get completely free e-mail from Juno at http://www.juno.com/getjuno.html

> or call Juno at (800) 654-JUNO [654-5866]

>

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> New hobbies? New curiosities? New enthusiasms?

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> This forum is for support only. The information posted to this List is for

support purposes

> and is not intended to replace the examination, diagnosis and treatment of a

licensed

> physician and no such claims are inferred.

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In a message dated 3/4/99 6:39:47 PM !!!First Boot!!!, Serdikof@...

writes:

<< I for one had severe rebound and augmentation when taking one Sinemet CR

25/100 tablet at bedtime. This occurred after only one week. My

neurologist said that this was very rare (I'm not sure that he totally

believed me.) >>

I still don't understand why neurologists are still prescribing Sinemet for

RLS.

It has been well documented that rebound & augmentation is not a question with

Sinemet but just a matter of time.

RAINBOWPED@...

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Hal,

I for one had severe rebound and augmentation when taking one Sinemet CR

25/100 tablet at bedtime. This occurred after only one week. My

neurologist said that this was very rare (I'm not sure that he totally

believed me.) I am now taking Mirapex .25mg with great success. Some

problems with daytime rls, but nothing I can't handle. I hope this helps.

Kathy, 56, PA

Sinemet dosage

>

>

>Hi all:

>

>I thought I'd stun everyone and ask an RLS-related question . A while

>back, Dr. Levin indicated that Sinemet didn't typically rebound or

>augment on individuals who limited their intake to (I think) 300 mg. per

>day. Here's my question: Has rebound or augmentation occurred in anyone

>who actually followed this limitation?

>

>Thanks,

>Hal

>

>___________________________________________________________________

>You don't need to buy Internet access to use free Internet e-mail.

>Get completely free e-mail from Juno at http://www.juno.com/getjuno.html

>or call Juno at (800) 654-JUNO [654-5866]

>

>------------------------------------------------------------------------

>New hobbies? New curiosities? New enthusiasms?

>http://www.onelist.com

>Sign up for a new email list today

>------------------------------------------------------------------------

>This forum is for support only. The information posted to this List is for

support purposes

>and is not intended to replace the examination, diagnosis and treatment of

a licensed

>physician and no such claims are inferred.

>

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Yes. I was taking 75/300 per day and I had severe rebound and

augmention after about 6 months.

--, 52, snowbound in western NY state

---Hal White halwhite@...> wrote:

>

>

>

> Hi all:

>

> I thought I'd stun everyone and ask an RLS-related question . A

while

> back, Dr. Levin indicated that Sinemet didn't typically rebound or

> augment on individuals who limited their intake to (I think) 300 mg.

per

> day. Here's my question: Has rebound or augmentation occurred in

anyone

> who actually followed this limitation?

>

> Thanks,

> Hal

>

> ___________________________________________________________________

> You don't need to buy Internet access to use free Internet e-mail.

> Get completely free e-mail from Juno at

http://www.juno.com/getjuno.html

> or call Juno at (800) 654-JUNO [654-5866]

>

>

------------------------------------------------------------------------

> New hobbies? New curiosities? New enthusiasms?

> http://www.onelist.com

> Sign up for a new email list today

>

------------------------------------------------------------------------

> This forum is for support only. The information posted to this List

is for support purposes

> and is not intended to replace the examination, diagnosis and

treatment of a licensed

> physician and no such claims are inferred.

>

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>day. Here's my question: Has rebound or augmentation occurred in anyone

>who actually followed this limitation?

Hi Hal,

I can't ever keep the two terms straight, so let me just tell you my

experience! :) I've been on Sinemet since last summer, and I take 100mg a

couple of hours before bed and then another 100mg during the night when I

wake up. (I also take .25mg Klonopin with the earlier dose.) This regimen

worked fine for me until the last month or so. I don't have much of a

problem during the day, but then I wouldn't really notice anyway because

typically I am free during the day to move any time I want to. My problem

is at night. It has become apparent that this Klon and Sin mix is no longer

working effectively. I'm back into the annoying groove of taking 2-3 hours

to fall asleep. And the thing that is really kinda strange is that just as

I finally get sleepy and start to drift off, I suddenly have an almost

electrical kind of sensation that encompasses my entire body. I have always

just had the RLS in my legs, so this is a realy weird feeling and not a

pleasant one. I literally feel like I am going to jump out of my skin! The

good news, though, is that if I can ride it out, this intense attack will

abate within 20-30 minutes. Then my body will just as suddenly relax and

off I go to la-la land.

OK, that's my 2 cents worth! Take care.

, Atlanta

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>day. Here's my question: Has rebound or augmentation occurred in anyone

>who actually followed this limitation?

Hi Hal,

I can't ever keep the two terms straight, so let me just tell you my

experience! :) I've been on Sinemet since last summer, and I take 100mg a

couple of hours before bed and then another 100mg during the night when I

wake up. (I also take .25mg Klonopin with the earlier dose.) This regimen

worked fine for me until the last month or so. I don't have much of a

problem during the day, but then I wouldn't really notice anyway because

typically I am free during the day to move any time I want to. My problem

is at night. It has become apparent that this Klon and Sin mix is no longer

working effectively. I'm back into the annoying groove of taking 2-3 hours

to fall asleep. And the thing that is really kinda strange is that just as

I finally get sleepy and start to drift off, I suddenly have an almost

electrical kind of sensation that encompasses my entire body. I have always

just had the RLS in my legs, so this is a realy weird feeling and not a

pleasant one. I literally feel like I am going to jump out of my skin! The

good news, though, is that if I can ride it out, this intense attack will

abate within 20-30 minutes. Then my body will just as suddenly relax and

off I go to la-la land.

OK, that's my 2 cents worth! Take care.

, Atlanta

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