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Re: Celebrex

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Hi and All,

When you first mentioned Celebrex, I looked it up in a site called

askjeeves.com, and it said basically the same thing as the cox2facts.com

, EXCEPT, that it didn't point out that this 2 has fewer

gastrointestinal side effects than 1. I find that interesting, as the

askjeeves site is not promoting anything, and obviously the Tylenol

report is. Despite this, the cox2 report, although down playing this

benefit, did at least mention it.

Both sound like long term use is not ideal. BTW, I find that Alleve is

very helpful for RLS, but again, I'm sure daily use is not good, although

I haven't researched it yet. Next job! Although I say I would give

anything to find relief, I really don't want to put my stomach, liver,

and kidneys at risk in the process!

Please enlighten me if I have interpreted any of the reports incorrectly,

as some of the language is pretty technical, and I'm not a medical person

- only teach 5th grade!

ne, 59, Lawrenceville, NJ

On Fri, 9 Apr 1999 00:04:25 EDT RAINBOWPED@... writes:

>From: RAINBOWPED@...

>

>www.cox2facts.com

>

>Warning: published by the makers of Tylenol

>

>------------------------------------------------------------------------

>Did you know that ONElist hosts some of the largest lists on the

>Internet?

>http://www.ONElist.com

>Our scaleable system is the most reliable free e-mail service on the

>Internet!

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>This forum is for support only. The information posted to this List

>is for support purposes

>and is not intended to replace the examination, diagnosis and

>treatment of a licensed

>physician and no such claims are inferred.

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Guest guest

Just went back to askjeeves and it DOES say that Celebrex has fewer GI

problems, and that renal problems are rare. (should have done this

before writing the first time!) Also looked up Aleve (Naproxen) and that

has more adverse reactions than either of 1 or 2. I'm getting

confused at this point - a little knowledge is a dangerous thing!

Anxiety may be my next " syndrome " !

ne, 59, Lawrenceville, NJ

On Fri, 9 Apr 1999 00:04:25 EDT RAINBOWPED@... writes:

>From: RAINBOWPED@...

>

>www.cox2facts.com

>

>Warning: published by the makers of Tylenol

>

>------------------------------------------------------------------------

>Did you know that ONElist hosts some of the largest lists on the

>Internet?

>http://www.ONElist.com

>Our scaleable system is the most reliable free e-mail service on the

>Internet!

>------------------------------------------------------------------------

>This forum is for support only. The information posted to this List

>is for support purposes

>and is not intended to replace the examination, diagnosis and

>treatment of a licensed

>physician and no such claims are inferred.

___________________________________________________________________

You don't need to buy Internet access to use free Internet e-mail.

Get completely free e-mail from Juno at http://www.juno.com/getjuno.html

or call Juno at (800) 654-JUNO [654-5866]

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  • 1 month later...
Guest guest

In a message dated 6/4/99 6:27:32 PM !!!First Boot!!!, nat@...

writes:

<< When the highly touted painkiller came out called Celebrex, it was supposed

to be the greatest and put all other painkiller in the dust >>

Well, actually Celebrex was highly touted as the " first agent to target only

COX-2 " and it was not proclaimed to be the " greatest " painkiller. It was

proclaimed to be a scientific breakthrough for the treatment of both

Osteoarthritis (OA) and Rheumatoid Arthritis (RA); however, not the

" greatest " painkiller (that sounds like the advertisements for Ultram).

Celebrex is touted as " powerful relief " .......relief of inflammation and pain

of OA and RA that is AS EFFECTIVE AND SIMILAR as naproxen 1,000 mg daily.

Other " claims " by Celebrex is " safely delivered " and " with flexible dosing. "

Also, it has claimed " significant improvement of the pain and inflammation of

RA vs placebo. "

I take Celebrex for my OA (knee) and it is WONDERFUL! When my knee acts-up

(pain, swelling), aside from my RLS, I simply take my Celebrex and I AM PAIN

FREE and walking around like I did in my pre-football/pre-knee injury days!

I don't take it for my RLS but it is great for my OA! IMHO

RAINBOWPED@...

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In a message dated 6/4/99 6:27:32 PM !!!First Boot!!!, nat@...

writes:

<< When the highly touted painkiller came out called Celebrex, it was supposed

to be the greatest and put all other painkiller in the dust >>

Well, actually Celebrex was highly touted as the " first agent to target only

COX-2 " and it was not proclaimed to be the " greatest " painkiller. It was

proclaimed to be a scientific breakthrough for the treatment of both

Osteoarthritis (OA) and Rheumatoid Arthritis (RA); however, not the

" greatest " painkiller (that sounds like the advertisements for Ultram).

Celebrex is touted as " powerful relief " .......relief of inflammation and pain

of OA and RA that is AS EFFECTIVE AND SIMILAR as naproxen 1,000 mg daily.

Other " claims " by Celebrex is " safely delivered " and " with flexible dosing. "

Also, it has claimed " significant improvement of the pain and inflammation of

RA vs placebo. "

I take Celebrex for my OA (knee) and it is WONDERFUL! When my knee acts-up

(pain, swelling), aside from my RLS, I simply take my Celebrex and I AM PAIN

FREE and walking around like I did in my pre-football/pre-knee injury days!

I don't take it for my RLS but it is great for my OA! IMHO

RAINBOWPED@...

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In a message dated 6/4/99 6:27:32 PM !!!First Boot!!!, nat@...

writes:

<< When the highly touted painkiller came out called Celebrex, it was supposed

to be the greatest and put all other painkiller in the dust >>

Well, actually Celebrex was highly touted as the " first agent to target only

COX-2 " and it was not proclaimed to be the " greatest " painkiller. It was

proclaimed to be a scientific breakthrough for the treatment of both

Osteoarthritis (OA) and Rheumatoid Arthritis (RA); however, not the

" greatest " painkiller (that sounds like the advertisements for Ultram).

Celebrex is touted as " powerful relief " .......relief of inflammation and pain

of OA and RA that is AS EFFECTIVE AND SIMILAR as naproxen 1,000 mg daily.

Other " claims " by Celebrex is " safely delivered " and " with flexible dosing. "

Also, it has claimed " significant improvement of the pain and inflammation of

RA vs placebo. "

I take Celebrex for my OA (knee) and it is WONDERFUL! When my knee acts-up

(pain, swelling), aside from my RLS, I simply take my Celebrex and I AM PAIN

FREE and walking around like I did in my pre-football/pre-knee injury days!

I don't take it for my RLS but it is great for my OA! IMHO

RAINBOWPED@...

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In a message dated 6/6/99 3:34:19 PM !!!First Boot!!!, KMTW4825@...

writes:

<< if you are there I have a question regarding the Celebrex.... But

I

believe you mentioned that you take it when you need it and not

everynight/day. Is that correct? If so are you then saying you take it

almost as a pain medication? How many mgs. do you take. I was only taking

50 at night but the doc said I could increase it. >>

I do not take Celebrex every day 'cause of the dyspepsia......heart burn.

I take it when my osteoarthritic knee is acting-up. Also, I make sure that I

take it with food/drink and I will sometimes chase-it with an antacid too

(e.g. Zantac, MOM, Tums or Tritec).

It is my understanding that Celebrex only comes in 100mg or 200 mg caps.

Supposedly, 100mg twice a day or 200 mg once a day for osteoarthritis and

200mg twice a day for rheumatoid arthritis. I usually take 100mg once or

twice a day depending on the severity of my knee. Rarely, I will take 200mg

twice a day if absolutely really necessary but I don't like to do that 'cause

I am worried about ulcers, you know.

I use to take Indocin-SR (75mg) and it worked great for my knee along with an

unexpected benefit that it seemed to really help my RLS! In fact, I was at

the point where I would take my Indocin routinely for my RLS instead of just

for my knee pain. If I had an absolute choice between my Permax or my

Indocin for my RLS, I would choose the Indocin! Really! However,

unfortunately, the Indocin was really tough on my stomach and I could not

continue doing that. Unfortunately, the Celebrex does not seem to have much

effect on my RLS but it is wonderful for my knee.

IMHO & YMMV

RAINBOWPED@...

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In a message dated 6/6/99 3:34:19 PM !!!First Boot!!!, KMTW4825@...

writes:

<< if you are there I have a question regarding the Celebrex.... But

I

believe you mentioned that you take it when you need it and not

everynight/day. Is that correct? If so are you then saying you take it

almost as a pain medication? How many mgs. do you take. I was only taking

50 at night but the doc said I could increase it. >>

I do not take Celebrex every day 'cause of the dyspepsia......heart burn.

I take it when my osteoarthritic knee is acting-up. Also, I make sure that I

take it with food/drink and I will sometimes chase-it with an antacid too

(e.g. Zantac, MOM, Tums or Tritec).

It is my understanding that Celebrex only comes in 100mg or 200 mg caps.

Supposedly, 100mg twice a day or 200 mg once a day for osteoarthritis and

200mg twice a day for rheumatoid arthritis. I usually take 100mg once or

twice a day depending on the severity of my knee. Rarely, I will take 200mg

twice a day if absolutely really necessary but I don't like to do that 'cause

I am worried about ulcers, you know.

I use to take Indocin-SR (75mg) and it worked great for my knee along with an

unexpected benefit that it seemed to really help my RLS! In fact, I was at

the point where I would take my Indocin routinely for my RLS instead of just

for my knee pain. If I had an absolute choice between my Permax or my

Indocin for my RLS, I would choose the Indocin! Really! However,

unfortunately, the Indocin was really tough on my stomach and I could not

continue doing that. Unfortunately, the Celebrex does not seem to have much

effect on my RLS but it is wonderful for my knee.

IMHO & YMMV

RAINBOWPED@...

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  • 2 years later...
Guest guest

the whole idea of nsaids and acne and rosacea treatment began over a

decade ago wherein kligman did a study with ibuprofen and

tetracycline combined for patients resistant to tetracycline

treatment. the study turned out well, but this idea never really

took off. instead, for quick relief of acne and inflammatory

rosacea, especially terrible forms such as acne congloblata and

rosacea fulminans, prednisolone is worked into the treatment

regimen. this is really unfortunate because of the bad metabolic and

endocrinologic problems of corticosteroids. if some sort of nsaid

regimen could be shown to be equal or better than corticosteroids,

this would be a great advance in inflammatory rosacea treatment.

we need a good trial of all the newer nsaids at various doses with

and without antibiotics to see what is the optimal remigmen, if any.

currently no one really knows for sure the true status and efficacy

of nsaids in the treatment of rosacea.

> Following the recent queries about Celebrex. It is one of the new

type of anti-inflammatories. I have been taking it for the past 4

months for arthritis. It helps with the inflammation and joint

pain. However, reading the list of side effects is very offputting!

I haven't noticed any difference with my rosacea while I've been

taking it.

>

> Gill

>

>

>

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Guest guest

the whole idea of nsaids and acne and rosacea treatment began over a

decade ago wherein kligman did a study with ibuprofen and

tetracycline combined for patients resistant to tetracycline

treatment. the study turned out well, but this idea never really

took off. instead, for quick relief of acne and inflammatory

rosacea, especially terrible forms such as acne congloblata and

rosacea fulminans, prednisolone is worked into the treatment

regimen. this is really unfortunate because of the bad metabolic and

endocrinologic problems of corticosteroids. if some sort of nsaid

regimen could be shown to be equal or better than corticosteroids,

this would be a great advance in inflammatory rosacea treatment.

we need a good trial of all the newer nsaids at various doses with

and without antibiotics to see what is the optimal remigmen, if any.

currently no one really knows for sure the true status and efficacy

of nsaids in the treatment of rosacea.

> Following the recent queries about Celebrex. It is one of the new

type of anti-inflammatories. I have been taking it for the past 4

months for arthritis. It helps with the inflammation and joint

pain. However, reading the list of side effects is very offputting!

I haven't noticed any difference with my rosacea while I've been

taking it.

>

> Gill

>

>

>

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Guest guest

the whole idea of nsaids and acne and rosacea treatment began over a

decade ago wherein kligman did a study with ibuprofen and

tetracycline combined for patients resistant to tetracycline

treatment. the study turned out well, but this idea never really

took off. instead, for quick relief of acne and inflammatory

rosacea, especially terrible forms such as acne congloblata and

rosacea fulminans, prednisolone is worked into the treatment

regimen. this is really unfortunate because of the bad metabolic and

endocrinologic problems of corticosteroids. if some sort of nsaid

regimen could be shown to be equal or better than corticosteroids,

this would be a great advance in inflammatory rosacea treatment.

we need a good trial of all the newer nsaids at various doses with

and without antibiotics to see what is the optimal remigmen, if any.

currently no one really knows for sure the true status and efficacy

of nsaids in the treatment of rosacea.

> Following the recent queries about Celebrex. It is one of the new

type of anti-inflammatories. I have been taking it for the past 4

months for arthritis. It helps with the inflammation and joint

pain. However, reading the list of side effects is very offputting!

I haven't noticed any difference with my rosacea while I've been

taking it.

>

> Gill

>

>

>

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