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Re: CMTUS

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<< CMT (in my living family) starts with my Grandmother (walker 50, wheel

chair 65), my two uncles have it & my mom, three of my four sisters have it &

I have it. So much for fifty/fifty chance of passing it on -- it hasn't

worked that way in my family for a few generations. >>

Hi Natilee,

Welcome to the group.

Regarding the 50% chance, I assume you have type 1A since you were confirmed

by the genetic test which doesn't apply to most of the other types. Type 1A

is Autosomal Dominant, which means that there is a 50% chance, in EACH

pregnancy, of the children of the affected person having CMT.

Each child has the same 50% chance no matter how many children are born. In

some families the hit rate is up to 100%. In some families it's a small hit

rate. It varies and seems to be unpredictable.

There is an incidence of 18% sporadic cases of type 1A with no family history.

I hope this helps. Any time you have questions or suggestions, always feel

free to speak up.

Regards,

Kat

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In a message dated 1/11/00 10:06:05 AM Pacific Standard Time,

natilee@... writes:

<< Just found your site -- what a nice surprise. I was looking for a support

group and decided to check and see if there was one for CMT -- what a nice

surprise. >>

Nice to meet you Natilee, Sounds like your CMT is mild. What problems if any

have you run into? They think my Dad may have had a very mild case. he was

not every really bothered by it if thats what he had.

jenny

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In a message dated 1/11/00 1:44:38 PM Pacific Standard Time,

KathleenLS@... writes:

<< Regarding the 50% chance, I assume you have type 1A since you were

confirmed

by the genetic test which doesn't apply to most of the other types. Type 1A

is Autosomal Dominant, which means that there is a 50% chance, in EACH

pregnancy, of the children of the affected person having CMT.

Each child has the same 50% chance no matter how many children are born. In

some families the hit rate is up to 100%. In some families it's a small hit

rate. It varies and seems to be unpredictable. >>

yeah but it seems like it can all even out if you play the odds,

jenny

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