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RLS--Dr. Levin--Two questions

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Dick:

I'd like to follow up on a couple of responses you recently made, if I

might.

You mentioned to Tina that, " Drug holidays for Mirapex are not

necessary. " Am I correct in inferring from that reply that rebound and

augmentation are not a problem with Mirapex? Or did you just mean that

holidays aren't helpful in preventing them insofar as Mirapex is

concerned?

In a different message, you said to that, " Vistaril (also marketed

as

Atarax) is pretty safe and typically does not bother RLS patients even

though it has antihistaminic actions. " Should I infer from this that

most antihistamines frequently exacerbate RLS symptoms? I knew that

benedryl and its brethren had this reputation, but I wasn't aware this

was true for most, if not all, antihistamines. Assuming this is so, is

there an antihistamine (Allegra? Claritin?) that's preferred for RLS

sufferers?

Thanks in advance for your thoughts.

Hal

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