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Re: RLS/pyridoxine (Vitamin B6)

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June

Good luck with the new Support Group. If

a person is taking l-dopa for

Parkinson's Disease, pyridoxine can

increase the rate of breakdown of the

l-dopa in the bloodstream leaving less

to cross into the brain. The carbidopa

in Sinemet blocks this action of

pyridoxine, so Sinemet and pyridoxine

can be taken together. Permax

(pergolide) has a completely different

chemical structure than l-dopa. A search

of the literature reveals no interaction

between pyridoxine and pergolide. I

think that there has been a breakdown in

communication somewhere along the line.

When you get the Support Group up and

running, you will find that

misinformation is very common and

difficult to deal with. If I am missing

something, I would appreciate the

education.

Dr. Levin

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