Need help Antinausea drugs!

[Guest guest]

Hi gang,

Elaine reminds me having had the lymph node procedure (I am so happy it

turned out negative Elaine! Our prayers and thoughts are with you, make it

30,275 with us and the monks!).

I wondered if when an antinausea drug was indicated, if an opioid such as

Percocet given at the same time might counter the exacerbation of the RLS

symptoms? Has anyone had an experience with taking both and living through it

or do the RLS symptoms get so much worse, nothing helps? The only one that

might not exacerbate RLS symptoms is a drug given chemotherapy patients,

Kytril. I talked to my pharmacy and they do not stock it but could have it by

the next day. For two, it might be $100; ten $450. Take 2 a day. See Dr.

Buchfurfer's post on it below for more info.

This is a real problem as some times such as after surgery, antinausea drugs

are indicated. However, my next thought is that if you have had surgery, most

would be given opioids also and still report going nuts with RLS.

Appreciate feedback on this! Below is my Antinausea Drug file. I only heard

from 4 of approximately 275 it is fine to post my files even though some of

your past posts will be available on the Internet.

I have made every effort to erase identifying data, names, etc. but gee, some

of the files are so large, I might have missed something and don't want to

get in the dog house with anyone. Remember, these files will be available to

everyone with access to the Internet via Jodi's Web Site.

I am checking with Dr. Buchfurher and Dr. Levin it is okay to leave their

names on the posts although erase there E-mail addresses. I think knowing it

has come from a doctor is significant.

Erstwhile RLS Librarian

AKA as the Ferritin Lady,

Barbara

Subj: Re: Nausea Drugs; Help Dr. Buchfuher!

Date: 3/17/99 3:56:07 AM Eastern Standard Time

There are new classes of antiemetics (antinausea drugs) that are quite

chemically different from the old ones that are related to the antihistamines

(which tend to bother RLS). Kytril is one example. It works very well and is

used in chemotherapy patients to stop nausea. Unfortunately, it needs a

prescription and is quite expensive.

I can't guarantee that it won't cause the RLS to worsen (with new drugs one

can never tell), but it is quite chemically different so the chances are good

that it won't cause trouble. MJB

Hi, Both of my children have RLS, as do I. They are 14 and 15. I took the

15 yr old to the emergency room two weeks ago tonight with stomach pains to a

hospital near our home. The CT scan said it was pancreatitis, not

appendicitis, as the surgeon thought. While we were still in the ER, son

felt nauseous and they gave him a shot of phenergran. Poor baby's legs

started shooting what seemed like to the ceiling. When it finally wore off,

needless to say, I told the ER not to give him any more (We were there seven

hours before they admitted him.) I asked the ER doc for pain meds, not

phenergran, but he never got it.

After they admitted him, I asked the admitting doc to give him something for

pain. Well, it was Demerol AND Phenergran. Amid my protests, the nurse

insisted it was only a small amount of phenergran to keep the demerol from

upsetting his stomach. So I let her give it to him. He went to sleep and

his legs didn't move. So, I guess I can deduct that the narcotic in the

demerol overrode the small amount of phenergran that was in the injection.

After the doctors couldn't agree on what to do--the GI doc wanted to do

exploratory surgery and the surgeon said he didn't feel right about it--we

called in another surgeon. He said that 15 yr.- olds don't just " get "

pancreatitis and to send him to Texas Children's in Houston. So we got in an

ambulance and went to Houston (45 miles south). Although all of the

hospitals in the Medical Center were on Drive-by status that night, they took

my son and put him in a room right away, even though the waiting rooms and

halls were full of patients. Son immediately said he was nauseous, and I

went through the whole story again. I said if you give him phenergran, you

have to give him the demerol with it. The demerol and phenergran worked

again--no RLS.

Everyone at both hospitals was very nice and listened. Although some of the

staff didn't know about RLS, others did, everyone was very nice and honored

my requests, which were in the best interests of my son. After spending 21

hours in the Texas Children's ER--there weren't any rooms-- we finally go to

a room and the doctor said his pancreatitis was caused by a virus....My next

step is to find a doctor that treats pediatric RLS. (My neuro here won't see

them until they are 20.)

BTW. Phenergran doesn't effect me except relieve my nausea--thank goodness. L

Hi folks, Just had a nasty nasty bout of the flu and in desperation took some

phenegran. Biiiggggg mistake...Hugging the porcelain god all night on the one

hand...and the arms and legs doing the jitterbug all night on the

other....hmmmmm...... what a choice. Does anyone else get the same reaction

from that medication? And if so.... care to picket with me? kidding!! X

D, Thanks for the ginger tip, i take two herbal ginger tablets when i take

the permax (around 6pm) but maybe i should take more or add the herbal tea.

i have ancestors in Ireland but nobody alive. i am going with my two sisters

and mom, of course the joke is who will stay in my room. when i was little

my sister had to share a bed with me, this only lasted two nights because of

my kicking. but i will not let my legs take the fun out of Ireland!!!!

thanks for the tip, i will also try eating an apple. you guys are so

helpful, how did i survive before the emails!! M

Hi , Glad the Permax is working. Sorry it is making you nauseous. There

are several things you can try. Taking Permax with food sometimes helps.

Cutting back on the dosage to find the smallest dose that still gives relief

might help. There is a drug called " domeperidone " that blocks the effect of

dopamine on the stomach without blocking its action on the brain. This drug

has been used successfully with Permax to reduce the nausea and other side

effects. It is not available in the US but your physician can get it from the

Canadian manufacturer and legally have it imported into the US. Hope some of

this helps. Dr. Levin

[Guest guest]

Barbara:

Before, during and after my sinus surgery in March, I was being given injections

of Demerol,

first, for the sinus migraines and then for the pain after the surgery. Well,

the Demerol made

me nauseous, so they started mixing the injection with Phenergan. I've never had

good luck with

Phenergan (instant RLS attack when taken by pill form), but I never had one bit

of trouble with

the RLS the entire 6 days that I was in the hospital. When I was released, I was

given a

prescription for and antibiotic (which made me nauseous), Phenergan to take

about 20 minutes

before taking it, and Percocet, and, I'm glad to say that I made it through it

just fine. And,

with no RLS symptoms at all. As a matter of fact, it's been a little over 8

weeks since my

surgery and I still haven't had any problems with the RLS???? Maybe that's why

I've been so

quiet here lately, I'm not on any medications, except Flonase Nasal Spray (twice

a day) and an

occasional Darvocet N-100 when I get one of my famous sinus headaches, which is

a couple of

times a week. Even the surgery didn't completely alleviate those, although they

are not nearly

as severe as they were before the surgery. I think that I must be in some sort

of " remission "

from the RLS. I have had two instances during this period of time that my legs

have acted up

early in the morning, usually right before the alarm goes off. Once I get up,

the symptoms go

away as I'm moving around and they don't return. I don't know what the heck is

going on here,

but I'm definitely not complaining. I've even been riding my bike again and, of

course, now that

the weather has warmed up, the jetski is out of the garage, but even the

exercise has

exasperated the RLS. I'm just praying that it stays this way, as I feel so much

better since

getting off of all of those meds that I was on, plus since having the surgery,

I've got the

energy level of a 20-year old again. Probably, a little too much of it, as I'm

only averaging

4-5 hours of sleep a night and I feel like I've slept 8-10. I just pray to God

that this could

happen to everybody (not the sinus surgery, LOL), but the " remission " of the

symptoms.

Restful Nights,

Jodi

SurSiliImp@... wrote:

> From: SurSiliImp@...

>

> Hi gang,

>

> Elaine reminds me having had the lymph node procedure (I am so happy it

> turned out negative Elaine! Our prayers and thoughts are with you, make it

> 30,275 with us and the monks!).

>

> I wondered if when an antinausea drug was indicated, if an opioid such as

> Percocet given at the same time might counter the exacerbation of the RLS

> symptoms? Has anyone had an experience with taking both and living through it

> or do the RLS symptoms get so much worse, nothing helps? The only one that

> might not exacerbate RLS symptoms is a drug given chemotherapy patients,

> Kytril. I talked to my pharmacy and they do not stock it but could have it by

> the next day. For two, it might be $100; ten $450. Take 2 a day. See Dr.

> Buchfurfer's post on it below for more info.

>

> This is a real problem as some times such as after surgery, antinausea drugs

> are indicated. However, my next thought is that if you have had surgery, most

> would be given opioids also and still report going nuts with RLS.

>