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Hi group,

I just made an interesting discovery that might prove useful to others

in the group. I have been taking Mirapex for four months. It has

significantly improved the quality of my life. But, like you, I worry that

the " cure " will be short lived. Recently the Mirapex has become less

effective, with some augmentation of symptoms during the day. I feared that

I would have to increase my dosage and that I would soon have to try other

medications (nothing else has been successful so far.) Then I discovered on

one of the rls sites, a list of things for rls patients to avoid. On that

list were calcium channel-blocking agents. They are dopomine antagonists.

I have high-blood pressure. My original medication caused side effects. I

switched to my current med, you got it, a calcium channel-blocker, last

month. Needless to say, I will see my gp next week and change meds. I

hope that that will improve things.

This was a reminder to me that we are all responsible for getting the

information that we need. My gp and neurologist are working together, but

neither of them knew about this possible drug interaction, nor for that

matter did the pharmacist who fills both prescriptions. I really don't fault

them. This disease is very complicated. Only we have the time, motivation

and fortunately now, the resources to pursue all leads.

I will let you know how things work out. Til then, take a short nap for

me.

Kathy, 56 PA

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