Re: Diane's ? about cheese when previously GFCF

November 17, 2005

Diane,

My daughter was GFCF for years when we went SCD. I'm also SCD. I eat the

yogurt and cheese, but so far have mostly avoided giving it to her. However, I

have made a couple of things with the dairy, such as SCD pumpkin pie, and we use

butter on her food or as a recipe ingredient occasionally. I just look for a

reaction when it slips into her diet. (In the pre-CF days many years ago, a

reaction would be her whining in bed all night rather than sleeping--we haven't

seen any kind of reaction on SCD, certainly not that.) Everyone on this list

advises to go slowly introducing legal dairy to ASD kids who were CF, and this

is my way of going slowly. My daughter won't eat yogurt, but I will sneak it in

as ingredient and watch for reactions.

Nannette, IBS, SCD 2 months

daughter, , autism, 13 yo, SCD 2 months

-Original message-

I'm wondering if other parents who

were previously doing GFCF with their children are now doing straight SCD

(and not eliminating casein). If any other parents out there care to

comment on this that would be great. If my son could have cheese again he

would be one happy camper.

Diane

November 18, 2005

>

> Diane,

> My daughter was GFCF for years when we went SCD. I'm also SCD. I eat the

yogurt and

cheese, but so far have mostly avoided giving it to her.

Personally I find it sad that GF has made such a bogeyman out of dairy when so

many do

find they can tolerate it on SCD. I am not inferring that there is no such thing

as casein

allergy, sensitivity or whatever you want to call it. It is just that if you

took a poll of our

nearly 2050 members you might be surprised at how many who wouldn't touch dairy

can

now use yogurt and properly aged cheese

Carol F.

Toronto, Celiac, SCD 5 years

November 18, 2005

The reason that our kids can eat yogurt and cheese after

implementing SCD is that the healed gut can tolerate the dairy

better. The dairy intolerance of most ASD children is caused by

endotoxins emitted by gut bacteria. SCD is good at eliminating those

bacteria.

Below my email,I have put copies of the research article and

Elaine's comments concerning it.

Mimi

Jyonouchi's Paper

Neuropsychobiology. 2002;46(2):76-84.

Elaine Gottschall's Comments on Jyonouchi's Paper

The abstract of Jyonouchi's paper says Children with autism

spectrum disorder (ASD) frequently reveal various gastrointestinal

(GI) symptoms that may resolve with an elimination diet along with

apparent improvement of some of the behavorial symptoms. Evidence

suggests that ASD may be accompanied by aberrant (inflammatory)

innate immune responses. THIS MAY PREDISPOSE ASD CHILDREN TO

SENSITIVIES TO COMMON DIETARY PROTEINS LEADING TO GI INFLAMMATION

AND AGGRAVATION OF SOME BEHAVIORAL SYMPTOMS.

The authors demonstrate conclusively that there is an abnormal

immune response to cow's milk protein and wheat protein (gliadin)

and soy in ASD. What is interesting is that the diet model is NOT

THE SAME AS THE OPIOID MODEL BUT IS BASED ON A VARIABLE IMMUNE

RESPONSE IN WHICH NOT EVERY CHILD WILL SHOW SENSITIVITY TO EVERY

FOOD.

But the punch line is: The authors suggest that the root cause of

the food protein sensitivity may be an underlying sensitivity to

endotoxin or lipopolysaccharides (LPS) which comes from the surfaces

of gram negative bacteria in the gut.

This summarized means that this response to the bacterial endotoxin

(LPS) PREDISPOSE THESE CHILDREN TO SENSITIZATION TO DIETARY

PROTEINS. This is consistent with a model of abnormal gut flora

development that promotes immune response to gut bacteria. This

means that ASD kids may develop a kind of autoimmunie response to

their own gut flora.

Neuropsychobiology. 2002;46(2):76-84

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1\

2378124&dopt=Abstract

Innate immunity associated with inflammatory responses and cytokine

production against common dietary proteins in patients with autism

spectrum disorder.

Jyonouchi H, Sun S, Itokazu N.

Department of Pediatrics, University of Minnesota, Minneapolis,

Minn, USA.

OBJECTIVES: Children with autism spectrum disorder (ASD) frequently

reveal various gastrointestinal (GI) symptoms that may resolve with

an elimination diet along with apparent improvement of some of the

behavioral symptoms. Evidence suggests that ASD may be accompanied

by aberrant (inflammatory) innate immune responses. This may

predispose ASD children to sensitization to common dietary proteins

(DP), leading to GI inflammation and aggravation of some behavioral

symptoms. METHODS: We measured IFN-gamma, IL-5, and TNF-alpha

production against representative DPs [gliadin, cow's milk protein

(CMP), and soy] by peripheral blood mononuclear cells (PBMCs) from

ASD and control children [those with DP intolerance (DPI), ASD

siblings, and healthy unrelated children]. We evaluated the results

in association with proinflammatory and counter-regulatory cytokine

production with endotoxin (LPS), a microbial product of intestinal

flora and a surrogate stimulant for innate immune responses.

RESULTS: ASD PBMCs produced elevated IFN-gamma and TNF-alpha, but

not IL-5 with common DPs at high frequency as observed in DPI PBMCs.

ASD PBMCs revealed increased proinflammatory cytokine responses

with LPS at high frequency with positive correlation between

proinflammatory cytokine production with LPS and IFN-gamma and

TNF-alpha production against DPs. Such correlation was less evident

in DPI PBMCs. CONCLUSION: Immune reactivity to DPs may be associated

with apparent DPI and GI inflammation in ASD children that may be

partly associated with aberrant innate immune response against

AG, Basel

PMID: 12378124 [PubMed - indexed for MEDLINE]

November 18, 2005

Got behind on my emails (on too many lists!).

Thanks so much to all who responded about cheese/casein. This is helpful

and encouraging information.