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Movement Disorder Researchers meeting in Austria, Feb 20-21, 2003

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Note another new name for these related disorders " proteinopathies " .

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http://www.movementdisorders.org/symposia.html

Atypical Parkinsonian Disorders: From Protein Dysfunction to Therapeutic

Intervention

February 20-21, 2003 Department of Neurology,

University Hospital

Innsbruck, Austria

Program Description

Movement disorder experts are increasingly faced with atypical parkinsonian

disorders (APDs) such as multiple system atrophy (MSA), progressive

supranuculear palsy (PSP), or corticobasal degeneration (CBD). Until

recently, the molecular pathology of APDs remained elusive preventing the

development of effective therapeutic interventions. Previous meetings on CBD

and MSA addressed clinical, diagnostic and neuropathological aspects of

these disorders. During the last five years fundamental insights into the

synuclein and/or tau pathology of APDs have led to a new understanding of

these disorders as proteinopathies.

European and US MSA study groups will be launched in January 2001 aiming at

rating scale development, natural history studies, ecogenetic research and

ultimately at neuroprotective intervention trials. Recently, the NNIPPS

trial consortium in Europe launched a double blind multicentre trial of

rilzole in PSP and MSA. The proposed symposium will review the current

evidence for abnormal protein handling as primary pathogenic event in APDs;

it will also review experimental models and therapeutic strategies in these

disorders. The ongoing research activities of the European and US MSA Study

Groups and the NNIPPS consortium will be presented.

Meeting Organizer: Gregor Wenning, MD, PhD

Anichstrasse 35, A-6020

Innsbruck, AUSTRIA

TEL: 43

FAX: 43

Email: gregor.wenning@...

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