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Bill behave! :)

Re: MSA RESEARCH STUDY

> Pam,

>

> I agree about the more positive note :o) But isn't Dr. Shults a

neurologist

> :o) I agree also that getting as many people involved with this study as

> possible, could help find an eventual cure for MSA.

>

> Hugs back, Bill Werre

>

> --------------------------------------

>

> Pam Bower wrote:

>

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us out of

the

> > blue last week? I know I'm not the only one who is excited about it.

I've

> > heard lots of you have filled it out and sent it in. Even if you put a

NO

> > beside the question about whether you are willing or able to travel I

think

> > it's REALLY, REALLY important that Dr. Shults knows who you are and

where

> > you are located. We don't know for sure that those 7 centers will be

the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> > Hugs,

> > Pam

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Guest guest

Bill behave! :)

Re: MSA RESEARCH STUDY

> Pam,

>

> I agree about the more positive note :o) But isn't Dr. Shults a

neurologist

> :o) I agree also that getting as many people involved with this study as

> possible, could help find an eventual cure for MSA.

>

> Hugs back, Bill Werre

>

> --------------------------------------

>

> Pam Bower wrote:

>

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us out of

the

> > blue last week? I know I'm not the only one who is excited about it.

I've

> > heard lots of you have filled it out and sent it in. Even if you put a

NO

> > beside the question about whether you are willing or able to travel I

think

> > it's REALLY, REALLY important that Dr. Shults knows who you are and

where

> > you are located. We don't know for sure that those 7 centers will be

the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> > Hugs,

> > Pam

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Guest guest

Bill behave! :)

Re: MSA RESEARCH STUDY

> Pam,

>

> I agree about the more positive note :o) But isn't Dr. Shults a

neurologist

> :o) I agree also that getting as many people involved with this study as

> possible, could help find an eventual cure for MSA.

>

> Hugs back, Bill Werre

>

> --------------------------------------

>

> Pam Bower wrote:

>

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us out of

the

> > blue last week? I know I'm not the only one who is excited about it.

I've

> > heard lots of you have filled it out and sent it in. Even if you put a

NO

> > beside the question about whether you are willing or able to travel I

think

> > it's REALLY, REALLY important that Dr. Shults knows who you are and

where

> > you are located. We don't know for sure that those 7 centers will be

the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> > Hugs,

> > Pam

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Guest guest

Pam,

I agree about the more positive note :o) But isn't Dr. Shults a neurologist

:o) I agree also that getting as many people involved with this study as

possible, could help find an eventual cure for MSA.

Hugs back, Bill Werre

--------------------------------------

Pam Bower wrote:

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it. I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

> Hugs,

> Pam

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Guest guest

Pam,

I agree about the more positive note :o) But isn't Dr. Shults a neurologist

:o) I agree also that getting as many people involved with this study as

possible, could help find an eventual cure for MSA.

Hugs back, Bill Werre

--------------------------------------

Pam Bower wrote:

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it. I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

> Hugs,

> Pam

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Guest guest

Pam,

I agree about the more positive note :o) But isn't Dr. Shults a neurologist

:o) I agree also that getting as many people involved with this study as

possible, could help find an eventual cure for MSA.

Hugs back, Bill Werre

--------------------------------------

Pam Bower wrote:

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it. I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

> Hugs,

> Pam

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Guest guest

I missed that note somewhere along the way. Was it just for current

patients?

--

" You have to wonder about humans, they think God is dead

and Elvis is still alive! " Anon

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Guest guest

Barb,

:o) Yes, you and I are not needed as they want to try to find patients who

they can follow for something like five years (see below). This is extremely

good for people who are still walking or recently moving to wheelchairs. To

my knowledge previous studies have looked at all movement disorders or all

autonomic failure rather than specifically targeting MSA.

Take care, Bill

-----------------

Barb wrote:

> I missed that note somewhere along the way. Was it just for current

> patients?

>

> --

> " You have to wonder about humans, they think God is dead

> and Elvis is still alive! " Anon

*** MSA Research Study Announcement ***

May 20, 2002

The North American Multiple System Atrophy (MSA) Study Group is

working to develop a comprehensive research effort into MSA, and the

clinical part of the research will be carried out at seven medical

centers in the United States. These centers include the University

of California, San Diego (La Jolla, California), Parkinson's

Institute (Sunnyvale, California), Mayo Clinic (Rochester,

Minnesota), University of Michigan (Ann Arbor, Michigan), s

Hopkins University (Baltimore, land), University of Pennsylvania

(Philadelphia, Pennsylvania), and University of Rochester (Rochester,

New York).

A major part of this effort will be to evaluate 150 MSA patients with

two examinations each year for up to five years at one of the seven

clinical centers. Patients with MSA will also be asked to identify

two non-blood relatives (spouses or in-laws) who would be willing to

be evaluated once. MSA patients will also be asked to participate in

a telephone interview, which will try to identify factors, such as

diet or exposure to certain chemicals, that might cause MSA.

Our proposal to the National Institutes of Health for support has not

yet received funding. Reviewers of our proposed research questioned

whether 150 MSA subjects would be willing and able to be evaluated

two times each year. To respond to this concern our group would like

to identify MSA patients who would be willing to come to one of the

above centers two times each year for an evaluation. We realize

after a few years travel may become very difficult for some MSA

patients, and then we will try to obtain the needed information

through a telephone call. These evaluations will not replace the

ongoing care that the MSA patient is receiving from her/his

physician.

If you are interested in possibly participating in this study once it

has received funding, please complete the questionnaire, which is

pasted below and also enclosed as an attachment, and mail (please do

not use email) to

Cliff Shults M.D.

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

The information that you provide will remain confidential. Dr. Shults

will try to call you within two weeks of receipt of the questionnaire

to answer questions regarding the planned study and clarify any

questions that he has regarding the information that you provided.

Sincerely,

Cliff Shults, M.D.

Professor of Neurosciences

University of California, San Diego

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

----------------------------

Questions for MSA patients interested in the study " Pathogenesis and

Diagnosis of Multiple System Atrophy " - #010906

1. Name _____________________________________________

2. Address____________________________________________

___________________________________________________

3. Telephone number____________________________________

4. Date of birth_________________________________________

5. Gender_____________________________________________

6. Have you been diagnosed by a doctor to have multiple system

atrophy (MSA)?

YES_____ NO_____ If so, what year was the diagnosis made?

_________

7. Was the doctor a neurologist?

YES_____ NO_____

8. Would you be willing and able come to one of the participating

medical centers to be seen by an expert in multiple system atrophy

two times each year for up to five years? Reasonable travel expenses

would be covered. There would be no cost for the evaluation.

YES_____ NO_____

9. If so, at which site

San Diego, CA_____

Sunnyvale, CA_____

Rochester, MN_____

Ann Arbor, MI_____

Baltimore, MD_____

Philadelphia, PA_____

Rochester, NY_____

10. Do you think that your spouse and/or some of your in-laws would be

willing to come to come to one of these centers once for an

evaluation?

YES_____ NO_____

11. Do you think that you, your spouse and some of your in-laws would

be willing to participate in a telephone survey investigating

possible risk factors for MSA, by asking about work, hobbies, health,

life style and family medical history?

YES_____ NO_____

12. Would you be willing to travel by airplane to a medical center

for a detailed evaluation of your autonomic system, which is the part

of the nervous system that controls blood pressure, urinary function

and bowel function?

YES_____ NO_____

13. Would you be willing to give a blood sample to study your DNA for

a genetic cause of MSA?

YES_____ NO_____

14. Do you have slowness of movement? YES_____ NO_____

15. Do you have stiffness in your muscles? YES_____ NO_____

16. Do you have extra movements such as shaking, tremor or jerks?

YES_____ NO_____

17. Do you have faintness or do you pass out? YES_____ NO_____

18. Do you have problems with control of urination (your bladder ) ?

YES_____ NO_____

19. Do you have problems with coordination of your arms?

YES_____ NO_____

20. Would you be willing to have your doctor send your medical

records to Dr. Shults for review? YES_____ NO_____

21. If you are willing to allow Dr Shults to review your medical

record for research purposes, he will mail to you a " Release of

Medical Records " form, which will allow your doctor to send your

medical records related to MSA to Dr. Shults. Please indicate

whether you would be willing allow your physician to send your

medical records related to MSA to Dr. Shults.

YES_____ NO_____

22. Please list any other medical problems you have:

23. Please list your medications.

______________________________________________________________________

__

----------------------------------------------------------------------

----------

Cliff Shults, MD

Professor of Neurosciences, UCSD

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

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Guest guest

Barb,

:o) Yes, you and I are not needed as they want to try to find patients who

they can follow for something like five years (see below). This is extremely

good for people who are still walking or recently moving to wheelchairs. To

my knowledge previous studies have looked at all movement disorders or all

autonomic failure rather than specifically targeting MSA.

Take care, Bill

-----------------

Barb wrote:

> I missed that note somewhere along the way. Was it just for current

> patients?

>

> --

> " You have to wonder about humans, they think God is dead

> and Elvis is still alive! " Anon

*** MSA Research Study Announcement ***

May 20, 2002

The North American Multiple System Atrophy (MSA) Study Group is

working to develop a comprehensive research effort into MSA, and the

clinical part of the research will be carried out at seven medical

centers in the United States. These centers include the University

of California, San Diego (La Jolla, California), Parkinson's

Institute (Sunnyvale, California), Mayo Clinic (Rochester,

Minnesota), University of Michigan (Ann Arbor, Michigan), s

Hopkins University (Baltimore, land), University of Pennsylvania

(Philadelphia, Pennsylvania), and University of Rochester (Rochester,

New York).

A major part of this effort will be to evaluate 150 MSA patients with

two examinations each year for up to five years at one of the seven

clinical centers. Patients with MSA will also be asked to identify

two non-blood relatives (spouses or in-laws) who would be willing to

be evaluated once. MSA patients will also be asked to participate in

a telephone interview, which will try to identify factors, such as

diet or exposure to certain chemicals, that might cause MSA.

Our proposal to the National Institutes of Health for support has not

yet received funding. Reviewers of our proposed research questioned

whether 150 MSA subjects would be willing and able to be evaluated

two times each year. To respond to this concern our group would like

to identify MSA patients who would be willing to come to one of the

above centers two times each year for an evaluation. We realize

after a few years travel may become very difficult for some MSA

patients, and then we will try to obtain the needed information

through a telephone call. These evaluations will not replace the

ongoing care that the MSA patient is receiving from her/his

physician.

If you are interested in possibly participating in this study once it

has received funding, please complete the questionnaire, which is

pasted below and also enclosed as an attachment, and mail (please do

not use email) to

Cliff Shults M.D.

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

The information that you provide will remain confidential. Dr. Shults

will try to call you within two weeks of receipt of the questionnaire

to answer questions regarding the planned study and clarify any

questions that he has regarding the information that you provided.

Sincerely,

Cliff Shults, M.D.

Professor of Neurosciences

University of California, San Diego

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

----------------------------

Questions for MSA patients interested in the study " Pathogenesis and

Diagnosis of Multiple System Atrophy " - #010906

1. Name _____________________________________________

2. Address____________________________________________

___________________________________________________

3. Telephone number____________________________________

4. Date of birth_________________________________________

5. Gender_____________________________________________

6. Have you been diagnosed by a doctor to have multiple system

atrophy (MSA)?

YES_____ NO_____ If so, what year was the diagnosis made?

_________

7. Was the doctor a neurologist?

YES_____ NO_____

8. Would you be willing and able come to one of the participating

medical centers to be seen by an expert in multiple system atrophy

two times each year for up to five years? Reasonable travel expenses

would be covered. There would be no cost for the evaluation.

YES_____ NO_____

9. If so, at which site

San Diego, CA_____

Sunnyvale, CA_____

Rochester, MN_____

Ann Arbor, MI_____

Baltimore, MD_____

Philadelphia, PA_____

Rochester, NY_____

10. Do you think that your spouse and/or some of your in-laws would be

willing to come to come to one of these centers once for an

evaluation?

YES_____ NO_____

11. Do you think that you, your spouse and some of your in-laws would

be willing to participate in a telephone survey investigating

possible risk factors for MSA, by asking about work, hobbies, health,

life style and family medical history?

YES_____ NO_____

12. Would you be willing to travel by airplane to a medical center

for a detailed evaluation of your autonomic system, which is the part

of the nervous system that controls blood pressure, urinary function

and bowel function?

YES_____ NO_____

13. Would you be willing to give a blood sample to study your DNA for

a genetic cause of MSA?

YES_____ NO_____

14. Do you have slowness of movement? YES_____ NO_____

15. Do you have stiffness in your muscles? YES_____ NO_____

16. Do you have extra movements such as shaking, tremor or jerks?

YES_____ NO_____

17. Do you have faintness or do you pass out? YES_____ NO_____

18. Do you have problems with control of urination (your bladder ) ?

YES_____ NO_____

19. Do you have problems with coordination of your arms?

YES_____ NO_____

20. Would you be willing to have your doctor send your medical

records to Dr. Shults for review? YES_____ NO_____

21. If you are willing to allow Dr Shults to review your medical

record for research purposes, he will mail to you a " Release of

Medical Records " form, which will allow your doctor to send your

medical records related to MSA to Dr. Shults. Please indicate

whether you would be willing allow your physician to send your

medical records related to MSA to Dr. Shults.

YES_____ NO_____

22. Please list any other medical problems you have:

23. Please list your medications.

______________________________________________________________________

__

----------------------------------------------------------------------

----------

Cliff Shults, MD

Professor of Neurosciences, UCSD

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

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Guest guest

Barb,

:o) Yes, you and I are not needed as they want to try to find patients who

they can follow for something like five years (see below). This is extremely

good for people who are still walking or recently moving to wheelchairs. To

my knowledge previous studies have looked at all movement disorders or all

autonomic failure rather than specifically targeting MSA.

Take care, Bill

-----------------

Barb wrote:

> I missed that note somewhere along the way. Was it just for current

> patients?

>

> --

> " You have to wonder about humans, they think God is dead

> and Elvis is still alive! " Anon

*** MSA Research Study Announcement ***

May 20, 2002

The North American Multiple System Atrophy (MSA) Study Group is

working to develop a comprehensive research effort into MSA, and the

clinical part of the research will be carried out at seven medical

centers in the United States. These centers include the University

of California, San Diego (La Jolla, California), Parkinson's

Institute (Sunnyvale, California), Mayo Clinic (Rochester,

Minnesota), University of Michigan (Ann Arbor, Michigan), s

Hopkins University (Baltimore, land), University of Pennsylvania

(Philadelphia, Pennsylvania), and University of Rochester (Rochester,

New York).

A major part of this effort will be to evaluate 150 MSA patients with

two examinations each year for up to five years at one of the seven

clinical centers. Patients with MSA will also be asked to identify

two non-blood relatives (spouses or in-laws) who would be willing to

be evaluated once. MSA patients will also be asked to participate in

a telephone interview, which will try to identify factors, such as

diet or exposure to certain chemicals, that might cause MSA.

Our proposal to the National Institutes of Health for support has not

yet received funding. Reviewers of our proposed research questioned

whether 150 MSA subjects would be willing and able to be evaluated

two times each year. To respond to this concern our group would like

to identify MSA patients who would be willing to come to one of the

above centers two times each year for an evaluation. We realize

after a few years travel may become very difficult for some MSA

patients, and then we will try to obtain the needed information

through a telephone call. These evaluations will not replace the

ongoing care that the MSA patient is receiving from her/his

physician.

If you are interested in possibly participating in this study once it

has received funding, please complete the questionnaire, which is

pasted below and also enclosed as an attachment, and mail (please do

not use email) to

Cliff Shults M.D.

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

The information that you provide will remain confidential. Dr. Shults

will try to call you within two weeks of receipt of the questionnaire

to answer questions regarding the planned study and clarify any

questions that he has regarding the information that you provided.

Sincerely,

Cliff Shults, M.D.

Professor of Neurosciences

University of California, San Diego

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

----------------------------

Questions for MSA patients interested in the study " Pathogenesis and

Diagnosis of Multiple System Atrophy " - #010906

1. Name _____________________________________________

2. Address____________________________________________

___________________________________________________

3. Telephone number____________________________________

4. Date of birth_________________________________________

5. Gender_____________________________________________

6. Have you been diagnosed by a doctor to have multiple system

atrophy (MSA)?

YES_____ NO_____ If so, what year was the diagnosis made?

_________

7. Was the doctor a neurologist?

YES_____ NO_____

8. Would you be willing and able come to one of the participating

medical centers to be seen by an expert in multiple system atrophy

two times each year for up to five years? Reasonable travel expenses

would be covered. There would be no cost for the evaluation.

YES_____ NO_____

9. If so, at which site

San Diego, CA_____

Sunnyvale, CA_____

Rochester, MN_____

Ann Arbor, MI_____

Baltimore, MD_____

Philadelphia, PA_____

Rochester, NY_____

10. Do you think that your spouse and/or some of your in-laws would be

willing to come to come to one of these centers once for an

evaluation?

YES_____ NO_____

11. Do you think that you, your spouse and some of your in-laws would

be willing to participate in a telephone survey investigating

possible risk factors for MSA, by asking about work, hobbies, health,

life style and family medical history?

YES_____ NO_____

12. Would you be willing to travel by airplane to a medical center

for a detailed evaluation of your autonomic system, which is the part

of the nervous system that controls blood pressure, urinary function

and bowel function?

YES_____ NO_____

13. Would you be willing to give a blood sample to study your DNA for

a genetic cause of MSA?

YES_____ NO_____

14. Do you have slowness of movement? YES_____ NO_____

15. Do you have stiffness in your muscles? YES_____ NO_____

16. Do you have extra movements such as shaking, tremor or jerks?

YES_____ NO_____

17. Do you have faintness or do you pass out? YES_____ NO_____

18. Do you have problems with control of urination (your bladder ) ?

YES_____ NO_____

19. Do you have problems with coordination of your arms?

YES_____ NO_____

20. Would you be willing to have your doctor send your medical

records to Dr. Shults for review? YES_____ NO_____

21. If you are willing to allow Dr Shults to review your medical

record for research purposes, he will mail to you a " Release of

Medical Records " form, which will allow your doctor to send your

medical records related to MSA to Dr. Shults. Please indicate

whether you would be willing allow your physician to send your

medical records related to MSA to Dr. Shults.

YES_____ NO_____

22. Please list any other medical problems you have:

23. Please list your medications.

______________________________________________________________________

__

----------------------------------------------------------------------

----------

Cliff Shults, MD

Professor of Neurosciences, UCSD

Department of Neurosciences 0662

Univ. of California San Diego - School of Medicine

9500 Gilman Drive

La Jolla, CA 92093-0662

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Guest guest

Great ! I actually just spoke with Dr. Shults on the phone.

He told me a bit of the history of his group. He first proposed forming the

North American MSA Study Group a couple years ago at one of the Neurology

Society meetings. He actually got the idea from a patient with MSA who was

wondering why no researchers were interested in it.

I told him we were thrilled that he'd got the group of researchers

collaborating together on this and he said he was surprised actually that no

one had ever thought of it before. He also noted that they are working very

closely with the European MSA Study Group and will be sharing information

with them.

He is most interested in getting people with clinically probable MSA and

following them for 5 years. Those who have not been given a clear clincal

diagnosis wouldn't be included in this study. They need to go with the data

they

are most sure of in order to figure out this disease. He said he'd already

received the first

batch of questionnaires in the mail on Friday.

I asked him if he thought there was already a possible treatment out there

for MSA... he said it was hard to say for sure... there are a few promising

things being tried for Parkinson's right now that could have some potential.

Clinical trials on MSA patients can't go ahead on any large scale until this

ground work is done first... i.e.. trying to better understand the mechanism

of cell death in MSA and trying to determine if there are environmental risk

factors. He stressed that they really have to proceed in a methodical

fashion so that they'd be able to determine if there is an appropriate

rationale

for trying various drugs.

He mentioned that there was still a possibility other research centers could

be added on.. it would depend on the funding.

Hugs,

Pam

MSA RESEARCH STUDY

>

>

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it.

I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I

think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

>

> Hugs,

> Pam

>

>

> Sennewald Charlottesville, Virginia

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Guest guest

-Dear Pam: I can understand why dr. shults wants study participants

with " probable " dxs. However, since I'm really struggling to get some

clarification within the next couple months (and it may happen) i'd

like to know how the study will be recruiting participants. Even if

no therapeutic interventions come out of this study, I know that

natural history studies are invaluable and utterly critical. Thanks,

Barb

-- In shydrager@y..., " Pam Bower " wrote:

> Great ! I actually just spoke with Dr. Shults on the phone.

>

> He told me a bit of the history of his group. He first proposed

forming the

> North American MSA Study Group a couple years ago at one of the

Neurology

> Society meetings. He actually got the idea from a patient with MSA

who was

> wondering why no researchers were interested in it.

>

> I told him we were thrilled that he'd got the group of researchers

> collaborating together on this and he said he was surprised

actually that no

> one had ever thought of it before. He also noted that they are

working very

> closely with the European MSA Study Group and will be sharing

information

> with them.

>

> He is most interested in getting people with clinically probable

MSA and

> following them for 5 years. Those who have not been given a clear

clincal

> diagnosis wouldn't be included in this study. They need to go with

the data

> they

> are most sure of in order to figure out this disease. He said he'd

already

> received the first

> batch of questionnaires in the mail on Friday.

>

> I asked him if he thought there was already a possible treatment

out there

> for MSA... he said it was hard to say for sure... there are a few

promising

> things being tried for Parkinson's right now that could have some

potential.

> Clinical trials on MSA patients can't go ahead on any large scale

until this

> ground work is done first... i.e.. trying to better understand the

mechanism

> of cell death in MSA and trying to determine if there are

environmental risk

> factors. He stressed that they really have to proceed in a

methodical

> fashion so that they'd be able to determine if there is an

appropriate

> rationale

> for trying various drugs.

>

> He mentioned that there was still a possibility other research

centers could

> be added on.. it would depend on the funding.

>

> Hugs,

> Pam

>

> MSA RESEARCH STUDY

> >

> >

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us

out of the

> > blue last week? I know I'm not the only one who is excited about

it.

> I've

> > heard lots of you have filled it out and sent it in. Even if you

put a NO

> > beside the question about whether you are willing or able to

travel I

> think

> > it's REALLY, REALLY important that Dr. Shults knows who you are

and where

> > you are located. We don't know for sure that those 7 centers

will be the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> >

> > Hugs,

> > Pam

> >

> >

> > Sennewald Charlottesville, Virginia 434-244-

0018

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Guest guest

I sent in mine. i am very excited about the study.

nancy m

Pam Bower wrote:

>

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it. I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

> Hugs,

> Pam

>

> If you do not wish to belong to shydrager, you may

> unsubscribe by sending a blank email to

>

> shydrager-unsubscribe

>

>

>

>

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Guest guest

I sent in mine. i am very excited about the study.

nancy m

Pam Bower wrote:

>

> I'd like to see us get back on a more positive note on the list. Remember

> the MSA/Shy-Drager research study questionnaire that came to us out of the

> blue last week? I know I'm not the only one who is excited about it. I've

> heard lots of you have filled it out and sent it in. Even if you put a NO

> beside the question about whether you are willing or able to travel I think

> it's REALLY, REALLY important that Dr. Shults knows who you are and where

> you are located. We don't know for sure that those 7 centers will be the

> only ones involved in this study. We can all make a positive contribution

> to MSA research by filling out the questionnaire.

>

> Hugs,

> Pam

>

> If you do not wish to belong to shydrager, you may

> unsubscribe by sending a blank email to

>

> shydrager-unsubscribe

>

>

>

>

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Guest guest

--- Pam:

I sent Pat's data in to Dr. Shulz and he called. I was not home but

our care-giver said he was interested. Not sure what that meant but

at least he called. Keep up the great work.

Al

> wondering why no researchers were interested in it.

>

> I told him we were thrilled that he'd got the group of researchers

> collaborating together on this and he said he was surprised

actually that no

> one had ever thought of it before. He also noted that they are

working very

> closely with the European MSA Study Group and will be sharing

information

> with them.

>

> He is most interested in getting people with clinically probable

MSA and

> following them for 5 years. Those who have not been given a clear

clincal

> diagnosis wouldn't be included in this study. They need to go with

the data

> they

> are most sure of in order to figure out this disease. He said he'd

already

> received the first

> batch of questionnaires in the mail on Friday.

>

> I asked him if he thought there was already a possible treatment

out there

> for MSA... he said it was hard to say for sure... there are a few

promising

> things being tried for Parkinson's right now that could have some

potential.

> Clinical trials on MSA patients can't go ahead on any large scale

until this

> ground work is done first... i.e.. trying to better understand the

mechanism

> of cell death in MSA and trying to determine if there are

environmental risk

> factors. He stressed that they really have to proceed in a

methodical

> fashion so that they'd be able to determine if there is an

appropriate

> rationale

> for trying various drugs.

>

> He mentioned that there was still a possibility other research

centers could

> be added on.. it would depend on the funding.

>

> Hugs,

> Pam

>

> MSA RESEARCH STUDY

> >

> >

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us

out of the

> > blue last week? I know I'm not the only one who is excited about

it.

> I've

> > heard lots of you have filled it out and sent it in. Even if you

put a NO

> > beside the question about whether you are willing or able to

travel I

> think

> > it's REALLY, REALLY important that Dr. Shults knows who you are

and where

> > you are located. We don't know for sure that those 7 centers

will be the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> >

> > Hugs,

> > Pam

> >

> >

> > Sennewald Charlottesville, Virginia 434-244-

0018

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