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Re: MSA RESEARCH STUDY

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-Dear Pam: I can understand why dr. shults wants study participants

with " probable " dxs. However, since I'm really struggling to get some

clarification within the next couple months (and it may happen) i'd

like to know how the study will be recruiting participants. Even if

no therapeutic interventions come out of this study, I know that

natural history studies are invaluable and utterly critical. Thanks,

Barb

-- In shydrager@y..., " Pam Bower " wrote:

> Great ! I actually just spoke with Dr. Shults on the phone.

>

> He told me a bit of the history of his group. He first proposed

forming the

> North American MSA Study Group a couple years ago at one of the

Neurology

> Society meetings. He actually got the idea from a patient with MSA

who was

> wondering why no researchers were interested in it.

>

> I told him we were thrilled that he'd got the group of researchers

> collaborating together on this and he said he was surprised

actually that no

> one had ever thought of it before. He also noted that they are

working very

> closely with the European MSA Study Group and will be sharing

information

> with them.

>

> He is most interested in getting people with clinically probable

MSA and

> following them for 5 years. Those who have not been given a clear

clincal

> diagnosis wouldn't be included in this study. They need to go with

the data

> they

> are most sure of in order to figure out this disease. He said he'd

already

> received the first

> batch of questionnaires in the mail on Friday.

>

> I asked him if he thought there was already a possible treatment

out there

> for MSA... he said it was hard to say for sure... there are a few

promising

> things being tried for Parkinson's right now that could have some

potential.

> Clinical trials on MSA patients can't go ahead on any large scale

until this

> ground work is done first... i.e.. trying to better understand the

mechanism

> of cell death in MSA and trying to determine if there are

environmental risk

> factors. He stressed that they really have to proceed in a

methodical

> fashion so that they'd be able to determine if there is an

appropriate

> rationale

> for trying various drugs.

>

> He mentioned that there was still a possibility other research

centers could

> be added on.. it would depend on the funding.

>

> Hugs,

> Pam

>

> MSA RESEARCH STUDY

> >

> >

> > I'd like to see us get back on a more positive note on the list.

Remember

> > the MSA/Shy-Drager research study questionnaire that came to us

out of the

> > blue last week? I know I'm not the only one who is excited about

it.

> I've

> > heard lots of you have filled it out and sent it in. Even if you

put a NO

> > beside the question about whether you are willing or able to

travel I

> think

> > it's REALLY, REALLY important that Dr. Shults knows who you are

and where

> > you are located. We don't know for sure that those 7 centers

will be the

> > only ones involved in this study. We can all make a positive

contribution

> > to MSA research by filling out the questionnaire.

> >

> >

> > Hugs,

> > Pam

> >

> >

> > Sennewald Charlottesville, Virginia 434-244-

0018

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Guest guest

> > Great ! I actually just spoke with Dr. Shults on the phone.

> >

> > He told me a bit of the history of his group. He first proposed

> forming the

> > North American MSA Study Group a couple years ago at one of the

> Neurology

> > Society meetings. He actually got the idea from a patient with

MSA

> who was

> > wondering why no researchers were interested in it.

> >

> > I told him we were thrilled that he'd got the group of researchers

> > collaborating together on this and he said he was surprised

> actually that no

> > one had ever thought of it before. He also noted that they are

> working very

> > closely with the European MSA Study Group and will be sharing

> information

> > with them.

> >

> > He is most interested in getting people with clinically probable

> MSA and

> > following them for 5 years. Those who have not been given a

clear

> clincal

> > diagnosis wouldn't be included in this study. They need to go

with

> the data

> > they

> > are most sure of in order to figure out this disease. He said

he'd

> already

> > received the first

> > batch of questionnaires in the mail on Friday.

> >

> > I asked him if he thought there was already a possible treatment

> out there

> > for MSA... he said it was hard to say for sure... there are a few

> promising

> > things being tried for Parkinson's right now that could have some

> potential.

> > Clinical trials on MSA patients can't go ahead on any large scale

> until this

> > ground work is done first... i.e.. trying to better understand

the

> mechanism

> > of cell death in MSA and trying to determine if there are

> environmental risk

> > factors. He stressed that they really have to proceed in a

> methodical

> > fashion so that they'd be able to determine if there is an

> appropriate

> > rationale

> > for trying various drugs.

> >

> > He mentioned that there was still a possibility other research

> centers could

> > be added on.. it would depend on the funding.

> >

> > Hugs,

> > Pam

> >

> > MSA RESEARCH STUDY

> > >

> > >

> > > I'd like to see us get back on a more positive note on the

list.

> Remember

> > > the MSA/Shy-Drager research study questionnaire that came to us

> out of the

> > > blue last week? I know I'm not the only one who is excited

about

> it.

> > I've

> > > heard lots of you have filled it out and sent it in. Even if

you

> put a NO

> > > beside the question about whether you are willing or able to

> travel I

> > think

> > > it's REALLY, REALLY important that Dr. Shults knows who you are

> and where

> > > you are located. We don't know for sure that those 7 centers

> will be the

> > > only ones involved in this study. We can all make a positive

> contribution

> > > to MSA research by filling out the questionnaire.

> > >

> > >

> > > Hugs,

> > > Pam

> > >

> > >

> > > Sennewald Charlottesville, Virginia 434-

244-

> 0018

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Guest guest

> > Great ! I actually just spoke with Dr. Shults on the phone.

> >

> > He told me a bit of the history of his group. He first proposed

> forming the

> > North American MSA Study Group a couple years ago at one of the

> Neurology

> > Society meetings. He actually got the idea from a patient with

MSA

> who was

> > wondering why no researchers were interested in it.

> >

> > I told him we were thrilled that he'd got the group of researchers

> > collaborating together on this and he said he was surprised

> actually that no

> > one had ever thought of it before. He also noted that they are

> working very

> > closely with the European MSA Study Group and will be sharing

> information

> > with them.

> >

> > He is most interested in getting people with clinically probable

> MSA and

> > following them for 5 years. Those who have not been given a

clear

> clincal

> > diagnosis wouldn't be included in this study. They need to go

with

> the data

> > they

> > are most sure of in order to figure out this disease. He said

he'd

> already

> > received the first

> > batch of questionnaires in the mail on Friday.

> >

> > I asked him if he thought there was already a possible treatment

> out there

> > for MSA... he said it was hard to say for sure... there are a few

> promising

> > things being tried for Parkinson's right now that could have some

> potential.

> > Clinical trials on MSA patients can't go ahead on any large scale

> until this

> > ground work is done first... i.e.. trying to better understand

the

> mechanism

> > of cell death in MSA and trying to determine if there are

> environmental risk

> > factors. He stressed that they really have to proceed in a

> methodical

> > fashion so that they'd be able to determine if there is an

> appropriate

> > rationale

> > for trying various drugs.

> >

> > He mentioned that there was still a possibility other research

> centers could

> > be added on.. it would depend on the funding.

> >

> > Hugs,

> > Pam

> >

> > MSA RESEARCH STUDY

> > >

> > >

> > > I'd like to see us get back on a more positive note on the

list.

> Remember

> > > the MSA/Shy-Drager research study questionnaire that came to us

> out of the

> > > blue last week? I know I'm not the only one who is excited

about

> it.

> > I've

> > > heard lots of you have filled it out and sent it in. Even if

you

> put a NO

> > > beside the question about whether you are willing or able to

> travel I

> > think

> > > it's REALLY, REALLY important that Dr. Shults knows who you are

> and where

> > > you are located. We don't know for sure that those 7 centers

> will be the

> > > only ones involved in this study. We can all make a positive

> contribution

> > > to MSA research by filling out the questionnaire.

> > >

> > >

> > > Hugs,

> > > Pam

> > >

> > >

> > > Sennewald Charlottesville, Virginia 434-

244-

> 0018

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