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Re: Help! confusion re: l-dopa

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Here is what the PIEN drug database has to say about Requip.

Deborah aka Tenacity

ropinerole / RequipTM

ANTIPARKINSON:

Dopamine Agonist:

Ropinirole is a potent, highly selective, dopamine agonist, not related to

pramipexole or the ergot derived drugs, developed for early therapy in

Parkinson's disease patients not yet treated with levodopa and as adjunct

therapy in treating Parkinson's disease patients not optimally controlled on

levodopa. This potent D2- dopamine agonist is active both centrally and

peripherally with central nervous system and cardiovascular activity seen.

Antidepressant and anxiolytic effects have also been noted in patients with

Parkinson's disease. Evidence of a possible neuroprotective effect has been

documented. More than 300 patients with Parkinson's disease have completed

placebo-controlled studies of ropinirole, taking doses up to 10 mg daily.

Typical dopamineric side effects such as nausea, vomiting and orthostatic

hypotension may occur at doses above 0.5 mg. Incremental dosage increases

minimize these side effects, and the drug is tolerated extremely well by the

majority of patients. A three times daily dosing schedule of lower doses

given with meals allows for fewer side effects and closer conformance to

it's half-life of 3.5-5 hours.

RequipTM has been approved by the FDA

Reply-To: shydrager

To: shydrager

Subject: Re: Help! confusion re: l-dopa

Date: Fri, 24 May 2002 22:28:25 -0000

What is Requip?

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unsubscribe by sending a blank email to

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