liver function tests

[Guest guest]

Hello everyone. Has anyone ever heard if proamatine can affect liver

function tests?

Thanks.

[Guest guest]

Greetings :

The drug manufacturer provides the following warning and caution about

proamatine:

> ProAmatineR use has not been studied in patients with

> hepatic impairment. ProAmatineR should be used with

> caution in patients with hepatic impairment, as the

> liver has a role in the metabolism of midodrine.

>

> Laboratory Tests

>

> Since desglymidodrine is eliminated by the kidneys and

> the liver has a role in its metabolism, evaluation of

> the patient should include assessment of renal and

> hepatic function prior to initiating therapy and

> subsequently, as appropriate.

So, it appears liver function tests are desirable. If liver function is

impacted, then doctors would discontinue use of proamatine. For more

information about this:

http://www.rxlist.com/cgi/generic3/midodrine_wcp.htm

Regards,

=jbf=

B. Fisher