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Re:Re: Methyl-cobalamin Question/Dinah to Kim

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Thank you so much for your help. I have not been able to determine if

methylcobalamin is stored in the body or excreted, unlike cyanocobalamin.

Further, I have just read a paper that warns against over-supplementation and in

the case of too much B12 states that the results may be dire.

http://tinyurl.com/mfwcaz

My test results were within normal limits, though somewhat on the low side.

I shall stop the injections until I am able to learn more. Any further help

would be very much appreciated.

Dinah

>

> Dinah

>

> I double-checked my latest bottle of B12 serum, and see it is cyanocabalamin.

I thought it was methylcobalamin; maybe it was at some point but since changing

primary care physicians and getting a new script it was changed and I didn't pay

enough attention. My body tolerates this new bottle of serum just as it did the

last one so I didn't check.

>

> Anyway, my experience (and my research confirms) that when your B12 levels are

low it is common to have daily or weekly injections for a period of time then

you gradually lengthen the time between shots. All depends on your initial test

result, and what other medical conditions you're dealing with. Perhaps this is

what your doctor has in mind. I have seen emails from people in my Sphincter of

Oddi dysfunction support group who need B12 injections every 3 to 5 days.

>

> But 3500mcg/day is certainly a large dose. 1000mcg/day also seems a large

dose to me when it is daily over the long-term -- but again, it depends on

whatever else is going on. Maybe methylcobalamin works differently than

cyanocobalamin, so you need more of it??

>

> I haven't done the research into whether B12 when in serum form has as high a

level of excretion as oral doses. I would guess not -- but there is bound to be

some excretion. I have interstitial cystitis (bladder lining inflammation) so

I'm very sensitive to excess B and C vitamins (and other meds., both supplement

and prescription) that end up in the bladder because so little is absorbed. I

don't experience anything after a B12 injection, other than the improvement in

my balance, coordination and muscle response. I much prefer serum injections

over oral simply because my body absorbs it better and there is less excretion.

>

> I'll do some checking. Now I'm curious to know more about this.

>

> Kim M.

>

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