Re: OT- LND, UC and sulfasalazine-help

[Guest guest]

I took it with colazal - and that's compatible, but Sulfasalazine and colazal are just forms of the same drug, and Elaine believed thatsulfasalazine was the most effective - and my experience, in retrospect, bears that up - (though I can't be sure other thingswere not effecting me at that point - so it is a personal experience, but not definitive.) Also I never experienced nausea from either one - I think if you are experiencing nausea from them, you should alert your physicianimmediately about that and get off of it. I can't imagine that is healthy to continue. What about taking rowasa enemas, which bypass the gut andgo right through the rectum to the colon. For example. MaraIs anyone taking LDN and sulfasalazine at the same time for UC? Are those compatible, or would colazal be betteI seem to be having way too much nausea and vomiting from the sulfa, is colazal less nauseaous? Unfortunately I am flaring with my UC and having major trouble keeping food down, much less digesting, so am losing weight. I know on SCD Gottschall said that azulfidine and colazal are far better options than the Asacol/Lialda mix, is the LDN interfering with the sulfa or vice versa? Any help would be appreciated. Thanks, Cathleen

[Guest guest]

Hi Cathleen,

>

> Is anyone taking LDN and sulfasalazine at the same time for UC?

Yes.

> I seem to be having way too much nausea and vomiting from the sulfa

Aside from trying Rowasa enemas or Canasa suppositories, which (as Mara

said) bypass your digestion and go straight to the colon (ideal if your

UC is mostly in the lower colon), you might also try experimenting with

the time of day you take the sulfasalazine. I didn't have any nausea the

first time I took it in 2006, but after being off it for 9 months and

restarting it this spring, I also experienced pretty serious nausea (not

to the point of vomiting, but it was NOT pleasant). I figured out that

if I didn't take it in the morning, I was fine. As long as it was lunch

or later, it didn't seem to cause the nausea. I also take it with food.

I also made some homeade ginger ale (honey, ginger and plain carbonated

water), which made me feel better.

I hope you're able to find a combination that works!

Kathy

UC since 12/05

SCD since 7/07

LDN 4.5 mg

sulfasalazine 2,000 mg/day