Guest guest Posted January 14, 2005 Report Share Posted January 14, 2005 Thanks, Barbara. I will try to digest this in the next bit of time. I am very slow putting so many different concepts into my brain. For the moment the connection I am making is maybe I can reduce my lactate load by reducing my carb intake. Overly simplistic, I am sure, but that is where I am. Again, thanks Barbara! Regards Sunny > http://tkdtutor.com/11Training/LacticAcid.htm > > http://www.cytosport.com/science/lacticacid.html > > http://members.shaw.ca/bodybuilding/Muscles/Lactic_Acid.html > > > Did a little searching this afternoon and these links and others > helped me > understand the connection between glucose and lactic acid. Note that > most of > the experts on these sites are talking about normal metabolism in > athletes, > but the basics were very helpful and there is some mention of excess > lactic > acid or lactic acidosis and one mention of mitochondria. (pasted > below) > > Most of these articles were authored by university professors, either > biochemistry or exercise physiology and the information all seemed to > jive. > So I think they are reasonably accurate. > > Several sites were trying to dispel " myths " among athletes about > lactic > acid. > > There's quite a bit about pyruvate too and its role. > > I also learned there is something called the Cori cycle whereby lactic > acid/lactate is recycled by the liver into glycogen via > gluconeogenesis. > This was one of those aha! moments because I know that > gluconeogenesis is > impaired in people with CPT deficiency. But the " backward " Cori cycle > also > allows for the utilization of carbs without a large surge of insulin. > Very > interesting. > > > Some highlights: > > The body produces lactic acid whenever it breaks down carbohydrates > for > energy. > The faster you break down glucose and glycogen the greater the > formation of > lactic acid. At rest and submaximal exercise, the body relies mainly > on fats > for fuel. However, when you reach 50% of maximum capacity, the > threshold > intensity for most recreational exercise programs, the body " crosses > over " > and uses increasingly more carbohydrates to fuel exercise. The more > you use > carbohydrates as fuel, the more lactic acid you produce. > -------------- > > Approximately 75% of the lactic acid made during exercise is used as > fuel. > The remaining 25% is converted to glucose in the kidney and liver. The > removal of accumulated lactic acid helps avert excessively high > levels, and > the conversion of lactate into glucose helps maintain sufficient > levels of > blood glucose, which is important during prolonged exercise. > ------------------------- > > Lactic acid starts to accumulate in the muscles once you start > operating > above your anaerobic threshold. This is normally somewhere between > 85% and > 90% of your maximum heart rate (MHR). > > If your lactate threshold (LT) is reached at a low exercise > intensity, it > often means that the " oxidative energy systems " in your muscles are > not > working very well. If they were performing at a high level they would > use > oxygen to break lactate down to carbon dioxide and water, preventing > lactate > from pouring into the blood. > > If your LT is low it may mean that: > > ---you are not getting enough oxygen inside your muscle cells > ---you do not have adequate concentrations of the enzymes necessary to > oxidize pyruvate at high rates > ---you do not have enough mitochondria in your muscle cells > ---your muscles, heart, and other tissues are not very good at > extracting > lactate from the blood. > ----------------------------- > > Why this backward path for liver glycogen formation? Lactate is > removed much > more rapidly from the circulatory system than glucose, which > expedites the > disposal of dietary carbohydrate without a tremendous insulin surge > and > stimulation of fat storage. > ----------------------------------- > > > > > Medical advice, information, opinions, data and statements contained > herein are not necessarily those of the list moderators. The author of > this e mail is entirely responsible for its content. List members are > reminded of their responsibility to evaluate the content of the > postings and consult with their physicians regarding changes in their > own treatment. > > Personal attacks are not permitted on the list and anyone who sends > one is automatically moderated or removed depending on the severity of > the attack. > > > > > Quote Link to comment Share on other sites More sharing options...
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