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Re: Inconclusive biopsy

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Kim

I'm sorry you hit another road block. I had several frozen biopsies

that were inconcusive. I was diagnosed without any complex I activity

on a fresh biopsy.

laurie

> Well, after waiting 6 months it appears that my second muscle biopsy

> was inconclusive. They did feel they could rule out the dozen or so

> most likely metabolic diseases. The biopsy's weren't fresh though, so

> I may have to consider Atlanta or Cleveland. Are there any good docs

> still taking patients at Cleveland?

> The doc here is still baffled why I get red urine, and I have a build

> up of pyruvate in my blood and muscle.

> I had another stroke like episode three weeks ago. I didn't go in

> though. I guess it seems senseless. Nobody seems to be able to

> figure out what I have.

> I'm not sure what to do next.

> Kim

>

>

>

>

> Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

> Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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Guest guest

May I ask how you were diagnosed? I was wondering if there was a

blood test once it was looking more like mito. I really don't want

to have to go out of state to another doc.

Kim

> > Well, after waiting 6 months it appears that my second muscle

biopsy

> > was inconclusive. They did feel they could rule out the dozen

or so

> > most likely metabolic diseases. The biopsy's weren't fresh

though, so

> > I may have to consider Atlanta or Cleveland. Are there any good

docs

> > still taking patients at Cleveland?

> > The doc here is still baffled why I get red urine, and I have a

build

> > up of pyruvate in my blood and muscle.

> > I had another stroke like episode three weeks ago. I didn't go

in

> > though. I guess it seems senseless. Nobody seems to be able to

> > figure out what I have.

> > I'm not sure what to do next.

> > Kim

> >

> >

> >

> >

> > Medical advice, information, opinions, data and statements

contained herein are not necessarily those of the list moderators.

The author of this e mail is entirely responsible for its content.

List members are reminded of their responsibility to evaluate the

content of the postings and consult with their physicians regarding

changes in their own treatment.

> >

> > Personal attacks are not permitted on the list and anyone who

sends one is automatically moderated or removed depending on the

severity of the attack.

> >

> >

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Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

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Hi Kim,

And also remember that quite a few people have had fresh muscle biopsies

done by Dr. Schoffner and they came back Negative, and he totally goes by

what the biopsy says.

But yet their Mito docs still feel and believe that they do indeed have Mito.

So it is possible that you can end up with a Negative result for your

Muscle biopsy and still have Mito.

So confusing....isn't it??

Hugs,

Ann-Marie

At 03:02 PM 6/27/2005, you wrote:

>To:

>

>Subject: Re: Inconclusive biopsy

>

>Thanks Joanne,

>It looks like I'll be able to get in with Dr. Schoffner, so I should

>probably go with it. They called me a couple weeks ago trying to

>get the rest of my records so they could schedule me. It's a long

>ways, but the testing would be over with afterwards. That sounds

>good to me. If I don't have mito, then my primary says it's

>fibromyalgia.

>Kim

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This is because he considers 5% activity or less in a complex to be a dx

of mito and other docs consider other % to be indicative of mito. At

least I believe this is how it was when my sister Laurie saw Dr.

Shoffner in 1997. Things could have changed a lot since then though.

Ann-Marie Mc wrote:

>Hi Kim,

>

>And also remember that quite a few people have had fresh muscle biopsies

>done by Dr. Schoffner and they came back Negative, and he totally goes by

>what the biopsy says.

>But yet their Mito docs still feel and believe that they do indeed have Mito.

>

>So it is possible that you can end up with a Negative result for your

>Muscle biopsy and still have Mito.

>

>So confusing....isn't it??

>

>Hugs,

>Ann-Marie

>

>

>

>

>At 03:02 PM 6/27/2005, you wrote:

>

>

>>To:

>>

>>Subject: Re: Inconclusive biopsy

>>

>>Thanks Joanne,

>>It looks like I'll be able to get in with Dr. Schoffner, so I should

>>probably go with it. They called me a couple weeks ago trying to

>>get the rest of my records so they could schedule me. It's a long

>>ways, but the testing would be over with afterwards. That sounds

>>good to me. If I don't have mito, then my primary says it's

>>fibromyalgia.

>>Kim

>>

>>

>

>

>

>

>Medical advice, information, opinions, data and statements contained herein are

not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

>Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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Ok, ya I'm totally confused now. Isn't Schoffner a mito doc? How

can it be negative and still have mito? Are there any mito docs

in/near Illinois?

My primary doc says to go with the muscle, not skin biopsy.

Kim

> >To:

> >From: " klaga5 "

> >Subject: Re: Inconclusive biopsy

> >

> >Thanks Joanne,

> >It looks like I'll be able to get in with Dr. Schoffner, so I

should

> >probably go with it. They called me a couple weeks ago trying to

> >get the rest of my records so they could schedule me. It's a long

> >ways, but the testing would be over with afterwards. That sounds

> >good to me. If I don't have mito, then my primary says it's

> >fibromyalgia.

> >Kim

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One comment here: I'm pretty sure, Dr. Shoffner will not agree to evaluate a

patietn until he has reviewed all of the available medical records and feels

reasonably certain that mitochondrial disease is one of the differential

diagnosis and a fresh biopsy is clinically indicated. Over the past 7-8 years I

can think of very, very few people that have traveled for biopsy and either

haven't proceeded or have received a negative diagnosis. At least two of those,

he did give them a diagnosis, but on biopsy findings determined that hey had

another neuromuscular disease.

dgregori@...> wrote:This is because he considers 5%

activity or less in a complex to be a dx

of mito and other docs consider other % to be indicative of mito. At

least I believe this is how it was when my sister Laurie saw Dr.

Shoffner in 1997. Things could have changed a lot since then though.

Ann-Marie Mc wrote:

>Hi Kim,

>

>And also remember that quite a few people have had fresh muscle biopsies

>done by Dr. Schoffner and they came back Negative, and he totally goes by

>what the biopsy says.

>But yet their Mito docs still feel and believe that they do indeed have Mito.

>

>So it is possible that you can end up with a Negative result for your

>Muscle biopsy and still have Mito.

>

>So confusing....isn't it??

>

>Hugs,

>Ann-Marie

>

>

>

>

>At 03:02 PM 6/27/2005, you wrote:

>

>

>>To:

>>

>>Subject: Re: Inconclusive biopsy

>>

>>Thanks Joanne,

>>It looks like I'll be able to get in with Dr. Schoffner, so I should

>>probably go with it. They called me a couple weeks ago trying to

>>get the rest of my records so they could schedule me. It's a long

>>ways, but the testing would be over with afterwards. That sounds

>>good to me. If I don't have mito, then my primary says it's

>>fibromyalgia.

>>Kim

>>

>>

>

>

>

>

>Medical advice, information, opinions, data and statements contained herein are

not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

>Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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In a message dated 6/27/2005 6:30:57 PM Eastern Standard Time,

servedogmom@... writes:

Over the past 7-8 years I can think of very, very few people that have

traveled for biopsy and either haven't proceeded or have received a negative

diagnosis. At least two of those, he did give them a diagnosis, but on biopsy

findings determined that hey had another neuromuscular disease.

Kim and others,

I went to Atlanta to see Dr Shoffner a few years ago and came back with a

negative muscle biopsy. But, I see a mito doctor in Boston who has several

hundred patients with mito and is very convinced that I still have mitochondrial

disease. Just on this last visit up to see him, I ran into 2 other people with

the same scenario. Since many of my primary symptoms are in my gut and

autonomic system, he said that we may have gotten different results if it was

possible to biopsy those organs. The reason for this is heteroplasmy which

basically means that different organs can have different amounts of defective

mitochondria. If they biopsy an area which a high percentage of bad

mitochondria, it's more likely that the person will have a positive biopsy.

Consequently,

if they biopsy an area with more good mitochondria, the biopsy may appear

normal.

My bloodwork however, shows multiple signs of mitochondrial disease,

including high alanine, high 3 methylglutaconic acid, abnormal acylcarnitines,

low

CoQ10, high lactate with acute illness, etc. But, some people with proven mito

still can have normal labwork, especially when they're not acutely ill. So

confusing, but basically it seems like there really is no one single test to

rule out mito. There are tests to rule it in and diagnose it, but no one test

to rule it out.

My mito doctor says that he often will give a clinical diagnosis of mito

based on clinical symptoms, labwork abnormalities, muscle biopsy results, and

family history. He said you have to build a case for mito and base the

diagnosis on the entire picture of what's going on.

Malisa

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Joanne,

you had mentioned Dr. Peltier to me as well and said that she could be

covered by OSF. i found that both Dr. Whiteman and Dr. Shields are on

with CCN who does out of network for OSF, but Dr. Peltier isn't

listed. any ideas why she isn't and these other two are?

kent

> There are NO competent mito docs in Illinois. If there were we

would not travel outof State with my daughters for care. The only

places in the to get a fresh muscle biopsy in the US are Cleveland and

Atlanta (my girls have had biopsies at both). Once diagnosed the

challenge is finding a competent physician for treatment (one who is

knowledgeable and supports the diagnosis). In that regard, Dr.

Peltier at Froedtert inMilwaukee is supposed to be quite good.

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In a message dated 6/27/2005 6:15:30 PM Eastern Standard Time,

klaga5@... writes:

Isn't Schoffner a mito doc? How

can it be negative and still have mito? Are there any mito docs

in/near Illinois?

Hi Kim,

As others have said, Dr Shoffner is probably one of the best doctors to go

to for a fresh muscle biopsy. Even though my biopsy was normal, I wouldn't

have gone anywhere else. Dr Shoffner primarily diagnoses patients and doesn't

typically follow them, so wouldn't be able to follow you overtime. However,

there are other doctors who specialize in mito diseases who would be able to

follow you from a distance and communicate with your primary care physician at

home. I see Dr Korson in Boston every 3 months but live in Philadelphia. Dr

K has been instrumental in guiding my doctors at home regarding how to treat

me and be proactive with my care. Before seeing Dr Korson, my doctors at

home didn't believe I had mito and had no clue what to do to help me. Even if

you have to go out of state, it's worth the trip if one of the mito doctors can

help you. Some will only have you follow up once a year but will work

closely with your doctors to manage you from a distance.

Malisa

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That's interesting. I suppose with red urine, and elevated pyruvate

in my blood, and in my muscle, it's not too difficult to assume that

something's wrong with my muscles.

Thanks for sharing that. It gives me hope that it's worth traveling

down there.

Kim

> >

> >

> >>To:

> >>From: " klaga5 "

> >>Subject: Re: Inconclusive biopsy

> >>

> >>Thanks Joanne,

> >>It looks like I'll be able to get in with Dr. Schoffner, so I

should

> >>probably go with it. They called me a couple weeks ago trying to

> >>get the rest of my records so they could schedule me. It's a

long

> >>ways, but the testing would be over with afterwards. That sounds

> >>good to me. If I don't have mito, then my primary says it's

> >>fibromyalgia.

> >>Kim

> >>

> >>

> >

> >

> >

> >

> >Medical advice, information, opinions, data and statements

contained herein are not necessarily those of the list moderators.

The author of this e mail is entirely responsible for its content.

List members are reminded of their responsibility to evaluate the

content of the postings and consult with their physicians regarding

changes in their own treatment.

> >

> >Personal attacks are not permitted on the list and anyone who

sends one is automatically moderated or removed depending on the

severity of the attack.

> >

> >

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That sounds good Kim. I hope everything goes well for you down in Atlanta.

It is a long way. I am in California and it is even longer for me, but I

would be willing to make the trip if I thought I could get some answers.

Atlanta has been very nice to work with. The little bit I have done so far.

They seem very nice.

Joanne

_____

From: [mailto: ] On Behalf

Of klaga5

Sent: Monday, June 27, 2005 12:03 PM

To:

Subject: Re: Inconclusive biopsy

Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

_____

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Guest guest

Hi ,

Do you know what the percentages are that other doctors consider to be

indicative of Mito or a dx of mito?

Just curious if all doctors are following the same technical requirements.

Thanks

Ann-Marie

At 04:53 PM 6/27/2005, you wrote:

>To:

>

>Subject: Re: Re: Inconclusive biopsy

>

>This is because he considers 5% activity or less in a complex to be a dx

>of mito and other docs consider other % to be indicative of mito. At

>least I believe this is how it was when my sister Laurie saw Dr.

>Shoffner in 1997. Things could have changed a lot since then though.

>

>

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Hi

I agree with you that Dr. Schoffner wouldn't agree to see or evaluate a

patient unless he felt that he was quite sure that Mitochondrial disease

was a possibility.

I can name more than a few that got Negative fresh biopsy results but of

course I can't identify them publically. And their Mito docs who are

treating them and caring for them are 100% sure that they have Mito.

It is just like some of the lab work that is done for Mito, sometimes it is

negative but that doesn't mean you don't have Mito. I would say the same

can be true for muscle biopsies.

Only thing I was trying to say was that she may end up with a negative

result on her muscle biopsy but that doesn't mean she doesn't have the disease.

Ann-Marie

At 06:30 PM 6/27/2005, you wrote:

>To:

>

>Subject: Re: Re: Inconclusive biopsy

>

>One comment here: I'm pretty sure, Dr. Shoffner will not agree to

>evaluate a patietn until he has reviewed all of the available medical

>records and feels reasonably certain that mitochondrial disease is one of

>the differential diagnosis and a fresh biopsy is clinically

>indicated. Over the past 7-8 years I can think of very, very few people

>that have traveled for biopsy and either haven't proceeded or have

>received a negative diagnosis. At least two of those, he did give them a

>diagnosis, but on biopsy findings determined that hey had another

>neuromuscular disease.

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Joanne if I may ask, where in California do you live? It has been a good many

years since I lived in the San Diego area but at that time Scripps Institute was

highly recommended. Off the top of my head I can't think of any other place at

the moment. I know how you feel I am stuck in Kansas and getting anywhere is a

major problem for me as I am age 69 and pretty much all alone. Dolores

Crook pjcrook@...> wrote:That sounds good Kim. I hope

everything goes well for you down in Atlanta.

It is a long way. I am in California and it is even longer for me, but I

would be willing to make the trip if I thought I could get some answers.

Atlanta has been very nice to work with. The little bit I have done so far.

They seem very nice.

Joanne

_____

From: [mailto: ] On Behalf

Of klaga5

Sent: Monday, June 27, 2005 12:03 PM

To:

Subject: Re: Inconclusive biopsy

Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

_____

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Guest guest

I know in 97' and 99' they weren't and I doubt they are today either.

That is one of the many many many difficulties with this disease. Even

the experts, few that they are, don't agree on the even the diagnostic

criteria that says " mito " !

Ann-Marie Mc wrote:

>Hi ,

>

>Do you know what the percentages are that other doctors consider to be

>indicative of Mito or a dx of mito?

>

>Just curious if all doctors are following the same technical requirements.

>Thanks

>Ann-Marie

>

>

>

>

>

>At 04:53 PM 6/27/2005, you wrote:

>

>

>>To:

>>

>>Subject: Re: Re: Inconclusive biopsy

>>

>>This is because he considers 5% activity or less in a complex to be a dx

>>of mito and other docs consider other % to be indicative of mito. At

>>least I believe this is how it was when my sister Laurie saw Dr.

>>Shoffner in 1997. Things could have changed a lot since then though.

>>

>>

>>

>>

>

>

>

>

>Medical advice, information, opinions, data and statements contained herein are

not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

>Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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Guest guest

This is true. At one point several years ago, UMDF had set up a committee of

experts from their scientific advisory board to develop standard diagnostic

criteria and lab tests/results that everyone could agree on. I know Dr.

Naviaux and Dr. Vladutiu were involved in this as well as others. Have not

heard recently if they are progressing or what, if anything, came out of

this committee.

Barbara

_____

From: [mailto: ] On Behalf

Of

Sent: Tuesday, June 28, 2005 5:26 AM

To:

Subject: Re: Re: Inconclusive biopsy

I know in 97' and 99' they weren't and I doubt they are today either.

That is one of the many many many difficulties with this disease. Even

the experts, few that they are, don't agree on the even the diagnostic

criteria that says " mito " !

Ann-Marie Mc wrote:

>Hi ,

>

>Do you know what the percentages are that other doctors consider to be

>indicative of Mito or a dx of mito?

>

>Just curious if all doctors are following the same technical requirements.

>Thanks

>Ann-Marie

>

>

>

>

>

>At 04:53 PM 6/27/2005, you wrote:

>

>

>>To:

>>

>>Subject: Re: Re: Inconclusive biopsy

>>

>>This is because he considers 5% activity or less in a complex to be a dx

>>of mito and other docs consider other % to be indicative of mito. At

>>least I believe this is how it was when my sister Laurie saw Dr.

>>Shoffner in 1997. Things could have changed a lot since then though.

>>

>>

>>

>>

>

>

>

>

>Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

>

>Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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Guest guest

Hi Dolores,

I live in northern California; Santa to be exact. It is about an hour

north of San Francisco. The closest places for me are the University of

California San Francisco, and Stanford. I have been to both places. Dr

Enns is at Stanford. I think he is more of a researcher than a clinical dr.

Of course most Mito docs are. You are right it is pretty lonely. Thank

goodness for my on-line friends!

Joanne

_____

From: [mailto: ] On Behalf

Of Dolores

Sent: Monday, June 27, 2005 7:24 PM

To:

Subject: RE: Re: Inconclusive biopsy

Joanne if I may ask, where in California do you live? It has been a good

many years since I lived in the San Diego area but at that time Scripps

Institute was highly recommended. Off the top of my head I can't think of

any other place at the moment. I know how you feel I am stuck in Kansas and

getting anywhere is a major problem for me as I am age 69 and pretty much

all alone. Dolores

Crook pjcrook@...> wrote:That sounds good Kim. I hope

everything goes well for you down in Atlanta.

It is a long way. I am in California and it is even longer for me, but I

would be willing to make the trip if I thought I could get some answers.

Atlanta has been very nice to work with. The little bit I have done so far.

They seem very nice.

Joanne

_____

From: [mailto: ] On Behalf

Of klaga5

Sent: Monday, June 27, 2005 12:03 PM

To:

Subject: Re: Inconclusive biopsy

Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

_____

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Guest guest

I will be keeping you in my thoughts and prayers. I go the 30th to see if I

have any good news as I had to have a colon biopsy and a biopsy of my esophagas

done last week. So far I have four doctors that agree on mito, but nothing

conclusive yet. I am a 69 year widow and I lost my 48 year old son 08/25/04 so

my life has been sort of up in the air but I am like a baloon loosing its air, I

usually manage to come back to earth in pretty much one piece (ha). Dolores

Crook pjcrook@...> wrote:Hi Dolores,

I live in northern California; Santa to be exact. It is about an hour

north of San Francisco. The closest places for me are the University of

California San Francisco, and Stanford. I have been to both places. Dr

Enns is at Stanford. I think he is more of a researcher than a clinical dr.

Of course most Mito docs are. You are right it is pretty lonely. Thank

goodness for my on-line friends!

Joanne

_____

From: [mailto: ] On Behalf

Of Dolores

Sent: Monday, June 27, 2005 7:24 PM

To:

Subject: RE: Re: Inconclusive biopsy

Joanne if I may ask, where in California do you live? It has been a good

many years since I lived in the San Diego area but at that time Scripps

Institute was highly recommended. Off the top of my head I can't think of

any other place at the moment. I know how you feel I am stuck in Kansas and

getting anywhere is a major problem for me as I am age 69 and pretty much

all alone. Dolores

Crook pjcrook@...> wrote:That sounds good Kim. I hope

everything goes well for you down in Atlanta.

It is a long way. I am in California and it is even longer for me, but I

would be willing to make the trip if I thought I could get some answers.

Atlanta has been very nice to work with. The little bit I have done so far.

They seem very nice.

Joanne

_____

From: [mailto: ] On Behalf

Of klaga5

Sent: Monday, June 27, 2005 12:03 PM

To:

Subject: Re: Inconclusive biopsy

Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

_____

Link to comment
Share on other sites

Guest guest

Cohen and Gold in 2001 suggested 20%.

kent

>

> Hi ,

>

> Do you know what the percentages are that other doctors consider to be

> indicative of Mito or a dx of mito?

>

> Just curious if all doctors are following the same technical

requirements.

> Thanks

> Ann-Marie

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Guest guest

Thanks Dolores

Joanne

_____

From: [mailto: ] On Behalf

Of Dolores

Sent: Tuesday, June 28, 2005 12:15 PM

To:

Subject: RE: Re: Inconclusive biopsy

I will be keeping you in my thoughts and prayers. I go the 30th to see if I

have any good news as I had to have a colon biopsy and a biopsy of my

esophagas done last week. So far I have four doctors that agree on mito,

but nothing conclusive yet. I am a 69 year widow and I lost my 48 year old

son 08/25/04 so my life has been sort of up in the air but I am like a

baloon loosing its air, I usually manage to come back to earth in pretty

much one piece (ha). Dolores

Crook pjcrook@...> wrote:Hi Dolores,

I live in northern California; Santa to be exact. It is about an hour

north of San Francisco. The closest places for me are the University of

California San Francisco, and Stanford. I have been to both places. Dr

Enns is at Stanford. I think he is more of a researcher than a clinical dr.

Of course most Mito docs are. You are right it is pretty lonely. Thank

goodness for my on-line friends!

Joanne

_____

From: [mailto: ] On Behalf

Of Dolores

Sent: Monday, June 27, 2005 7:24 PM

To:

Subject: RE: Re: Inconclusive biopsy

Joanne if I may ask, where in California do you live? It has been a good

many years since I lived in the San Diego area but at that time Scripps

Institute was highly recommended. Off the top of my head I can't think of

any other place at the moment. I know how you feel I am stuck in Kansas and

getting anywhere is a major problem for me as I am age 69 and pretty much

all alone. Dolores

Crook pjcrook@...> wrote:That sounds good Kim. I hope

everything goes well for you down in Atlanta.

It is a long way. I am in California and it is even longer for me, but I

would be willing to make the trip if I thought I could get some answers.

Atlanta has been very nice to work with. The little bit I have done so far.

They seem very nice.

Joanne

_____

From: [mailto: ] On Behalf

Of klaga5

Sent: Monday, June 27, 2005 12:03 PM

To:

Subject: Re: Inconclusive biopsy

Thanks Joanne,

It looks like I'll be able to get in with Dr. Schoffner, so I should

probably go with it. They called me a couple weeks ago trying to

get the rest of my records so they could schedule me. It's a long

ways, but the testing would be over with afterwards. That sounds

good to me. If I don't have mito, then my primary says it's

fibromyalgia.

Kim

> Kim, I am so sorry you are having all these set backs. I know

how

> you feel, because that is where I am right now. It is

frustrating!!!

> I was just wondering this morning if I had the strength to keep

> looking for my own dx. I recently had a blood test that showed

> slightly elevated ammonia levels. (this was not taken during a

crash)

> My pcp told me I should consult with dr Enns again. Dr. Enns

first

> reaction was that the lab didn't do the test right. He was a

little

> bit more interested when I told him that I had been taking sugar

free

> candy containing lactitol (which has been studied as an

alternative to

> lactulose) and that I have felt stronger. And that I also have

been

> drinking water spiked with baking soda. (If anything will help me

> avoid a crash the baking soda will. Don't ask me why.) After I

told

> him that, he asked me to get another ammonia test and blood gasses

> next time I had an attack.

> I am trying to go to see dr. Schoffner in Atlanta. My HMO is not

co-

> operating though. My pcp said we needed to get dr Enns on board

to

> help convince them. Hang in there. You are certainly not alone

in

> your quest.

> Joanne

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail

is entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with

their physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

_____

Link to comment
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