Re: I am not sure what to think

[Guest guest]

Joanne

I'm not sure how to figure the ratio, but my report from Atlanta states

that anything less than 20 is normal. My actual values were normal and I

have had one ratio that was normal.

laurie

>

> Reply-To:

> Date: Sat, 19 Feb 2005 21:01:49 -0000

> To:

> Subject: I am not sure what to think

>

>

>

> Laurie

> You mentioned the ratio between your lactic acid levels and pyruvate

> being wrong. What did you mean by that. I remembered you saying

> something like that in the past and mentioned it to Dr. Enns

> assistant. She is also a geneticist. She didn't know what I was

> talking about. My lactate levels were 1.2 and my pyruvate levels

> were .01 (which are low. The reference range is .30-.70) However

> they said that my tests all came back normal. I am confused. I

> guess I need to go for that biology degree :0)

> Joanne

>

>

>

>

>

>

> Medical advice, information, opinions, data and statements contained herein

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[Guest guest]

I was told a normal lactate/pyruvate ratio is 10 to 20 by my MDA doc,

and that above it is abnormal. Mine has been as high as 120. If the

1.2 and the 0.01 are in the same units, your ratio would be 120 as

well. I think my levels were 2.4 and 0.02.

http://www.mdausa.org/experts/question.cfm?id=3218

It's not you that needs an education as much as the nurse and the

doctors you go to. Well, that is, there is some discussion in the

medical community as to whether, IF the lactate is normal, the

lactate/pyruvate ratio is significant at all.

I guess it was in my case, since my fresh muscle biopsy showed a

significant Complex I and other defects, and my only other mito-

specific abnormal test was the lactate/pyruvate ratio. My pyruvates

have always been below normal, I think my last test was the first

time in about 10 tests that was right on the low normal number.

Perhaps it matters what type of mito defect one has - below or above

normal may be indicative of different conditions.

Take care,

RH

> Joanne

>

> I'm not sure how to figure the ratio, but my report from Atlanta

states

> that anything less than 20 is normal. My actual values were normal

and I

> have had one ratio that was normal.

>

> laurie

>

> > From: " bionicgirl_bionic "

> > Reply-To:

> > Date: Sat, 19 Feb 2005 21:01:49 -0000

> > To:

> > Subject: I am not sure what to think

> >

> >

> >

> > Laurie

> > You mentioned the ratio between your lactic acid levels and

pyruvate

> > being wrong. What did you mean by that. I remembered you saying

> > something like that in the past and mentioned it to Dr. Enns

> > assistant. She is also a geneticist. She didn't know what I was

> > talking about. My lactate levels were 1.2 and my pyruvate levels

> > were .01 (which are low. The reference range is .30-.70) However

> > they said that my tests all came back normal. I am confused. I

> > guess I need to go for that biology degree :0)

> > Joanne

> >

> >

> >

> >

> >

> >

> > Medical advice, information, opinions, data and statements

contained herein

> > are not necessarily those of the list moderators. The author of

this e mail is

> > entirely responsible for its content. List members are reminded

of their

> > responsibility to evaluate the content of the postings and

consult with their

> > physicians regarding changes in their own treatment.

> >

> > Personal attacks are not permitted on the list and anyone who

sends one is

> > automatically moderated or removed depending on the severity of

the attack.

> >

> >