Re: mitoldies: inheritance

[Guest guest]

Well, I would think it would depend on if they were sure it was

maternally transmitted in your case. I've never really heard one way or

the other. Sorry I wasn't more helpful.

MitomomX3@... wrote:

>Hi all,

>If a parent has a certain complex deficency is it assumed that the child has

>the same defect?

>Since I have a II/III defect would my kids also have a II/III defect?

>

>

>

>

[Guest guest]

It is my understanding (this might not be accurate) that if your mito is

maternally inherited, the child would have the same defect, but they

symptoms could be completely different, depending on the location of the

most damaged mito.

laurie

> From: MitomomX3@...

> Reply-To:

> Date: Sat, 19 Feb 2005 07:50:40 EST

> To:

> Subject: : inheritance

>

>

> Hi all,

> If a parent has a certain complex deficency is it assumed that the child has

> the same defect?

> Since I have a II/III defect would my kids also have a II/III defect?

>

>

>

>

[Guest guest]

I think if they do genetic testing on a parent's (or relative's)

muscle, once they define a defect, they should be able to test a

blood sample instead of having to do a muscle biopsy on each family

member. At least, that was what I was told, which is why I am

waiting for my genetic results, not for me as much as for my kids.

My uncle was another candidate for blood testing for the mutation I

have (unknown yet), but he passed away before my genetic testing was

finished.

I also think that the kids can get more or less of the " infected "

mitochondria, so if it is a mtDNA error, it may be severe or not

depending on the " mix " the child gets.

Take care,

RH

>

>

> It is my understanding (this might not be accurate) that if your

mito is

> maternally inherited, the child would have the same defect, but they

> symptoms could be completely different, depending on the location

of the

> most damaged mito.

>

> laurie

>

> > From: MitomomX3@a...

> > Reply-To:

> > Date: Sat, 19 Feb 2005 07:50:40 EST

> > To:

> > Subject: : inheritance

> >

> >

> > Hi all,

> > If a parent has a certain complex deficency is it assumed that

the child has

> > the same defect?

> > Since I have a II/III defect would my kids also have a II/III

defect?

> >

> >

> >

> >