Guest guest Posted February 16, 2005 Report Share Posted February 16, 2005 Hi all, Have any of you had acylcarnitine profiles done that were only abnormal during fasting? I have had two profiles done in the past month during 6 and 8 hrs of fasting and both were abnormal. Then, the levels were repeated on my TPN (IV nutrition) and the profile came back normal. My mito doctor says that he thinks I have a secondary fatty acid oxidation issue that occurs during fasting. He increased the amount of time I am on my TPN to 20 hrs/day. When I am off of my TPN, I start feeling really sick if I am off for more than several hours. Sometimes my blood sugar is low, but sometimes it's okay and I just feel sick all over. This has been happening more over the past year and often correlates when I am not feeling well in general. I used to be able to be off of TPN for 12 hrs without feeling badly. I can't describe how I feel when fasting, but I feel awful enough that I would go to the ER if I didn't have my TPN to hook up. Usually within 2-3 hrs of hooking up my TPN, I feel fine again. I am wondering if feeling so awful could correlate with the abnormal acylcarnitine profiles. Does anyone know if fatty acid oxidation issues can make you feel sick with only 4-6 hrs of fasting? Thanks. Malisa Quote Link to comment Share on other sites More sharing options...
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