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Imuran (azothriopine)

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Anyone here know anything about this drug or it's cousin

immunosuppressants? My concern is that it makes white blood cells

go boom, and that it may be toxic to other cells and their

components as well. I am taking it for a terrible colitis that

landed me in the hospital and was stopped by a drug called Remicade

(I was 12 hours away from losing my colon). The Imuran is being

used to both prevent creation of antibodies to the Remicade (thereby

making it ineeffective) and also help keep the colon calm. It was

very angry. I wish I knew what I did to make it so mad.

I have a partial CPT-II defect and also an adrenal disease known as

primary hyperaldosteronism. Considering the incredible physical

stress I was under, and the amount of steroids I was on in the

hospital, the fact that I didn't have myoglobinuria probably

suggests that the CPT really is partial and I problaby shouldn't

worry too much. My CO2 levels were high in the hospital, so I had

some acidosis, but considering that I hadn't really eaten in weeks,

lost 20 pounds, and had ketosis on admission, I think (I hope) that

it was due to that. Had I known at the time about it (I only got my

labs afterwards), I would have had them do a lactic acid test.

Anyway, you guys are a great group, and I'm sorry I haven't been

around. Thanks for your help!

Mike

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