Re: Q 10 absorption through skin?

[Guest guest]

In a message dated 5/28/2005 12:51:19 PM Eastern Standard Time,

lenens@... writes:

have very severe problems with my stomach and Q 10 irrtates my stomach

lining so much that I cannot tolerate it.

Does anyone know if Q10 can be absorbed through your skin if you open the

capsules and rub it into your skin, or if there is a another alternative

route to get it into your body when your stomach cannot tolerate it?

Can you get it as suppsitories?

IF there is no other alternative i might try a product without soy or soy

lecithin - does anyone know where I can get this?

Hi Lene,

I have had significant issues absorbing CoQ10 properly through my gut. We

are always trying to figure out new ways to get it to absorb. My mito doctor had

a patient who tried to get it absorbed through the skin, but his blood

levels didn't sufficiently come up when it was used this way. We looked into

CoQ10 suppositories and this can actually be done at some compounding

pharmacies. Just make sure the quality of the CoQ10 used in the suppositories is

good.

There have not been studies on how well it's absorbed though. If you try

changing the routes of administration, I would suggest getting a baseline

CoEnzyme Q10 blood level done and then rechecking it after a month of being on

the

CoQ10 to see if it rises. This can give you a good indication of whether it's

being absorbed.

Good luck!

Malisa

[Guest guest]

In a message dated 5/28/2005 12:51:19 PM Eastern Standard Time,

lenens@... writes:

have very severe problems with my stomach and Q 10 irrtates my stomach

lining so much that I cannot tolerate it.

Does anyone know if Q10 can be absorbed through your skin if you open the

capsules and rub it into your skin, or if there is a another alternative

route to get it into your body when your stomach cannot tolerate it?

Can you get it as suppsitories?

IF there is no other alternative i might try a product without soy or soy

lecithin - does anyone know where I can get this?

Hi Lene,

I have had significant issues absorbing CoQ10 properly through my gut. We

are always trying to figure out new ways to get it to absorb. My mito doctor had

a patient who tried to get it absorbed through the skin, but his blood

levels didn't sufficiently come up when it was used this way. We looked into

CoQ10 suppositories and this can actually be done at some compounding

pharmacies. Just make sure the quality of the CoQ10 used in the suppositories is

good.

There have not been studies on how well it's absorbed though. If you try

changing the routes of administration, I would suggest getting a baseline

CoEnzyme Q10 blood level done and then rechecking it after a month of being on

the

CoQ10 to see if it rises. This can give you a good indication of whether it's

being absorbed.

Good luck!

Malisa

[Guest guest]

Lene

Q-gel by Tishcon (epic4health.com) does not have soy in it. It has a

base of Vit. E. They also make a chewable kind. They are the size of a

quarter, but break into 4 parts. The total tablet contains 600 mg. so

not much is needed. This type of CoQ10 is easily absorbed, so not as

much is needed.

laurie

> I have very severe problems with my stomach and Q 10 irrtates my stomach

> lining so much that I cannot tolerate it.

> Does anyone know if Q10 can be absorbed through your skin if you open the

> capsules and rub it into your skin, or if there is a another alternative

> route to get it into your body when your stomach cannot tolerate it?

> Can you get it as suppsitories?

>

> IF there is no other alternative i might try a product without soy or soy

> lecithin - does anyone know where I can get this?

>

> Thanks in advance

> Lene

>

>

>

>

>

>

>

>

>

>

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>

[Guest guest]

In a message dated 5/29/2005 2:42:48 PM Eastern Standard Time,

lenens@... writes:

Malisa, Do you know why you don't absorb Q10 well?

What kind of Q10 do you take now?

Hi Lene,

We're not really sure why I don't absorb it well. I get most of my nutrition

intravenously due to a gut motility disorder, so it is assumed that I have

poor absorption. However, all the other meds I take seem to be absorbed just

fine. My mito doctor has seen significant absorption issues in other patients

with GI dysmotility who have mito.

I take an over the counter CoQ10 now...Sundown. However, Tishcon supposedly

has the most bioavailable (highly absorbed) CoQ10. My blood CoQ10 levels

didn't seem to improve on that brand, but many people have good luck with it. I

don't have their contact info. on me, but you may want to try Tishcon to see

if you absorb it better. The other thing is make sure whatever brand you get

is a gelcap. I have heard that the CoQ10 powder/caps get absorbed less than

the gelcaps. Have you ever had a CoQ10 level done to see how well you're

absorbing the CoQ10?

Malisa

[Guest guest]

Thanks to Laurie and Malisa for answering,

Malisa, Do you know why you don't absorb Q10 well?

What kind of Q10 do you take now?

Lene

Hi Lene,

I have had significant issues absorbing CoQ10 properly through my gut. We

are always trying to figure out new ways to get it to absorb. My mito doctor had

a patient who tried to get it absorbed through the skin, but his blood

levels didn't sufficiently come up when it was used this way. We looked into

CoQ10 suppositories and this can actually be done at some compounding

pharmacies. Just make sure the quality of the CoQ10 used in the suppositories is

good.

There have not been studies on how well it's absorbed though. If you try

changing the routes of administration, I would suggest getting a baseline

CoEnzyme Q10 blood level done and then rechecking it after a month of being on

the

CoQ10 to see if it rises. This can give you a good indication of whether it's

being absorbed.

Good luck!

Malisa

[Guest guest]

First, I'm not a medical doctor so this is only my experience, only

scientific basis is from my own little brain . I have used one

type of " by mouth " (pills) sublingually, and I found the action was

three times quicker (on average). I would venture to say that trying

to leave a chewable form under the tongue and letting it dissolve

(don't swallow or drink water) may work. It might even work with the

oil from the capsules, but it probably would taste disgusting and be

difficult to avoid swallowing it.

I had posted previously about a CoQ10 spray that is essentially the

same as sublingual (spray it in your mouth and it's absorbed by the

mucous membranes). I think this is the brand I saw:

http://www.naturesplus.com/products/category.asp?

cryteria=category&category=29&productNumber=49565

Take care,

RH

> Thanks to Laurie and Malisa for answering,

>

> Malisa, Do you know why you don't absorb Q10 well?

> What kind of Q10 do you take now?

>

> Lene

>

>

>

> Hi Lene,

> I have had significant issues absorbing CoQ10 properly through my

gut. We

> are always trying to figure out new ways to get it to absorb. My

mito doctor had

> a patient who tried to get it absorbed through the skin, but his

blood

> levels didn't sufficiently come up when it was used this way. We

looked into

> CoQ10 suppositories and this can actually be done at some

compounding

> pharmacies. Just make sure the quality of the CoQ10 used in the

suppositories is good.

> There have not been studies on how well it's absorbed though. If

you try

> changing the routes of administration, I would suggest getting a

baseline

> CoEnzyme Q10 blood level done and then rechecking it after a month

of being on the

> CoQ10 to see if it rises. This can give you a good indication of

whether it's

> being absorbed.

>

> Good luck!

> Malisa

[Guest guest]

In a message dated 5/30/2005 12:17:42 PM Eastern Standard Time,

hpone00@... writes:

I am looking into getting it in injectible form. I haven't tried it yet,

but will post when I do. You might want to try a compounding pharmacist for

this.

Hi Hazelpone,

Where are you getting the injectible form? The compounding pharmacy did say

they could make it into an IM injection but that it would be very thick and an

extremely painful injection into the muscle b/c it would contain oil. In

Japan they have or are making an IV form, but that seems to be a long ways off

for us in the US.

Malisa

[Guest guest]

Hi Lene,

I am looking into getting it in injectible form. I haven't tried it yet,

but will post when I do. You might want to try a compounding pharmacist for

this.

I thought someone told me that there was a spray, but I don't know if that

will still irritate you digestion.

I googled CO Q-10 + spray and this is one of the links I got:

http://www.genhealth.com/co.htm

Please check for quality, as I just put in the terms to see what I would get

in a search engine.

You may also want to try " patch " , I thought I saw that one too.

Also, when I tried to take COQ10 orally, I had terrible hour-on-hour

diarrhea. I know where you are coming from.

I hope this helps.

God bless,

Hazelpone

----- Original Message -----

>I have very severe problems with my stomach and Q 10 irrtates my stomach

>lining so much that I cannot tolerate it.

> Does anyone know if Q10 can be absorbed through your skin if you open

> the capsules and rub it into your skin, or if there is a another

> alternative route to get it into your body when your stomach cannot

> tolerate it?

> Can you get it as suppsitories?

>

> IF there is no other alternative i might try a product without soy or soy

> lecithin - does anyone know where I can get this?

>

> Thanks in advance

> Lene

[Guest guest]

In a message dated 5/30/2005 7:38:51 PM Eastern Standard Time,

hpone00@... writes:

I am still very new to this, but was told by " healthway pharmacy " that they

could do CO Q-10. I don't remember the pharmacist saying that it would be

in an oil form or that it would be exceptionally painful. I will call

tomorrow and check on that.

Hi Hazelpone,

If you could pass along what you find out, I would be really appreciative.

Their site looks really interesting. Thank so much!

Malisa

[Guest guest]

Hi Malisa,

I am still very new to this, but was told by " healthway pharmacy " that they

could do CO Q-10. I don't remember the pharmacist saying that it would be

in an oil form or that it would be exceptionally painful. I will call

tomorrow and check on that.

Here is there link:

http://www.healthwayrx.com/

God bless,

Hazelpone

----- Original Message -----

>

> Hi Hazelpone,

> Where are you getting the injectible form? The compounding pharmacy did

> say

> they could make it into an IM injection but that it would be very thick

> and an

> extremely painful injection into the muscle b/c it would contain oil. In

> Japan they have or are making an IV form, but that seems to be a long

> ways off

> for us in the US.

>

> Malisa

[Guest guest]

I did a search on sublingual CoQ10, and found some interesting info:

http://www.personalconsult.com/articles/coq10fibromyalgia.html

http://www.vitaminusa.com/cocq10u50sub.html

http://www.roex.com/Articles/heartsmartwithCoq10.htm

There are a few " melt " CoQ10 products out there that aren't meant for

sublingual use. BTW, I'm sure you guys know this, but remember that

sublingual tablets go directly into the bloodstream (they are not

digested), so melt/chewable tablets (or even syrups) are not

equivalent (since they are chewed and swallowed). Sublingual tablets

work *very* fast in comparison to swallowed tablets or capsules, so

if anyone takes CoQ10 " as needed " , they might want to look into

keeping the sublingual variety around. I probably mentioned already

that many medications and supplements work very slowly for me when

swallowed, so I'm always on the lookout for sublingual formulations.

Take care,

RH

>

> In a message dated 5/30/2005 7:38:51 PM Eastern Standard Time,

> hpone00@s... writes:

>

> I am still very new to this, but was told by " healthway pharmacy "

that they

> could do CO Q-10. I don't remember the pharmacist saying that it

would be

> in an oil form or that it would be exceptionally painful. I will

call

> tomorrow and check on that.

>

>

>

>

> Hi Hazelpone,

> If you could pass along what you find out, I would be really

appreciative.

> Their site looks really interesting. Thank so much!

> Malisa

>

>

>