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Hi RH,

I have been watching the posts about Ammonia levels...Mine is always

at the point of being just below the 'top of the range' with urea

usually over range...

You say you take meds for the problem..please may I ask what you

take and how effective it is..I realise that this is the Med.

prescribed for you by your Doc as his patient but it may give me

something to mention to my own Doc..

Gillian

> >

> > I too see Dr. Mark Korson since 2001. I agree..he is the BEST.

> > I have a brain injury from stroke that happened before I was

> > digignosed (spelling sorry, lost that in stroke), I was told

three

> > years after stroke that stroke was caused by MITOCHONDRIAL

DISEASE.

> >

> > Have been seeing DR.MARK (KORSON) since. He is so great with

me

> as

> > I have a harder time (damage from stroke) and Dr. Mark Korson

just

> > hangs in there with me. He stays slow...for me...and explains

> > things so that I can understand better...where as most of you

may

> > get it right away (i don't). If you can get to Boston New

England

> > Medical Center " Childrens Floating Hospital " Dr. Mark Korson is

> the

> > best. Kim Michele " KimGo'sWithFeathers "

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I take Xifaxan (rifaximin) and Lactulose. Note that people can

have " hepatic encephalopathy " (confusion etc. from high ammonia in

the blood) when ammonia levels are below the top of the range, and

other people could be fine and dandy right up until they would die

from the level (many times the max). It's definitely a YMMV thing.

When I am asymptomatic, my ammonia levels range in low normal, but

when I'm having symptoms many times per day, my ammonia is above the

high normal.

I recently went off lactulose, was fine for two weeks, then had to go

back on it, in addition to the Xifaxan.

I heartily suggest that you go to a GI specialist if at all possible,

they would do a liver panel to rule out a direct liver cause for the

lab values, and prescribe the lactulose for you if appropriate. Note

that I think there are some differences in Europe; some of the sugar

alcohols in diabetic candies in the U.S. are only prescription in

Europe (lactitol), but eating large amounts of these candies with

sugar alcohols may actually help a lot (and cause diarrhea,

essentially the mode of action for lactulose).

It causes severe diarrhea (= brown water essentially), but for me, 6

out of 7 days it is only for about 15 minutes per day, on 20 g/day.

The other day of the seven, I spend an hour or two " taking care of

business " . This happened once at my MIL's house, so of course she

thought I had food poisoning, she doesn't really recognize that I'm

ill.

I still don't understand whether the high ammonia is due to the

Complex I mito defect, or if there is another reason for it.

Take care,

RH

> > >

> > > I too see Dr. Mark Korson since 2001. I agree..he is the BEST.

> > > I have a brain injury from stroke that happened before I was

> > > digignosed (spelling sorry, lost that in stroke), I was told

> three

> > > years after stroke that stroke was caused by MITOCHONDRIAL

> DISEASE.

> > >

> > > Have been seeing DR.MARK (KORSON) since. He is so great with

> me

> > as

> > > I have a harder time (damage from stroke) and Dr. Mark Korson

> just

> > > hangs in there with me. He stays slow...for me...and explains

> > > things so that I can understand better...where as most of you

> may

> > > get it right away (i don't). If you can get to Boston New

> England

> > > Medical Center " Childrens Floating Hospital " Dr. Mark Korson

is

> > the

> > > best. Kim Michele " KimGo'sWithFeathers "

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Guest guest

I take Xifaxan (rifaximin) and Lactulose. Note that people can

have " hepatic encephalopathy " (confusion etc. from high ammonia in

the blood) when ammonia levels are below the top of the range, and

other people could be fine and dandy right up until they would die

from the level (many times the max). It's definitely a YMMV thing.

When I am asymptomatic, my ammonia levels range in low normal, but

when I'm having symptoms many times per day, my ammonia is above the

high normal.

I recently went off lactulose, was fine for two weeks, then had to go

back on it, in addition to the Xifaxan.

I heartily suggest that you go to a GI specialist if at all possible,

they would do a liver panel to rule out a direct liver cause for the

lab values, and prescribe the lactulose for you if appropriate. Note

that I think there are some differences in Europe; some of the sugar

alcohols in diabetic candies in the U.S. are only prescription in

Europe (lactitol), but eating large amounts of these candies with

sugar alcohols may actually help a lot (and cause diarrhea,

essentially the mode of action for lactulose).

It causes severe diarrhea (= brown water essentially), but for me, 6

out of 7 days it is only for about 15 minutes per day, on 20 g/day.

The other day of the seven, I spend an hour or two " taking care of

business " . This happened once at my MIL's house, so of course she

thought I had food poisoning, she doesn't really recognize that I'm

ill.

I still don't understand whether the high ammonia is due to the

Complex I mito defect, or if there is another reason for it.

Take care,

RH

> > >

> > > I too see Dr. Mark Korson since 2001. I agree..he is the BEST.

> > > I have a brain injury from stroke that happened before I was

> > > digignosed (spelling sorry, lost that in stroke), I was told

> three

> > > years after stroke that stroke was caused by MITOCHONDRIAL

> DISEASE.

> > >

> > > Have been seeing DR.MARK (KORSON) since. He is so great with

> me

> > as

> > > I have a harder time (damage from stroke) and Dr. Mark Korson

> just

> > > hangs in there with me. He stays slow...for me...and explains

> > > things so that I can understand better...where as most of you

> may

> > > get it right away (i don't). If you can get to Boston New

> England

> > > Medical Center " Childrens Floating Hospital " Dr. Mark Korson

is

> > the

> > > best. Kim Michele " KimGo'sWithFeathers "

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