Really---Really----confused

[Guest guest]

I just had a battery of tests done and I know that I do in fact have

myasthenia gravis----with the possibility of mitochondrial----My

question is what does pyruvic acid have to do with the scheme of

things---as far a mito goes------my tests keep coming back lower and

lower and Im now going a little crazy trying to figure things out---

Any help is appreciated----Thank you

Lorraine

[Guest guest]

Lorraine

My understanding is that a high pyruvate level is one to be concerned

about, although the ratio between lactate and pyruvate is also

important. I have many urine organic acids which are low or absent and

I have been told over and over not to be concerned about the low

values.

I'm sure others on the list have additional information on this for you.

laurie

>

>

> I just had a battery of tests done and I know that I do in fact have

> myasthenia gravis----with the possibility of mitochondrial----My

> question is what does pyruvic acid have to do with the scheme of

> things---as far a mito goes------my tests keep coming back lower and

> lower and Im now going a little crazy trying to figure things out---

> Any help is appreciated----Thank you

> Lorraine

>

>

>

>

>

>

> Medical advice, information, opinions, data and statements contained herein

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> is entirely responsible for its content. List members are reminded of their

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> their physicians regarding changes in their own treatment.

>

> Personal attacks are not permitted on the list and anyone who sends one is

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>

[Guest guest]

My lactic acid is either normal or high, and my pyruvate is always

very low (10 - 20% of low normal value). Others have had high

pyruvate, and been told that's a sign of mitochondrial disease. I

think it depends on which complex is damaged whether one has high or

low (or normal) pyruvate.

I was misdiagnosed with MG, I had a positive tensilon test. They did

a single fiber EMG, and that was negative and specific for MG, so

they ruled that out.

I believe both MG and mito diseases are covered by the MDA, so going

to (or staying with) a MDA clinic might be your best bet.

I also think my mito disorder is second to another disorder, but that

hasn't been proven yet, since my case is pretty odd even for mito

cases. MG is autoimmune, so perhaps you could pursue a

rheumatologist or immunologist to look into whether another

autoimmune condition could be causing mito disease.

Take care,

RH

>

> I just had a battery of tests done and I know that I do in fact

have

> myasthenia gravis----with the possibility of mitochondrial----My

> question is what does pyruvic acid have to do with the scheme of

> things---as far a mito goes------my tests keep coming back lower

and

> lower and Im now going a little crazy trying to figure things out---

> Any help is appreciated----Thank you

> Lorraine

[Guest guest]

My pyruvate is high. I know that's a concern. Low may not be.

Kim

> >

> >

> > I just had a battery of tests done and I know that I do in fact

have

> > myasthenia gravis----with the possibility of mitochondrial----My

> > question is what does pyruvic acid have to do with the scheme of

> > things---as far a mito goes------my tests keep coming back lower

and

> > lower and Im now going a little crazy trying to figure things

out---

> > Any help is appreciated----Thank you

> > Lorraine

> >

> >

> >

> >

> >

> >

> > Medical advice, information, opinions, data and statements

contained herein

> > are not necessarily those of the list moderators. The author of

this e mail

> > is entirely responsible for its content. List members are

reminded of their

> > responsibility to evaluate the content of the postings and

consult with

> > their physicians regarding changes in their own treatment.

> >

> > Personal attacks are not permitted on the list and anyone who

sends one is

> > automatically moderated or removed depending on the severity of

the attack.

> >

> >