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Hi Everyone,

A week ago I sent a fax to my wife's oncologist about the news

story that was shown in here last week about the FDA approving the

use of Xeloda for Stage 3 colon cancer patients.

Today I received a response from the oncologist that said that the

FDA had not approved it. This got the old wheels turning and I did

some research and found the letter from the FDA that " did " approve

the use of Xeloda for Stage 3 (Dukes C) colon cancer. I am going to

print the letter out and bring it to him on Thursday when my wife is

supposed to begin her regiment of Folfox 6.

If anyone is interested here is the link to the letter:

http://www.fda.gov/cder/foi/appletter/2005/020896s016ltr.pdf

Dan &

BTW. is doing fantastic right now, she is gaining weight back

and her energy level is better than before the colon resection. Of

course I am sure the chemotherapy will affect both of those, but at

least she is feeling good now.

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In a message dated 6/21/2005 11:49:31 PM Eastern Standard Time,

daniel111@... writes:

Hi Everyone,

A week ago I sent a fax to my wife's oncologist about the news

story that was shown in here last week about the FDA approving the

use of Xeloda for Stage 3 colon cancer patients.

Today I received a response from the oncologist that said that the

FDA had not approved it. This got the old wheels turning and I did

some research and found the letter from the FDA that " did " approve

the use of Xeloda for Stage 3 (Dukes C) colon cancer. I am going to

print the letter out and bring it to him on Thursday when my wife is

supposed to begin her regiment of Folfox 6.

If anyone is interested here is the link to the letter:

http://www.fda.gov/cder/foi/appletter/2005/020896s016ltr.pdf

Dan &

BTW. is doing fantastic right now, she is gaining weight back

and her energy level is better than before the colon resection. Of

course I am sure the chemotherapy will affect both of those, but at

least she is feeling good now.

Way to keep on top of those doctors, Dan!!! Love the way you are fighting

for your beautiful wife. So glad she's feeling good right now...enjoy!!! The

chemo will probably zap her some, but she sounds strong and determined and

quite the little fighter!!! Tell her we are praying for both of you!!! Hang

on tight... the roller coaster ride has begun!!!

Lots of hugs and prayers, Donelle

Caregiver to Glenn

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I opened the letter, and what I am understanding is that it has been approved

for Stage III when " This new drug application provides for the use of XELODA

(Capcitabine) oral tablets as a single agent

for adjuvant treatment in patients with Dukes’ C colon cancer who have undergone

complete resection

of the primary tumor when treatment with fluoropyrimidine therapy alone is

preferred. "

I have not heard of any on the list getting a single agent therapy for first

line chemo in a while. They are getting 5FU, Leucovorin, and Oxaliplatin.

Personally, I believe the Oxaliplatin is offering additional benefits over 5FU

and Leucovorin. I believe the research supports this as well. FDA approved

adding Oxaliplatin to the 5FU regimen in November of 2004 for Stage III.

MA

>

>

> Date: 2005/06/21 Tue PM 11:48:28 EDT

> To: colon_cancer_support

> Subject: Xeloda

>

>

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Donelle,

Thank you so much. is a fighter. She may only be 4'9 " tall

and 75 lbs, but she tougher than hell and she'll let you know it

too.

As for the doctors, if I didn't do the research into the terms that

they use so frequently (to sound intelligent if you ask me) then we

wouldn't have a clue what was going on. We recently got copies of

all of 's medical records and starting reading and researching

everything. So far what they have done is standard operating

procedures so we are not yet worried, okay maybe a little.

Chemo starts tomorrow and I've got every finger and toe crossed

hoping for the best, but will be ready for the worst. I'm here for

the long haul...

Our prayers go out to you and Glenn. Keep up the good fight!

Dan &

>

>

> In a message dated 6/21/2005 11:49:31 PM Eastern Standard Time,

> daniel111@c... writes:

>

> Hi Everyone,

>

> A week ago I sent a fax to my wife's oncologist about the news

> story that was shown in here last week about the FDA approving the

> use of Xeloda for Stage 3 colon cancer patients.

>

> Today I received a response from the oncologist that said that the

> FDA had not approved it. This got the old wheels turning and I

did

> some research and found the letter from the FDA that " did " approve

> the use of Xeloda for Stage 3 (Dukes C) colon cancer. I am going

to

> print the letter out and bring it to him on Thursday when my wife

is

> supposed to begin her regiment of Folfox 6.

>

> If anyone is interested here is the link to the letter:

>

> http://www.fda.gov/cder/foi/appletter/2005/020896s016ltr.pdf

>

> Dan &

>

> BTW. is doing fantastic right now, she is gaining weight

back

> and her energy level is better than before the colon resection.

Of

> course I am sure the chemotherapy will affect both of those, but

at

> least she is feeling good now.

>

>

>

>

>

> Way to keep on top of those doctors, Dan!!! Love the way you are

fighting

> for your beautiful wife. So glad she's feeling good right

now...enjoy!!! The

> chemo will probably zap her some, but she sounds strong and

determined and

> quite the little fighter!!! Tell her we are praying for both of

you!!! Hang

> on tight... the roller coaster ride has begun!!!

>

> Lots of hugs and prayers, Donelle

> Caregiver to Glenn

>

>

>

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