Re: My Dad -- Avastin and protein levels in urine???? JOE

[Guest guest]

I'm definitely not an oncologist or surgeon so my opinion is worth

absolutely nothing. Nevertheless, here it is.

Colon cancer is nasty. One or two cells floating around can stop and

create a lesion at a site, and pretty soon you have another " met " .

Trying to remove multiple or diffuse malignancies in the abdomen

runs the risk of knocking some more cells free and letting them

loose in the abdomen, or worse, the blood stream.

If the cells are encapsulated in a tumor, the surgeon can cut the

tumor out and take all of the cancer at that time. The chances of

having free adenocarcinoma cells floating around are pretty small,

so it is a good bet.

Messing around in the abdomen is not much fun, and runs some serious

risks, including possible adhesions, small bowel perforation, etc.

Also, any surgery would delay your dad's chemotherapy since it's not

a good idea to keep taking that stuff when you are weak from

surgery. In fact, some drugs, like Avastin, will cause your wounds

from surgery to open up instead of healing (wound dehissance).

So, my opinion, being totally worthless of course, is that your

oncologist is right. Keep trying the conservative approach of Xeloda

and good living. Maybe some nutritional supplements to keep his

strength up would be a good idea.

Meanwhile, today I leave for a week in the Yucatan area of Mexico

with my daughter. I'm leaving my colon cancer behind for a week or

so, just to have fun. When I get back I'll start my clinical trial

on a new drug that may be the " magic bullet " that kicks colon

cancer. Wish me luck.

-joe-

> > > We have bad news today -- my dad's Avastin chemo

> > was

> > > cancelled because of high protein levels (3+) in

> > his

> > > urine.

> > >

> > > He MRI results (as compared to 12/03 and 9/04)

> > showed

> > > sligh increases in the size of his peritoneal mets

> > > (largest from 8 cm to 10 cm) and they found

> > another

> > > smaller met in the mid-abdomen near the transverse

> > > colon (about 2 cm). The lung mets are the same.

> > >

> > > His Onc says that my dad's tumors seem to be slow

> > > growing so that's good news. His liver, kidneys,

> > etc.

> > > are fine.

> > >

> > > My dad has been experiencing more abdominal pain

> > near

> > > his right side where the mets are.

> > >

> > > Is there anything medications or anything that we

> > can

> > > do to help reduce the protein levels in his

> > urine???

> > >

> > >

> > > I am praying this protein level decreases so he

> > can

> > > re-start Avastin treatment again.

> > >

> > > Any suggestions would be greatly appreciated.

> > >

> > > Have a nice July 4th weekend.

> > >

> > > Nickie

> > >

> > >

> > >

> > > __________________________________

> > > Discover Yahoo!

> > > Have fun online with music videos, cool games, IM

> > and more. Check

> > it out!

> > > http://discover.yahoo.com/online.html

> >

> >

> >

>

>

> __________________________________________________

>

[Guest guest]

Joe,

Thank you for your advice. I hope you and your

daughter have a great trip to Mexico!!!!

Please keep us posted on your trial too.

Colon cancer may ravage our bodies and our loved ones'

bodies, but I know it will never take away a person's

spirit.

Have a great vacation!!!!

Nickie

--- Joe Savage JSAVAGE@...> wrote:

> I'm definitely not an oncologist or surgeon so my

> opinion is worth

> absolutely nothing. Nevertheless, here it is.

>

> Colon cancer is nasty. One or two cells floating

> around can stop and

> create a lesion at a site, and pretty soon you have

> another " met " .

> Trying to remove multiple or diffuse malignancies in

> the abdomen

> runs the risk of knocking some more cells free and

> letting them

> loose in the abdomen, or worse, the blood stream.

>

> If the cells are encapsulated in a tumor, the

> surgeon can cut the

> tumor out and take all of the cancer at that time.

> The chances of

> having free adenocarcinoma cells floating around are

> pretty small,

> so it is a good bet.

>

> Messing around in the abdomen is not much fun, and

> runs some serious

> risks, including possible adhesions, small bowel

> perforation, etc.

> Also, any surgery would delay your dad's

> chemotherapy since it's not

> a good idea to keep taking that stuff when you are

> weak from

> surgery. In fact, some drugs, like Avastin, will

> cause your wounds

> from surgery to open up instead of healing (wound

> dehissance).

>

> So, my opinion, being totally worthless of course,

> is that your

> oncologist is right. Keep trying the conservative

> approach of Xeloda

> and good living. Maybe some nutritional supplements

> to keep his

> strength up would be a good idea.

>

> Meanwhile, today I leave for a week in the Yucatan

> area of Mexico

> with my daughter. I'm leaving my colon cancer behind

> for a week or

> so, just to have fun. When I get back I'll start my

> clinical trial

> on a new drug that may be the " magic bullet " that

> kicks colon

> cancer. Wish me luck.

>

> -joe-

>

>

>

> > > > We have bad news today -- my dad's Avastin

> chemo

> > > was

> > > > cancelled because of high protein levels (3+)

> in

> > > his

> > > > urine.

> > > >

> > > > He MRI results (as compared to 12/03 and 9/04)

> > > showed

> > > > sligh increases in the size of his peritoneal

> mets

> > > > (largest from 8 cm to 10 cm) and they found

> > > another

> > > > smaller met in the mid-abdomen near the

> transverse

> > > > colon (about 2 cm). The lung mets are the

> same.

> > > >

> > > > His Onc says that my dad's tumors seem to be

> slow

> > > > growing so that's good news. His liver,

> kidneys,

> > > etc.

> > > > are fine.

> > > >

> > > > My dad has been experiencing more abdominal

> pain

> > > near

> > > > his right side where the mets are.

> > > >

> > > > Is there anything medications or anything that

> we

> > > can

> > > > do to help reduce the protein levels in his

> > > urine???

> > > >

> > > >

> > > > I am praying this protein level decreases so

> he

> > > can

> > > > re-start Avastin treatment again.

> > > >

> > > > Any suggestions would be greatly appreciated.

> > > >

> > > > Have a nice July 4th weekend.

> > > >

> > > > Nickie

> > > >

> > > >

> > > >

> > > > __________________________________

> > > > Discover Yahoo!

> > > > Have fun online with music videos, cool games,

> IM

> > > and more. Check

> > > it out!

> > > > http://discover.yahoo.com/online.html

> > >

> > >

> > >

> >

> >

> > __________________________________________________

> >