Re: Thyroglobulin-Thyroxine? Elaine/anyone-advice please

[Guest guest]

Hi,

With your TSH being higher than you want, I'd reduce your dose.

Your doctor is confused re the test.

Thyroxine binding globulin (TBG) is a protein that transports thyroid hormone

throughout the blood. While antibodies are also proteins (immunoglobulin

proteins), TBG is not an antibody.

None of your results are for a TSI, although the TBII tests measures all the

TSH receptors that bind to the TSH receptor. So it measures both stimulating

and blocking TSH receptor antibodies. And TSI (thyroid stimulating

immunoglobulins) are the same as stimulating TSH receptor antibodies. It

would be better, though, to have a TSI than a TBII to predict remission. Take

care, Elaine

[Guest guest]

Hi,

With your TSH being higher than you want, I'd reduce your dose.

Your doctor is confused re the test.

Thyroxine binding globulin (TBG) is a protein that transports thyroid hormone

throughout the blood. While antibodies are also proteins (immunoglobulin

proteins), TBG is not an antibody.

None of your results are for a TSI, although the TBII tests measures all the

TSH receptors that bind to the TSH receptor. So it measures both stimulating

and blocking TSH receptor antibodies. And TSI (thyroid stimulating

immunoglobulins) are the same as stimulating TSH receptor antibodies. It

would be better, though, to have a TSI than a TBII to predict remission. Take

care, Elaine

[Guest guest]

Thanks Elaine.

> None of your results are for a TSI,

Now I'm confused again...are you saying that not even the first

results, done in April are for TSI?

April, 2002 labs:

Thyroglobulin AB >3000 H Range 1-121

Thyroid Peroxidase AB 1081 H

Thyrotropin Bind Immuno >40

Theraputic Range:

Less than 1.0

Borderline: 1.0-2.0

Elevated: Greater than 2.0

Lori

[Guest guest]

Hi,

The thyrotropin binding inhibiting immunoglobulins (TBII) include a

measurement of TSI as well as any other TSH receptor antibodies that bind to

the TSH receptor.

Although the test isn't specific for TSI, if you're hyperthyroid you can

assume that most of the TBII are TSI. And if you had also had a test for

blocking TSH receptor antibodies and it was negative, you would know that all

the TBII present were TSI.

Having TSH receptor antibodies (the TBII) as well as the other thyroid

antibodies along with hyperthyroidism confirms Graves' disease. Take care,

Elaine