Aloe Vera- From Sloan Kettering Cancer Center

[Guest guest]

Bottom Line: Aloe is safe to use topically for treating skin conditions such

as minor burns, psoriasis, and side effects of radiation therapy, although

it may not work for everyone. Aloe is NOT an effective cancer treatment and is

dangerous when given by injection.

Scientists think that compounds found in aloe inhibit molecules that play a

role in inflammation. Studies in laboratory rats confirm this

anti-inflammatory activity. Aloe is also thought to hinder the formation of

thromboxane, a

molecule that is detrimental to the healing of burn wounds. Aloe kills

bacteria and fungi directly in laboratory studies. Aloe vera gel should not be

confused with aloe juice or aloe latex, both of which contain potent laxative

substances.

PURPORTED USES

As a topical anesthetic

Laboratory evidence supports this use, but it has not been tested in

clinical trials.

To treat burns

Scientific evidence supports the topical use of aloe for minor burns.

To prevent and treat redness, rash, and pruritus caused by radiation therapy

Clinical trials have produced conflicting results in support of and against

this use. Topical use of aloe is generally safe.

As a skin moisturizer

No scientific evidence supports this use. Topical use of aloe is generally

safe.

To treat inflammation associated with conditions such as cold sores, eczema,

and pruritis

Clinical evidence supports this use.

To treat cancer

No scientific evidence supports this use. Cancer therapy using injections of

acemannan, a substance found in aloe, resulted in the deaths of several

patients.

To treat diabetes

Two nonrandomized trials by the same investigator group suggest that blood

glucose levels may be reduced by aloe vera. Further study is warranted.

To treat ulcerative colitis

A small randomized, controlled trial shows weak support for this use.

Further study is warranted.