Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Thanks ...an interesting read. I hope YOU are doing "ok".... God Bless! MamaSher; 70, IPF 3-06, OR. NasturtiumsDon't fret about tomorrow, God is already there! R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially," she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system-lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/ and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical.NetNews-Medical.Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech.com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Absolutely fascinating article , thanks for posting it. Much food for thought! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: pulumonary Fibrosis <breathe-support >Sent: Wednesday, March 25, 2009 12:34:44 PMSubject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/pulmonary/clinics/interstitial_lung_disease.html and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially," she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system-lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/ and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical.NetNews-Medical.Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech.com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially," she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system-lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/ and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical.NetNews-Medical.Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech.com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially," she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system-lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/ and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical.NetNews-Medical.Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech.com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Beth, No I am not on O2 because when I am up moving my SATs rise and that is when he sees me. I would call him if he weren't on vacation the whole month of March. Must be nice! At least now I know why I am so fatigued in the morning. Sunny, IPF, 09, WA From: Beth Sent: Wednesday, March 25, 2009 11:03 AM To: Breathe-Support Subject: Re: R.E.M. sleep Sunny, Forgive my lousy memory but are you currently on O2? If not you should definitely call your pulmo with the information that you are satting below 90 upon waking up in the morning. Don't wait for your next appointment. If you are currently on O2, you may need it set a bit higher when you sleep to keep your sats up. Again check with your doctor but don't let this go. Low sats over long periods of time (like when you sleep at night) cause damage that can be easily prevented! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: "rpickel1 (AT) msn (DOT) com" <rpickel1 (AT) msn (DOT) com>To: Breathe-Support Sent: Wednesday, March 25, 2009 1:43:39 PMSubject: Re: R.E.M. sleep Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsm edicine.org/ and http://www.chestjou rnal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Sunny did they do that overnight oximeter test? don't remember if you are using O2, if not, sounds like you need to sleep with it discuss this with your doc Pink Joyce IPF 3/06 Pennsylvania Donate Life Listed 1/09 www.transplantfund.org--- Subject: Re: R.E.M. sleepTo: Breathe-Support Date: Wednesday, March 25, 2009, 1:43 PM Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsm edicine.org/ and http://www.chestjou rnal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Sunny did they do that overnight oximeter test? don't remember if you are using O2, if not, sounds like you need to sleep with it discuss this with your doc Pink Joyce IPF 3/06 Pennsylvania Donate Life Listed 1/09 www.transplantfund.org--- Subject: Re: R.E.M. sleepTo: Breathe-Support Date: Wednesday, March 25, 2009, 1:43 PM Thanks for this interesting information. Someone wonderful sent me an O2 monitor. In the morning on first waking up my SATs are well below 90 but after moving around they come back up to 94. I also suffer from severe fatigue. My pulmo guy just saw my SATs in the afternoon so he isn't worried. I am only hoping he will take me serious when I see him again in April. Does anyone else have extremely low SATs in the morning? Mine are way worse on my back or laying on my right side. I also have stopped eating for almost three weeks. Just an occasional very small meal every other evening or so. Is this part of IPF? Sunny, IPF, 09, WA From: Sent: Wednesday, March 25, 2009 9:34 AM To: pulumonary Fibrosis Subject: R.E.M. sleep Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsm edicine.org/ and http://www.chestjou rnal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Joyce, Here is the link to the article referenced. http://www.news-medical.net/?id=40372 Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Wednesday, March 25, 2009 7:44:39 PMSubject: Re: R.E.M. sleep thanks for this article unfortunately the right side of it was cut off would it be possible to either resend it or send a link thank you very much Pink Joyce IPF 3/06 Pennsylvania Donate Life Listed 1/09 www.transplantfund. org From: <kpoooh9 (AT) yahoo (DOT) com>Subject: R.E.M. sleepTo: "pulumonary Fibrosis" <breathe-support@ yahoogroups. com>Date: Wednesday, March 25, 2009, 12:34 PM Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsmedicine.org/pulmonary/clinics/interstitial_lung_disease.html and http://www.chestjournal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 http://www.news-medical.net/?id=40372good search site for other fibrosis stuffhttp://www.news-medical.net/?keyword=Pulmonary%20fibrosis P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. From: <kpoooh9 (AT) yahoo (DOT) com>Subject: R.E.M. sleepTo: "pulumonary Fibrosis" <breathe-support@ yahoogroups. com>Date: Wednesday, March 25, 2009, 12:34 PM Researchers link the extreme fatigue in pulmonary fibrosis to loss in body-rejuvenating R.E.M. sleep Published: Tuesday, 29-Jul-2008 Printer Friendly Medical Condition News Family, friends and neighbors remember Sandler Spaeth as an active mother of two in Potomac, Md., with a lot on the go, juggling her son's baseball games and her daughter's horseback-riding lessons with numerous committee obligations, organizing women's activities at her local synagogue. Add to this Spaeth's thriving home business turned wholesale supplier - making custom hair accessories for children - which she founded with her mother. But Spaeth was also diagnosed with pulmonary fibrosis, a hard-to-treat disease that progressively damages the lungs and starves the body of oxygen. For two years after her diagnosis, until her death in May 2007, at age 44, Spaeth was beset by fatigue. Her energy levels sank as her lungs deteriorated. Breathing became difficult, and she could no longer attend many of the sporting events, trade fairs and women's groups that filled her life. It is with people like Spaeth in mind that researchers at s Hopkins and elsewhere have found what is likely to be the first evidence linking the extreme fatigue in the lung-scarring disease, which has no known cause, to the poor quality of sleep that results - as much as a 25 percent loss in body-rejuvenating R.E.M. sleep. And they have also gauged the detrimental effects this has on people's daily lives, nearly halving test scores used to assess physical and mental quality of life. In a report appearing this month in the journal Chest, senior study investigator and pulmonologist Sonye Danoff, M.D., Ph.D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the s Hopkins University School of Medicine. The latest study results back up previous research by Danoff and other sleep experts at s Hopkins, which showed that 18 of 22 people with fibrosed lungs had problems breathing while asleep. The majority of them dropped out of R.E.M. sleep during the night, losing 25 percent of total R.E.M. sleep time. It is during the R.E.M. period that rapid eye movements occur (hence the name), that people dream and that the body recovers from the previous day and builds up energy for the next. Pulmonary fibrosis makes people highly vulnerable to sleep problems, Danoff says, because they often breathe twice as fast to supply the body with oxygen. And just as breathing and other body functions naturally slow down at the onset of R.E.M. sleep, these people who depend on a higher rate of breathing are constantly being pushed to wake up from a lack of oxygen. "Essentially, " she adds, "the body's internal alarms go off as people enter the most rejuvenating part of sleep. And when people don't get a good night's sleep, they cannot function normally the next day. It's a slippery slope that gets progressively worse over time." Also in this latest s Hopkins study are survey results assessing quality of life and quality of sleep, which showed that people with stiffened lungs and sleep problems have 40 percent lower scores in physical activities compared to the general U.S. population. Rated activities included basic tasks, such as going to the mailbox and walking to the car. Mental and social activities, such as carrying on a conversation with a store clerk or telephoning friends and family, were reduced 48 percent. Sleep quality was assessed on a scale comprising 36 different sleep measurements, such as the length of time it took to fall asleep and overall time spent sleeping. Moreover, the team's analysis showed that sleep problems could not be predicted by other demographic factors, such as age, gender, race or weight. Nor were they linked, researchers say, with other lung function and more noticeable disease symptoms, including shortness of breath and cough. "Because there is so much about pulmonary fibrosis that we cannot yet fix, we need to focus on what we can fix while we wait for research to catch up with treatments that can prevent or reverse the disease," says Danoff. Current treatments for pulmonary fibrosis are limited to steroids and other immune-system- lowering drugs that help slow down lung tissue deterioration as the thin walls of the air sacs stiffen and lose capacity to freely expand and contract. More than 200,000 Americans suffer from pulmonary fibrosis, whose cause remains unknown. And the lung disease kills nearly 40,000 each year. "If we had been able to treat Spaeth's fatigue from poor quality sleep, then she might have had more time to lead her life as fully as she had been prior to getting sick," says Danoff. Despite Spaeth's death, her zest for life carries on. Her mother, Froma Sandler, maintains the business. And through the encouragement of family and friends, more than a thousand people have donated to medical research in Spaeth's honor. The largest-ever contributions arrived in May, just prior to the first anniversary of Spaeth's death, when the land-based M. Fisher Memorial Foundation pledged $2 million to s Hopkins to help fund Danoff's future studies into pulmonary disease. "This research funding will lay the groundwork for a more consolidated and comprehensive look at the many factors that may improve and extend the lives of patients with pulmonary fibrosis: from rehabilitation of the lungs to the development and testing of new medications to offset losses in quality of life from fatigue," says Danoff. Danoff plans to use some of the funding to support studies that monitor patients with pulmonary fibrosis for problems in sleep patterns, especially in deep-sleep R.E.M. patterns, to target for treatment. Another phase of research, she says, involves testing new devices to support breathing during sleep and to see if these devices improve quality sleep time and abate fatigue. Funding for this latest study was provided by a fellowship grant from the CHEST Foundation, the philanthropic arm of the American College of Chest Physicians, which also publishes the journal Chest, and by The s Hopkins Hospital's General Clinical Research Center. In addition to Danoff, other Hopkins researchers involved in these studies, conducted solely in Balimore, were Vidya Krishnan, M.D.; Meredith McCormack, M.D., M.H.S.; Mathai, M.D., M.H.S.; Maureen Horton, M.D.; and Collop, M.D. Additional assistance was provided by Shikhar Agarwal, M.D., from the s Hopkins University's Bloomberg School of Public Health; Brittany , from the University of land; and Albert Polito, M.D., from Mercy Medical Center. http://www.hopkinsm edicine.org/ and http://www.chestjou rnal.org/ Child Health > Disease > Technology > Health Care > Conditions > Procedures > Patents > Research > Men's Health > Science > Miscellaneous > Pharmaceutical > Drug Trials > Women's Health > News-Medical.Net provides this medical news service in accordance with these terms and conditions. Please note that medical information found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide. Version 2.0 Copyright © 2009 News-Medical. NetNews-Medical. Net - AZoNetwork | Suite 24 | 90 Mona Vale Rd | Mona Vale | NSW 2102 | Australia Other AZoNetwork Sites | AZoM.com | AZoBuild.com | AZoOptics.com | AZoNano.com | AZoCleantech. com P PM (Polymositis) 12/98, UIP 8/00, o2 24/7 9 LPM 8/04, PH 3/06, ILL yo 60REMEMBER : All of you on Prednisone'stressed' spelled backwards is 'desserts'If God brings you to it - He will bring you through it. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.