Guest guest Posted November 27, 2007 Report Share Posted November 27, 2007 > I have fast Phase 1, normal Phase 2 pathways according to the Great > Smokies lab test. Do I want to slow down Phase 1 and why, and if so, > using what? Sam-e, niacinamide or grapefruit seed extract, or something > else? What is the impact on the body of all this? Less intermediate toxins? > Thanks, Mark Mark my understanding is that niacinamide and grapefruit seed extract and grapefruit juice slow down phase 1 which slows down the metabolism of your liver so that toxins get removed/cleansed more efficiently I think Sam-e is a NO NO (not 100% on this though, you may want to use the search tool on this site. It really helps me to review past posts) I know a lot of med journals mention to be careful with grapefruit juice when taking meds as I think the slower metabolism caused by the grapefruit, will enhance the impact of the medication I have fast phase 1-slow phase 2 and I believe these two items (grapefruit seed/juice and niacinamide) have really helped with calming my MCS (mult chem sensitivities) down Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 > > I have fast Phase 1, normal Phase 2 pathways according to the Great > > Smokies lab test. Do I want to slow down Phase 1 and why, and if so, > > using what? Sam-e, niacinamide or grapefruit seed extract, or > something > else? What is the impact on the body of all this? Less > intermediate toxins? > > Thanks, Mark > > > Mark my understanding is that niacinamide and grapefruit seed extract > and grapefruit juice slow down phase 1 which slows down the metabolism > of your liver so that toxins get removed/cleansed more efficiently > I think Sam-e is a NO NO (not 100% on this though, you may want to use > the search tool on this site. It really helps me to review past posts) > > I know a lot of med journals mention to be careful with grapefruit > juice when taking meds as I think the slower metabolism caused by the > grapefruit, will enhance the impact of the medication > > I have fast phase 1-slow phase 2 and I believe these two items > (grapefruit seed/juice and niacinamide) have really helped with calming > my MCS (mult chem sensitivities) down > TopBroker, What are you taking dosage-wise of these two and do you also take anything to counteract the digestive impact of the grapefruit product? Mark Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 > > I have fast Phase 1, normal Phase 2 pathways according to the Great > > Smokies lab test. Do I want to slow down Phase 1 and why, and if so, > > using what? Sam-e, niacinamide or grapefruit seed extract, or > something > else? What is the impact on the body of all this? Less > intermediate toxins? > > Thanks, Mark > > > Mark my understanding is that niacinamide and grapefruit seed extract > and grapefruit juice slow down phase 1 which slows down the metabolism > of your liver so that toxins get removed/cleansed more efficiently > I think Sam-e is a NO NO (not 100% on this though, you may want to use > the search tool on this site. It really helps me to review past posts) > > I know a lot of med journals mention to be careful with grapefruit > juice when taking meds as I think the slower metabolism caused by the > grapefruit, will enhance the impact of the medication > > I have fast phase 1-slow phase 2 and I believe these two items > (grapefruit seed/juice and niacinamide) have really helped with calming > my MCS (mult chem sensitivities) down > TopBroker, What are you taking dosage-wise of these two and do you also take anything to counteract the digestive impact of the grapefruit product? Mark Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 > What are you taking dosage-wise of these two and do you also take > anything to counteract the digestive impact of the grapefruit product? > Mark I take ** 1500 mgs 3 times a day of the niacinamide and have found that less does not work as well ** had been taking a glass of Grapefruit juice 3 times aday with food and other supplements...just started on the capsules of grapefruit seed extract 125 mg 3times a day ** I also take 100 mg selenomethionine 3 times aday. Andy says these three help with MCS and they realy have calmed things down in my anxiety, fatigue and other problems with fumes I haven't had any problems with the grapefruit juice. I use it also to clean my vegetables for juicing. Historically I have had a cast iron stomach (up until the last 3 years anyway) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 > What are you taking dosage-wise of these two and do you also take > anything to counteract the digestive impact of the grapefruit product? > Mark I take ** 1500 mgs 3 times a day of the niacinamide and have found that less does not work as well ** had been taking a glass of Grapefruit juice 3 times aday with food and other supplements...just started on the capsules of grapefruit seed extract 125 mg 3times a day ** I also take 100 mg selenomethionine 3 times aday. Andy says these three help with MCS and they realy have calmed things down in my anxiety, fatigue and other problems with fumes I haven't had any problems with the grapefruit juice. I use it also to clean my vegetables for juicing. Historically I have had a cast iron stomach (up until the last 3 years anyway) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 3, 2007 Report Share Posted December 3, 2007 sorry to not respond earlier. I have been travelling and starting dmsa rounds and it has been quite unpleasant niacinamide actually was at 1500 mgs (3x a day) so I guess thats 4.5 grams. Now I am down to 3000 (1000 3x a day). When I first started, 3000 didn't do it for me selenomethionine 100mcg 3 x a day. I think AI says not to go over 300 grapefruit juice. I was buying organic jugs, not juicing my own...I should probably consider that when they are in season. I have now started on the grapefruit seed extract (3 times 125 mg) I think this combination has at least allowed me to function on a nominal level. Before the fumes in the city would make me very anxious, depressed , agitated and physically ill > Hi > You take 4 and a half grams of niacinamide a > day? just checking, and do you juice your own grapefruit. > I have been taking one small glass a day of the juice because > the organic fruits are so expensive... and the selenium... is that > 100mgs or 100 mcgs? > > good to hear that it's working for you > I have noticed some improvement with sensitivities, but I also > think I don't react as severely as some others. I also take NAC. > deborah Quote Link to comment Share on other sites More sharing options...
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