Does DMSA Cross Brain Barrier?

[Guest guest]

Ok, I know from the book that DMSA does not cross the blood brain

barrier. But I have enough doubt that I wanted to open up a friendly

discussion on the topic.

Andy says DMSA does not cross the barrier because the human barrier

is not as permeable as rats. DMSA does cross the barrier in rats. It

is assumed that since human barriers are not as permeable that DMSA

will not cross in humans. But I'm wondering, is anyone aware of hard

scientific evidence that DMSA does not cross the blood brain

barrier? For example, has an autopsy ever been done on someone who

was taking DMSA to see if it was in the brain?

I remember reading that mercury can disrupt, damage, or somehow

alter the brain barrier. Might it be possible that DMSA will not

normally cross the brain barrier, but that it could in someone who

is mercury damaged? Just food for thought.

I can only say that when I take DMSA it definitely feels like it

gets in the brain. I have no doubt about it, except that my favorite

author says it doesn't.

Depending on the website or source, there are claims DMSA does cross

the barrier and also claims that it doesn't. But the hard evidence

indicating why they believe what they do is missing. I haven't seen

convincing undisputable science either way. Does anyone know of any?

[Guest guest]

Andy has said DMSA does not cross the blood brain barrier to a

clinically significant extent, which is different from saying

that not a single molecule of DMSA makes it across.

Go read the section on DMSA on Moria's website - more in A-M

archives, too. I didn't look very hard, but here are a couple:

http://health.groups.yahoo.com/group/Autism-Mercury/message/84471

http://health.groups.yahoo.com/group/Autism-Mercury/message/111049

--

>

> Ok, I know from the book that DMSA does not cross the blood brain

> barrier. But I have enough doubt that I wanted to open up a friendly

> discussion on the topic.

>

> Andy says DMSA does not cross the barrier because the human barrier

> is not as permeable as rats. DMSA does cross the barrier in rats. It

> is assumed that since human barriers are not as permeable that DMSA

> will not cross in humans. But I'm wondering, is anyone aware of hard

> scientific evidence that DMSA does not cross the blood brain

> barrier? For example, has an autopsy ever been done on someone who

> was taking DMSA to see if it was in the brain?

>

> I remember reading that mercury can disrupt, damage, or somehow

> alter the brain barrier. Might it be possible that DMSA will not

> normally cross the brain barrier, but that it could in someone who

> is mercury damaged? Just food for thought.

>

> I can only say that when I take DMSA it definitely feels like it

> gets in the brain. I have no doubt about it, except that my favorite

> author says it doesn't.

>

> Depending on the website or source, there are claims DMSA does cross

> the barrier and also claims that it doesn't. But the hard evidence

> indicating why they believe what they do is missing. I haven't seen

> convincing undisputable science either way. Does anyone know of any?

>

[Guest guest]

Hi J,

I haven't seen any indisputable scientific evidence that says DMSA does or

does not cross the blood brain barrier. All I can say is that based on my

personal experience, doing five rounds of DMSA has diminished my brain fog

significantly and eradicated my blurry vision. I am doing colonics and far

infared saunas though, too, so I can't say it was the DMSA alone.

~ Carlin

stringworship jlafolle@...> wrote:

Ok, I know from the book that DMSA does not cross the blood brain

barrier. But I have enough doubt that I wanted to open up a friendly

discussion on the topic.

Andy says DMSA does not cross the barrier because the human barrier

is not as permeable as rats. DMSA does cross the barrier in rats. It

is assumed that since human barriers are not as permeable that DMSA

will not cross in humans. But I'm wondering, is anyone aware of hard

scientific evidence that DMSA does not cross the blood brain

barrier? For example, has an autopsy ever been done on someone who

was taking DMSA to see if it was in the brain?

I remember reading that mercury can disrupt, damage, or somehow

alter the brain barrier. Might it be possible that DMSA will not

normally cross the brain barrier, but that it could in someone who

is mercury damaged? Just food for thought.

I can only say that when I take DMSA it definitely feels like it

gets in the brain. I have no doubt about it, except that my favorite

author says it doesn't.

Depending on the website or source, there are claims DMSA does cross

the barrier and also claims that it doesn't. But the hard evidence

indicating why they believe what they do is missing. I haven't seen

convincing undisputable science either way. Does anyone know of any?

---------------------------------

Never miss a thing. Make Yahoo your homepage.

[Guest guest]

Hi J,

I haven't seen any indisputable scientific evidence that says DMSA does or

does not cross the blood brain barrier. All I can say is that based on my

personal experience, doing five rounds of DMSA has diminished my brain fog

significantly and eradicated my blurry vision. I am doing colonics and far

infared saunas though, too, so I can't say it was the DMSA alone.

~ Carlin

stringworship jlafolle@...> wrote:

Ok, I know from the book that DMSA does not cross the blood brain

barrier. But I have enough doubt that I wanted to open up a friendly

discussion on the topic.

Andy says DMSA does not cross the barrier because the human barrier

is not as permeable as rats. DMSA does cross the barrier in rats. It

is assumed that since human barriers are not as permeable that DMSA

will not cross in humans. But I'm wondering, is anyone aware of hard

scientific evidence that DMSA does not cross the blood brain

barrier? For example, has an autopsy ever been done on someone who

was taking DMSA to see if it was in the brain?

I remember reading that mercury can disrupt, damage, or somehow

alter the brain barrier. Might it be possible that DMSA will not

normally cross the brain barrier, but that it could in someone who

is mercury damaged? Just food for thought.

I can only say that when I take DMSA it definitely feels like it

gets in the brain. I have no doubt about it, except that my favorite

author says it doesn't.

Depending on the website or source, there are claims DMSA does cross

the barrier and also claims that it doesn't. But the hard evidence

indicating why they believe what they do is missing. I haven't seen

convincing undisputable science either way. Does anyone know of any?

---------------------------------

Never miss a thing. Make Yahoo your homepage.

[Guest guest]

>

> Ok, I know from the book that DMSA does not cross the blood brain

> barrier. But I have enough doubt that I wanted to open up a friendly

> discussion on the topic.

>

> Andy says DMSA does not cross the barrier because the human barrier

> is not as permeable as rats. DMSA does cross the barrier in rats. It

> is assumed that since human barriers are not as permeable that DMSA

> will not cross in humans. But I'm wondering, is anyone aware of hard

> scientific evidence that DMSA does not cross the blood brain

> barrier?

The references can probably be found in archives. Use www.onibasu.com

to search and see what you can find.

I did go through the papers at one time, but I didn't memorize them.

For example, has an autopsy ever been done on someone who

> was taking DMSA to see if it was in the brain?

>

> I remember reading that mercury can disrupt, damage, or somehow

> alter the brain barrier. Might it be possible that DMSA will not

> normally cross the brain barrier, but that it could in someone who

> is mercury damaged? Just food for thought.

>

> I can only say that when I take DMSA it definitely feels like it

> gets in the brain. I have no doubt about it, except that my favorite

> author says it doesn't.

>

Remember that brain chemicals start out in the body before they get to

the brain. Lots of simple things like sodium, potassium, magnesium,

sugar, water can have huge effects of brain function, so it's not so

difficult to imagine how removing mercury from the body can help or

affect brain function.

My end of round reaction to DMSA was totally a brain reaction - but I

don't think that meant the DMSA got into my brain. I think it was

more like some of the redistributed mercury collided with my adrenals

and caused a stress reaction and electrolyte imbalance.

> Depending on the website or source, there are claims DMSA does cross

> the barrier and also claims that it doesn't. But the hard evidence

> indicating why they believe what they do is missing.

It's not missing. Some papers are 'good', others are misleading, and

some are misinterpreted. I believe that Andy has explained some of

the papers that people refer to and his comments should be in archives

somewhere.

I haven't seen

> convincing undisputable science either way. Does anyone know of any?

>

[Guest guest]

Recently I edited wikipedia articles on DMSA, DMPS and ALA giving

references in peer-reviewed journals stating that DMSA and DMPS don't

chelate mercury from the brain but that ALA does cross the BBB.

You can check the articles and the corresponding references at

http://en.wikipedia.org/wiki/Dimercaptosuccinic_acid

http://en.wikipedia.org/wiki/2%2C3-Dimercapto-1-propanesulfonic_acid

http://en.wikipedia.org/wiki/Lipoic_acid

Best regards,

>

> Ok, I know from the book that DMSA does not cross the blood brain

> barrier. But I have enough doubt that I wanted to open up a friendly

> discussion on the topic.

>

> Andy says DMSA does not cross the barrier because the human barrier

> is not as permeable as rats. DMSA does cross the barrier in rats. It

> is assumed that since human barriers are not as permeable that DMSA

> will not cross in humans. But I'm wondering, is anyone aware of hard

> scientific evidence that DMSA does not cross the blood brain

> barrier? For example, has an autopsy ever been done on someone who

> was taking DMSA to see if it was in the brain?

>

> I remember reading that mercury can disrupt, damage, or somehow

> alter the brain barrier. Might it be possible that DMSA will not

> normally cross the brain barrier, but that it could in someone who

> is mercury damaged? Just food for thought.

>

> I can only say that when I take DMSA it definitely feels like it

> gets in the brain. I have no doubt about it, except that my favorite

> author says it doesn't.

>

> Depending on the website or source, there are claims DMSA does cross

> the barrier and also claims that it doesn't. But the hard evidence

> indicating why they believe what they do is missing. I haven't seen

> convincing undisputable science either way. Does anyone know of any?

>

[Guest guest]

I recently put together a compilation of posts by Andy on the subject

of brain clearance of mercury here:

http://onibasu.com/wiki/Cutler_protocol#Brain_clearance_of_mercury

It includes this analysis of the DMSA study on rats which hasn't been

mentioned yet in this thread. It quantifies his later comments that

DMSA does cross the BBB but not to any useful extent.

http://onibasu.com/archives/am/2411.html

Jay