The role of thiols, dithiols, nutritional factors and interacting ligands in the

[Guest guest]

Hi all,

I was searching for something and came accross this article. It is

interesting that they mention ALA and can be used as a chelator " when

used in an appropriate manner " .

The role of thiols, dithiols, nutritional factors and interacting

ligands in the toxicology of mercury.

http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed&Cmd=ShowDetailView&TermToSearch=17408840

A couple of items of interest that I wonder if an expert can chime in

on.

" Whilst N-acetyl-cysteine (NAC) and glutathione (GSH) have been

recommended in the treatment of mercury toxicity in the past, an

examination of available evidence suggests these agents may in fact

be counterproductive. "

Ok, given that neither of these are a chelator this seems right.

Though I thought that GSH was involved in clearing cells of heavy

metals.

" Evidence suggests however that the co-administration of selenium and

dithiol chelation agents during treatment may also be counter-

productive. "

This last one interested me the most. Any thoughts on this?

Anyone have access to the whole article? I'd like to read it.

Thanks,

Mike