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Re: OT. Science, medical people, anyone, please help.

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, I get this technical explanation of Phentermine from Wikipedia

(http://en.wikipedia.org/wiki/Phentermine). The article is mostly

about the weight-loss use of Phentermine.

Phentermine, like many other prescription drugs, works with

neurotransmitters in the brain. It is a centrally-acting stimulant and

is a constitutional isomer (not to be confused with stereoisomer) of

methamphetamine. It stimulates neuron bundles to release a particular

group of neurotransmitters known as catecholamines; these include

dopamine, epinephrine (also known as adrenaline), and norepinephrine

(noradrenaline). The anorectic activity seen with these compounds is

thus likely due to their effect on the central nervous system, which

is consistent with current knowledge about the central nervous system

and feeding behavior. This is the same mechanism of action as other

stimulant appetite suppressants such as diethylpropion and

phendimetrazine. The neurotransmitters signal a fight-or-flight

response in the body which, in turn, puts a halt to the hunger signal.

As a result, it causes a loss in appetite because the brain does not

receive the hunger message.

The part that sticks out to me is how Phentermine causes the release

of neurotransmitters (dopamine, adrenaline and noradrenaline). I would

suspect this is what makes you feel so good. Only my guess though :)

>

> What is the physiological response to phentermine? I am 69 years

old, physically in pretty good shape, but have been sick for the past

ten years. Retired in 2003 because I was too sick to work, eventually

diagnosed with lead and mercury poisoning in 2006. Fatigue, muscle

weakness, tremors, brain fog. I don't even remember who I was, but if

I take a dose of phentermine, doesn't matter if it's 30 or 37 mg, I am

my old self for the rest of the day.

>

> I only take them twice a week. I am aware that taking them often

would build up a tolerance and I would have to increase the dose, but

this activity is so important to my mental health, I never exceed this

dosage.

>

> What switch is phentermine turning on? A fractured arm wouldn't

work, no matter what pill I took so what system is so damaged that on

one day I can barely get out of bed, but if I take a phentermine I am

restored, temporarily, to feeling great.

>

> Chelated with EDTA IV's for a year, then switched to Andy's

protocol in Jan 2008.

>

> Really looking forward to some explanations. Thank you so much.

>

>

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