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why can dmsa cause neutropenia (low white cell counts)

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Why can dmsa cause low white cell counts? is it something in the dmsa

itself?

is it only dmsa which can cause this?

or does the process of chelatiion cause low white cell counts too?

many thanks jim

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I've been curious about this as well. I hope someone can answer this.

Mike

>

> Why can dmsa cause low white cell counts? is it something in the dmsa

> itself?

> is it only dmsa which can cause this?

> or does the process of chelatiion cause low white cell counts too?

> many thanks jim

>

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Mine were quite low when I was really toxic & first diagnosed.

After on & off DMSA/ALA chelation last year, my WBC's were finally

starting to cross into low normals. I've assumed immune reactivity

& exhaustion and/or weak cellular functions due to HG cause it, but

I also had a lot of malabsorption problems in the past, too.

In any event, I suspect that by stirring up more HG into the

bloodstream through chelation, WBC's can lower. Maybe this is one

of the reasons why people say they feel better on DMPS.

Joanne

> >

> > Why can dmsa cause low white cell counts? is it something in the

dmsa

> > itself?

> > is it only dmsa which can cause this?

> > or does the process of chelatiion cause low white cell counts

too?

> > many thanks jim

> >

>

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Mine were quite low when I was really toxic & first diagnosed.

After on & off DMSA/ALA chelation last year, my WBC's were finally

starting to cross into low normals. I've assumed immune reactivity

& exhaustion and/or weak cellular functions due to HG cause it, but

I also had a lot of malabsorption problems in the past, too.

In any event, I suspect that by stirring up more HG into the

bloodstream through chelation, WBC's can lower. Maybe this is one

of the reasons why people say they feel better on DMPS.

Joanne

> >

> > Why can dmsa cause low white cell counts? is it something in the

dmsa

> > itself?

> > is it only dmsa which can cause this?

> > or does the process of chelatiion cause low white cell counts

too?

> > many thanks jim

> >

>

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Mine were quite low when I was really toxic & first diagnosed.

After on & off DMSA/ALA chelation last year, my WBC's were finally

starting to cross into low normals. I've assumed immune reactivity

& exhaustion and/or weak cellular functions due to HG cause it, but

I also had a lot of malabsorption problems in the past, too.

In any event, I suspect that by stirring up more HG into the

bloodstream through chelation, WBC's can lower. Maybe this is one

of the reasons why people say they feel better on DMPS.

Joanne

> >

> > Why can dmsa cause low white cell counts? is it something in the

dmsa

> > itself?

> > is it only dmsa which can cause this?

> > or does the process of chelatiion cause low white cell counts

too?

> > many thanks jim

> >

>

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thats very interesting joanne that you say you have had low white

cells AND malabsorbtion, because I suffer from both too, do you know

what was causing your malabsorbtion and did you manage to fix it?

many thanks Jim

> > >

> > > Why can dmsa cause low white cell counts? is it something in the

> dmsa

> > > itself?

> > > is it only dmsa which can cause this?

> > > or does the process of chelatiion cause low white cell counts

> too?

> > > many thanks jim

> > >

> >

>

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thats very interesting joanne that you say you have had low white

cells AND malabsorbtion, because I suffer from both too, do you know

what was causing your malabsorbtion and did you manage to fix it?

many thanks Jim

> > >

> > > Why can dmsa cause low white cell counts? is it something in the

> dmsa

> > > itself?

> > > is it only dmsa which can cause this?

> > > or does the process of chelatiion cause low white cell counts

> too?

> > > many thanks jim

> > >

> >

>

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thats very interesting joanne that you say you have had low white

cells AND malabsorbtion, because I suffer from both too, do you know

what was causing your malabsorbtion and did you manage to fix it?

many thanks Jim

> > >

> > > Why can dmsa cause low white cell counts? is it something in the

> dmsa

> > > itself?

> > > is it only dmsa which can cause this?

> > > or does the process of chelatiion cause low white cell counts

> too?

> > > many thanks jim

> > >

> >

>

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>

> Why can dmsa cause low white cell counts? is it something in the dmsa

> itself?

> is it only dmsa which can cause this?

> or does the process of chelatiion cause low white cell counts too?

> many thanks jim

>

To be precise, neutropenia is a low number of neutrophils. This

is different from the overall white blood cell count, which includes

the basophils, monocytes, lymphocytes, and eosinophils, along with

the neutrophils. DMSA can cause a reduction specifically in the

neutrophils, not other white blood cells.

I don't know exactly how DMSA causes neutropenia.

The process of chelation does not inherently reduce neutrophil count

or overall white count.

Some mercury toxic people have reduced neutrophil levels as an effect

of toxicity.

--

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>

> Why can dmsa cause low white cell counts? is it something in the dmsa

> itself?

> is it only dmsa which can cause this?

> or does the process of chelatiion cause low white cell counts too?

> many thanks jim

>

To be precise, neutropenia is a low number of neutrophils. This

is different from the overall white blood cell count, which includes

the basophils, monocytes, lymphocytes, and eosinophils, along with

the neutrophils. DMSA can cause a reduction specifically in the

neutrophils, not other white blood cells.

I don't know exactly how DMSA causes neutropenia.

The process of chelation does not inherently reduce neutrophil count

or overall white count.

Some mercury toxic people have reduced neutrophil levels as an effect

of toxicity.

--

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>

> Why can dmsa cause low white cell counts? is it something in the dmsa

> itself?

> is it only dmsa which can cause this?

> or does the process of chelatiion cause low white cell counts too?

> many thanks jim

>

To be precise, neutropenia is a low number of neutrophils. This

is different from the overall white blood cell count, which includes

the basophils, monocytes, lymphocytes, and eosinophils, along with

the neutrophils. DMSA can cause a reduction specifically in the

neutrophils, not other white blood cells.

I don't know exactly how DMSA causes neutropenia.

The process of chelation does not inherently reduce neutrophil count

or overall white count.

Some mercury toxic people have reduced neutrophil levels as an effect

of toxicity.

--

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Jim, I know the malabsorption was clearing somewhat in the year

leading up to learning about my Hg toxicity.

I was put on an anti-candida diet & detox protocol while my doctor

was trying to deal with many low hormone counts. When I wasn't

responding well in a few months, more testing was showing lots of

mineral deficiencies, extensive allergies/sensitivities, and

multiple infections of every sort. It was very strange that while

bacterial & viral infections, and even a single-celled amoeba called

dientamoeba fragillis was running rampant, (and candida wasn't being

given a chance!), my immune system wasn't reacting by increasing the

appropriate WBC's in any of the appropriate forms (neutrophils,

eosinophils, basophils, etc.). They were borderline or below normal.

Through about a year of trial & error & testing, signs of infection

would go up and down. Gradually, chronic fatigue 'bad flu' -type

symptoms were gone, my digestion improved on a very rigid diet, I

started putting on a few pounds again, and cholesterol levels came

up.

Stool sample testing through Geneva Labs (then Great Smokies) was

helpful & ID'd the parasite, which had resisted prior parasite

cleanses which were done just to eliminate the parasite possibility.

We found I was Hg toxic at this point because so many other symptoms

weren't improving, in my case dementia, fatigue, & those associated

with low hormone levels being the worst. No matter what I've done

or how strict the diet, I have to supplement for my immune function,

minerals, etc., or I slip back and get infections. It's been 5

years now since getting malabsorption under control. My own belief

is that years and years of an unchecked mercury-filled, root-canaled

absess set me up with at least one bacterial superbug that found its

home in my digestive tract & did plenty of damage. But I'm always

told I had a lot of oxidative damage, too, so I suspect that

involves cellular damage in the digestive tract as well as other

places. I had mixed metals and a mouth full of amalgam for 30

years, plus new amalgams every year throughout childhood. I chewed

a LOT of gum to deal with the metal taste.

Other than correct vitamin/mineral supplements & lots of C, I think

the Omega 3 & 6 oils are pretty important for correcting

malabsorption. Correcting my pH is a big deal, too. If I allow

myself to get away from foods that keep me from being too acidic,

I'm definitely in trouble. Avoiding sensitive/allergic foods &

herbal supplements is critical to stop inflammation & allow healing

to occur -- I had to get those identified. Any infections you can

get positively identified via stool sample testing can be of great

help. In my case, preventing constipation is very important, too,

and I take a magnesium peroxide product recommended by a colon

therapist called " Oxycleanse " from Earth's Bounty for that. I doubt

I make adequate hormones in the digestive tract on my own to

maintain good function otherwise.

There's lots of things that can contribute to malabsorption, I'm

sure, but the granddaddy for me had to be a steady stream of

mercury. No doubt excess candida did some permanent damage in the

years it had a chance, and the continuous inflammation from exposure

to food allergens like onions, dairy, wheat & yeast did the job as

well.

I guess what I can tell you is that I've learned how to manage

malabsorption & poor immune function. I haven't succeeded in being

able to live a typical life at all, and that's why I'm chelating.

Joanne

> >

> > Mine were quite low when I was really toxic & first diagnosed.

> > After on & off DMSA/ALA chelation last year, my WBC's were

finally

> > starting to cross into low normals. I've assumed immune

reactivity

> > & exhaustion and/or weak cellular functions due to HG cause it,

but

> > I also had a lot of malabsorption problems in the past, too.

> >

> > In any event, I suspect that by stirring up more HG into the

> > bloodstream through chelation, WBC's can lower. Maybe this is

one

> > of the reasons why people say they feel better on DMPS.

> >

> > Joanne

> >

> >

> >

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am i right in thinking that IF for any reason dmsa did cause

neutropenia would stopping the dmsa allow the white cells to recover

back to normal or is neutropenia a permanent thing????

thanks

> >

> > Why can dmsa cause low white cell counts? is it something in the dmsa

> > itself?

> > is it only dmsa which can cause this?

> > or does the process of chelatiion cause low white cell counts too?

> > many thanks jim

> >

>

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Share on other sites

>

> am i right in thinking that IF for any reason dmsa did cause

> neutropenia would stopping the dmsa allow the white cells to recover

> back to normal or is neutropenia a permanent thing????

It is most likely that it is excessive doses of DMSA could lead to

neutropenia and mostly in individuals who are already susceptible

because of their genetics or the extent of their toxicity.

Using DMSA in the low doses we use with Andy's protocol is not likely

to lead to neutropenia (compare the dose range he uses of 1/8 - 1/2 mg

per pound to the doses other doctors commonly prescribe - up to 10 mg/kg).

Neutropenia can be reversed. I have seen examples of this on autism

mercury.

Neutropenia is low neutrophils.

J

> thanks

>

>

>

>

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