Re: Shizume study on long term ATDs

[Guest guest]

You are amazing! Great find.

Terry

>

> Reply-To: graves_support

> Date: Mon, 02 Dec 2002 22:00:59 -0000

> To: graves_support

> Subject: Shizume study on long term ATDs

>

> Hi all -

>

> I see that in the mid 20th century in Japan, it was generally

> accepted that ATDs could be taken long term with no ill side effects:

>

> QUOTE:

>

> K Shizume

> Long term antithyroid drug therapy for intractable cases of Graves'

> disease.

> Endocrinol Jpn, August 1, 1978; 25(4): 377-9.

>

> Among the 504 patients with Graves' disease in whom the author

> initiated antithyroid drug therapy between 1956 and 1968 are 14 to

> whom the administration of antithyroid drug has been continued for 8

> to 21 years because of recurrence shortly after the discontinuation

> of drugs. During these periods, no side effects were observed and

> three patients went into complete remission after 8, 9 and 20 years

> of antithyroid drug administration, respectively. It is suggested

> therefore that the long term administration of antithryoid drugs can

> be a useful treatment for intractable cases.

>

> END QUOTE.

>

> (Intractible means " not easily managed or controlled " so I gather the

> other study participants went into remission...?)

>

> Now the big question: Why was it acceptable then, but American endos

> push destruction of the thyroid gland and insist that ATDs are too

> toxic to bother with??

>

> Inquiring minds want to know. Copy this and take it to your next

> endo visit. I'd post the link, but once again it is too long to copy

> correctly.

>

> Best Wishes,

> Chris

>

>

>

>

>

> -------------------------------------

> The Graves' list is intended for informational purposes only and is not

> intended to replace expert medical care.

> Please consult your doctor before changing or trying new treatments.

> ----------------------------------------

> DISCLAIMER

>

> Advertisments placed on this yahoo groups list do not have the endorsement of

> the listowner. I have no input as to what ads are attached to emails.

> ------------------------------------------------------------------------------

> --------

>

>

[Guest guest]

You are amazing! Great find.

Terry

>

> Reply-To: graves_support

> Date: Mon, 02 Dec 2002 22:00:59 -0000

> To: graves_support

> Subject: Shizume study on long term ATDs

>

> Hi all -

>

> I see that in the mid 20th century in Japan, it was generally

> accepted that ATDs could be taken long term with no ill side effects:

>

> QUOTE:

>

> K Shizume

> Long term antithyroid drug therapy for intractable cases of Graves'

> disease.

> Endocrinol Jpn, August 1, 1978; 25(4): 377-9.

>

> Among the 504 patients with Graves' disease in whom the author

> initiated antithyroid drug therapy between 1956 and 1968 are 14 to

> whom the administration of antithyroid drug has been continued for 8

> to 21 years because of recurrence shortly after the discontinuation

> of drugs. During these periods, no side effects were observed and

> three patients went into complete remission after 8, 9 and 20 years

> of antithyroid drug administration, respectively. It is suggested

> therefore that the long term administration of antithryoid drugs can

> be a useful treatment for intractable cases.

>

> END QUOTE.

>

> (Intractible means " not easily managed or controlled " so I gather the

> other study participants went into remission...?)

>

> Now the big question: Why was it acceptable then, but American endos

> push destruction of the thyroid gland and insist that ATDs are too

> toxic to bother with??

>

> Inquiring minds want to know. Copy this and take it to your next

> endo visit. I'd post the link, but once again it is too long to copy

> correctly.

>

> Best Wishes,

> Chris

>

>

>

>

>

> -------------------------------------

> The Graves' list is intended for informational purposes only and is not

> intended to replace expert medical care.

> Please consult your doctor before changing or trying new treatments.

> ----------------------------------------

> DISCLAIMER

>

> Advertisments placed on this yahoo groups list do not have the endorsement of

> the listowner. I have no input as to what ads are attached to emails.

> ------------------------------------------------------------------------------

> --------

>

>

[Guest guest]

Hi Terry -

Actually Jody recently built a fire under me to start researching

ATDs and I stumbled upon this. To be perfectly honest, several years

ago U. told me about this Japanese study, but it took me this

long to find the darn thing!

Best Wishes,

Chris

>

>

> You are amazing! Great find.

>

> Terry

>

>