3 hourly schedule for DMSA? & Re: Question about DMSA dosage

[Guest guest]

In frequent-dose-chelation toowittybird wrote:

> Posted by: " toowittybird " toowittybird@...

>

> Fri Mar 7, 2008 8:44 am (PST)

>

> >Can DMSA be administered every 3 hours during the day and 4 hours

> >during the night? Should it still total 18 doses in total or

should it

> >be given for a total of 72 hours implying that it would be

more than

> >18 doses in the latter case?

>

> If you are doing 3 hours at night and 4 in the day, there will be

> more than 18 doses in 3 days - otherwise you would have more than a

> 4 hour break in the day.

Well, that is my question- are we supposed to do 72 hours in total

whether the number of doses comes out to 18 or whether the number

comes out to more than 18?

-----------The number of doses you take in 72 hours, whether it is 18 or 19 or

20, doesn't really matter. What does matter is that you chelate continuously

for about 72 hours, or 3 days. Some people dose every 4 hours, some dose every

3 hours for DMSA. When people take ALA, some dose even more often than every 3

hours, maybe every 2. When people take DMPS, some dose at 8 hours and some do

every 6 hours. So the number of doses during a round can be different, even

with the same chelator.

So what *is* important is that you take the chelator based on its half life,

continuously, for 3 days. A few hours more or a few hours less is ok too. And

the number of doses taken during that time isn't important, as long as the blood

levels of the chelators are kept fairly stable by dosing frequently

enough.-------Jackie

[Guest guest]

In frequent-dose-chelation toowittybird wrote:

> Posted by: " toowittybird " toowittybird@...

>

> Fri Mar 7, 2008 8:44 am (PST)

>

> >Can DMSA be administered every 3 hours during the day and 4 hours

> >during the night? Should it still total 18 doses in total or

should it

> >be given for a total of 72 hours implying that it would be

more than

> >18 doses in the latter case?

>

> If you are doing 3 hours at night and 4 in the day, there will be

> more than 18 doses in 3 days - otherwise you would have more than a

> 4 hour break in the day.

Well, that is my question- are we supposed to do 72 hours in total

whether the number of doses comes out to 18 or whether the number

comes out to more than 18?

-----------The number of doses you take in 72 hours, whether it is 18 or 19 or

20, doesn't really matter. What does matter is that you chelate continuously

for about 72 hours, or 3 days. Some people dose every 4 hours, some dose every

3 hours for DMSA. When people take ALA, some dose even more often than every 3

hours, maybe every 2. When people take DMPS, some dose at 8 hours and some do

every 6 hours. So the number of doses during a round can be different, even

with the same chelator.

So what *is* important is that you take the chelator based on its half life,

continuously, for 3 days. A few hours more or a few hours less is ok too. And

the number of doses taken during that time isn't important, as long as the blood

levels of the chelators are kept fairly stable by dosing frequently

enough.-------Jackie

[Guest guest]

>

> > Posted by: " toowittybird " toowittybird@

> >

> > Fri Mar 7, 2008 8:44 am (PST)

> >

> > >Can DMSA be administered every 3 hours during the day and 4 hours

> > >during the night? Should it still total 18 doses in total or

> should it

> > >be given for a total of 72 hours implying that it would be

> more than

> > >18 doses in the latter case?

>

> >

> > If you are doing 3 hours at night and 4 in the day, there will be

> > more than 18 doses in 3 days - otherwise you would have more than a

> > 4 hour break in the day.

>

> Well, that is my question- are we supposed to do 72 hours in total

> whether the number of doses comes out to 18 or whether the number

> comes out to more than 18?

>

> -----------The number of doses you take in 72 hours, whether it is

18 or 19 or 20, doesn't really matter. What does matter is that you

chelate continuously for about 72 hours, or 3 days. Some people dose

every 4 hours, some dose every 3 hours for DMSA. When people take

ALA, some dose even more often than every 3 hours, maybe every 2.

When people take DMPS, some dose at 8 hours and some do every 6 hours.

So the number of doses during a round can be different, even with the

same chelator.

>

> So what *is* important is that you take the chelator based on its

half life, continuously, for 3 days. A few hours more or a few hours

less is ok too. And the number of doses taken during that time isn't

important, as long as the blood levels of the chelators are kept

fairly stable by dosing frequently enough.-------Jackie

>

>

>

>

>

>

>

>

>

>

[Guest guest]

Posted by: " toowittybird " toowittybird@...

toowittybird@...?Subject=%20Re%3A3%20hourly%20schedule%20for%20DMS\

A%3F%20%26%20Re%3A%20%20Question%20about%20DMSA%20dosage>

toowittybird http://profiles.yahoo.com/toowittybird>

Fri Mar 7, 2008 3:50 pm (PST)

>> If you are doing 3 hours at night and 4 in the day, there will be

>> more than 18 doses in 3 days - otherwise you would have more than a

>> 4 hour break in the day.

>Well, that is my question- are we supposed to do 72 hours in total

>whether the number of doses comes out to 18 or whether the number

>comes out to more than 18?

Ya, 72 hours total - at least. The point is basically to try to avoid

having the side effects that you get at the start of the round from

overlapping with the side effects that you get at the end.

Dave.