Guest guest Posted February 1, 2008 Report Share Posted February 1, 2008 The difference in what is absorbed with food or without food won't be large enough to make a large enough difference to blood levels to make a difference to chelation. With taking ALA every 3 h in the day, 4 h at night, it would be difficult, maybe close to impossible, to always take on an empty stomach. People with adrenal problems need to eat frequently. J > > I'm about to start chelating with ALA, after several rounds of DMSA > alone. > > I've found in several places (see links below) that the > bioavailability of ALA is reduced if taken too close to meals, so the > recommendation is to take ALA on an empty stomach. This seems > especially important for chelation, if one aims to keep blood levels > of ALA relatively constant throughout the round. > > http://www.doctormurray.com/ask/alphalipoic.asp > http://www.pdrhealth.com/drugs/altmed/altmed-mono.aspx?contentFileName=ame0292.x\ ml&contentName=Alpha+Lipoic+Acid&contentId=452 > http://www.integranutrition.com/lipoic-acid-sheet.html > > However, I've seen suggestions on this site (and on Adult Toxic Metals > Chelation) that it doesn't matter whether one takes ALA with or apart > from food. If that is true, how do we know? Is it based on > experience -- that taking w/ or without food doesn't seem to matter > for many individuals? Or some Russian journal article? :-) > > Or perhaps the bioavailability of ALA with vs. apart from food is > different, but the difference is simply too small to have an impact. > > Clearly, avoiding food when taking ALA every three hours is a > challenging endeavor. It would certainly be more convenient if one > didn't have to worry about this issue. Maybe the easiest thing to do, > if one is concerned about consistency of blood levels of ALA, is to > take ALA with food every time, reducing bioavailability slightly but > increasing consistency (?). But would it have to be roughly the same > amount of food? (I'm not planning on consuming any full meals at > 3am... ;-) ) > > Same issue for DMSA. The standard (old/outdated?) protocol is to take > DMSA apart from food. However, recommendations on this site include > sprinkling DMSA on applesauce, e.g., to help it go down easier for kids. > > Maybe this is really a non-issue and is just a reflection on my > perfectionist tendency. But each previous post about the " with or > without food " issue has including some uncertainty, such as " I think, " > or " I believe " . So I figured I'd bring it up again to see if it's > possible to resolve the matter. Andy? Anyone? Bueller? > > Thanks! > Darren > Quote Link to comment Share on other sites More sharing options...
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