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Re: Re: OT--SH groups in collagen and fat tissues?--Andy

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Thanks Andy for responding, and one more question down below. And since I got

your attention, what do you think of the Melisa Test for metal allergy? Have

you had the opportunity to see many people who have done both, the Melisa Test

and a hair test? I'm curious if they follow suit, or do some people have low

body burdens and don't meet the counting rules, but have a high reactivity to

mercury on the Melisa test? Would their symptoms be any different? If someone

didn't meet the counting rules, but still suspected mercury, would this be a

reasonable test to do? Would those of us who do meet the counting rules, would

we show reactivity to mercury on a Melisa Test? Or is this two separate things,

allergy/reactivity and toxicity/body burden? (Sorry so many questions, I like

to pick your brain when I get a chance!) Thanks-----Jackie

In frequent-dose-chelation andrewhallcutler wrote:

>

>

> >

> > Ok, you chemistry people, I knew mercury was attracted to SH groups,

> and that's what makes the chelators work (double thiols), but I did

> not realize that fat and collagen tissues were rich in SH groups.

They are not rich in thiol groups, compared to the rest of the body they are

actually quite

poor in thiol groups.

-----------So we can all learn something, which parts of the body are highest

in thiol (SH) groups? (I assume the brain is one? Organs and glands?) So

mercury wouldn't be very likely to accumulate in fat tissue or collagen? But

the brain is high in fat, and mercury accumulates there, so is it because of its

fat content, having thiols, or what?---------Jackie

> > http://www.melisa.org/mercury.php

> >

> > (quote is from the paragraph right above the pictures)

> >

> > " The pictures demonstrate widespread distribution of mercury in the

> body of the mice. Organs rich in fat - such as brain and collagen

As in all too much of medicine, ignorance doesn't prevent them from holding

forth.

The brain is high in fat. Collagen is very low in fat (like almost zero).

> are very prone to mercury binding. One of the reasons for this is that

> mercury is particularly keen to bind to two amino acids; methionine

> and cysteine. Both amino acids contain sulphur hydrogen (SH)-groups.

Methionine does not contain a sulfhydryl (thiol, SH) group.

This is the boon and the bane of the internet. Every idiot can make a web page

and most

do. Because of this the usual forces of political correctness do not edit out

politically

incorrect information so you can find that tidbit of truth you need, but you

have to wade

through a LOT of misinformation to find it.

Andy

._,_.___

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