Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. Dave --- Jackie jtrunt@...> wrote: > This isn't the recent post you were looking for, but > this is one of them from the ANDY INDEX in the FILES > section, that addresses this. > http://health.groups.yahoo.com/group/Autism-Mercury/message/36193 > > If you haven't been there yet, there is tons of > posts by Andy to read in the ANDY INDEX. Just click > on Visit Your Group on the right side of the page, > then click on FILES and then ANDY INDEX. > > Jackie > > > > In frequent-dose-chelation > sunshinep1969 wrote: > > Sorry, i'm looking for the post that discuss's > taking higher doses of > dmsa and ala only increases the effectiveness by > about, was it 30pct? > but massively increases the side effects. > > Can someone remind me of the link 'cause i can't > find it. it was > within the last week or two. > > Cheers, Sunshine > > > > > > [Non-text portions of this message have been > removed] > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. Dave --- Jackie jtrunt@...> wrote: > This isn't the recent post you were looking for, but > this is one of them from the ANDY INDEX in the FILES > section, that addresses this. > http://health.groups.yahoo.com/group/Autism-Mercury/message/36193 > > If you haven't been there yet, there is tons of > posts by Andy to read in the ANDY INDEX. Just click > on Visit Your Group on the right side of the page, > then click on FILES and then ANDY INDEX. > > Jackie > > > > In frequent-dose-chelation > sunshinep1969 wrote: > > Sorry, i'm looking for the post that discuss's > taking higher doses of > dmsa and ala only increases the effectiveness by > about, was it 30pct? > but massively increases the side effects. > > Can someone remind me of the link 'cause i can't > find it. it was > within the last week or two. > > Cheers, Sunshine > > > > > > [Non-text portions of this message have been > removed] > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 28, 2007 Report Share Posted November 28, 2007 If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. Dave --- Jackie jtrunt@...> wrote: > This isn't the recent post you were looking for, but > this is one of them from the ANDY INDEX in the FILES > section, that addresses this. > http://health.groups.yahoo.com/group/Autism-Mercury/message/36193 > > If you haven't been there yet, there is tons of > posts by Andy to read in the ANDY INDEX. Just click > on Visit Your Group on the right side of the page, > then click on FILES and then ANDY INDEX. > > Jackie > > > > In frequent-dose-chelation > sunshinep1969 wrote: > > Sorry, i'm looking for the post that discuss's > taking higher doses of > dmsa and ala only increases the effectiveness by > about, was it 30pct? > but massively increases the side effects. > > Can someone remind me of the link 'cause i can't > find it. it was > within the last week or two. > > Cheers, Sunshine > > > > > > [Non-text portions of this message have been > removed] > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 What I remember Andy saying is to hold the chelator dose constant for a couple of months once the right dose is found and then increase in small increments to find the next right dose to use for the next several months. It took me over a year at 18 mg DMPS before I could increase to 25 mg DMPS, and now 25 mg feels like plenty. J > > > > Sorry, i'm looking for the post that discuss's > > taking higher doses of > > dmsa and ala only increases the effectiveness by > > about, was it 30pct? > > but massively increases the side effects. > > > > Can someone remind me of the link 'cause i can't > > find it. it was > > within the last week or two. > > > > Cheers, Sunshine > > > > > > > > > > > > [Non-text portions of this message have been > > removed] > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 What I remember Andy saying is to hold the chelator dose constant for a couple of months once the right dose is found and then increase in small increments to find the next right dose to use for the next several months. It took me over a year at 18 mg DMPS before I could increase to 25 mg DMPS, and now 25 mg feels like plenty. J > > > > Sorry, i'm looking for the post that discuss's > > taking higher doses of > > dmsa and ala only increases the effectiveness by > > about, was it 30pct? > > but massively increases the side effects. > > > > Can someone remind me of the link 'cause i can't > > find it. it was > > within the last week or two. > > > > Cheers, Sunshine > > > > > > > > > > > > [Non-text portions of this message have been > > removed] > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 What I remember Andy saying is to hold the chelator dose constant for a couple of months once the right dose is found and then increase in small increments to find the next right dose to use for the next several months. It took me over a year at 18 mg DMPS before I could increase to 25 mg DMPS, and now 25 mg feels like plenty. J > > > > Sorry, i'm looking for the post that discuss's > > taking higher doses of > > dmsa and ala only increases the effectiveness by > > about, was it 30pct? > > but massively increases the side effects. > > > > Can someone remind me of the link 'cause i can't > > find it. it was > > within the last week or two. > > > > Cheers, Sunshine > > > > > > > > > > > > [Non-text portions of this message have been > > removed] > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 In frequent-dose-chelation Sherratt wrote: If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. -------Andy has also said it another way, that excretion increases by about the square root, so taking 4X as much chelator will only increase excretion by about 2X. But symptoms increase linearly, so you would have 4X more/worse symptoms, but only double the excretion, so he doesn't feel it is worth it.---------Jackie I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. -----------This sounds perfect, finding a dose that you feel good at is great. Way better to feel good and be functional and to look forward to your next round, than to push it and feel terrible and not want to do it.----------Jackie I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. ---------We are all different as far as how much chelator we tolerate and how fast we can increase dosages. Some are more toxic than others and/or may have more than one metal to contend with (like I have arsenic also). I was at 12.5mg of DMSA for many months before I could increase to 16mg, and many months there before I finally tolerated 25mg. I am now trying DMPS, only tolerating 15mg of that, and recently tried adding in 6mg of ALA, and it knocked me out. So I am 2+ years post amalgam removal, and still don't tolerate ALA. (I have had alot of family stress and other medical problems during this time, so I haven't chelated steadily this whole time either.) So I prefer finding a dose that I can tolerate and makes me feel better, so I look forward to chelation. I don't want to make myself miserable, just because other people are using higher doses than me, and I think I should too.-----Jackie I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. ---------Raising from 6 to 8mg sounds very reasonable, but I would warn against trying to keep increasing too fast. I would hate to see you screw up the good thing you have going for yourself, feeling great!--------Jackie But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. -----------I totally agree. I don't know why anyone would want to make themselves feel terrible, when they don't have to. And I think you'd be much more likely to stick with it in the long haul and complete chelation, if you stick with doses that make you feel good. I know we can all get ansy and want to get this over with, but like it has been said before, slow and steady wins this race. Good luck, and keep us posted when you do try *small* increases.----------Jackie Dave Recent Activity a.. 10New Members b.. 3New Links Visit Your Group FruitaBü Group A Parent´s Place to share ideas on family cooking. Yahoo! Health Looking for Love? Find relationship advice and answers. Dog Groups on Yahoo! Groups Share pictures & stories about dogs. . Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 In frequent-dose-chelation Sherratt wrote: If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. -------Andy has also said it another way, that excretion increases by about the square root, so taking 4X as much chelator will only increase excretion by about 2X. But symptoms increase linearly, so you would have 4X more/worse symptoms, but only double the excretion, so he doesn't feel it is worth it.---------Jackie I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. -----------This sounds perfect, finding a dose that you feel good at is great. Way better to feel good and be functional and to look forward to your next round, than to push it and feel terrible and not want to do it.----------Jackie I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. ---------We are all different as far as how much chelator we tolerate and how fast we can increase dosages. Some are more toxic than others and/or may have more than one metal to contend with (like I have arsenic also). I was at 12.5mg of DMSA for many months before I could increase to 16mg, and many months there before I finally tolerated 25mg. I am now trying DMPS, only tolerating 15mg of that, and recently tried adding in 6mg of ALA, and it knocked me out. So I am 2+ years post amalgam removal, and still don't tolerate ALA. (I have had alot of family stress and other medical problems during this time, so I haven't chelated steadily this whole time either.) So I prefer finding a dose that I can tolerate and makes me feel better, so I look forward to chelation. I don't want to make myself miserable, just because other people are using higher doses than me, and I think I should too.-----Jackie I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. ---------Raising from 6 to 8mg sounds very reasonable, but I would warn against trying to keep increasing too fast. I would hate to see you screw up the good thing you have going for yourself, feeling great!--------Jackie But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. -----------I totally agree. I don't know why anyone would want to make themselves feel terrible, when they don't have to. And I think you'd be much more likely to stick with it in the long haul and complete chelation, if you stick with doses that make you feel good. I know we can all get ansy and want to get this over with, but like it has been said before, slow and steady wins this race. Good luck, and keep us posted when you do try *small* increases.----------Jackie Dave Recent Activity a.. 10New Members b.. 3New Links Visit Your Group FruitaBü Group A Parent´s Place to share ideas on family cooking. Yahoo! Health Looking for Love? Find relationship advice and answers. Dog Groups on Yahoo! Groups Share pictures & stories about dogs. . Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 In frequent-dose-chelation Sherratt wrote: If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. -------Andy has also said it another way, that excretion increases by about the square root, so taking 4X as much chelator will only increase excretion by about 2X. But symptoms increase linearly, so you would have 4X more/worse symptoms, but only double the excretion, so he doesn't feel it is worth it.---------Jackie I have been taking 6mg because I was scared of allergic reactions. I have been feeling incredibly good during and immediately after rounds, up until about 3 days after I end a round, at which point I start to " feel the mercury " again. This is no worry because I can start a new round. -----------This sounds perfect, finding a dose that you feel good at is great. Way better to feel good and be functional and to look forward to your next round, than to push it and feel terrible and not want to do it.----------Jackie I'm really wondering whether it is ideal to try to raise the amount of chelator to 25mg, or whether this is really more than is necessary (just as the 100mg in Cutler's book turned out to be way high), in addition to causing side effects. ---------We are all different as far as how much chelator we tolerate and how fast we can increase dosages. Some are more toxic than others and/or may have more than one metal to contend with (like I have arsenic also). I was at 12.5mg of DMSA for many months before I could increase to 16mg, and many months there before I finally tolerated 25mg. I am now trying DMPS, only tolerating 15mg of that, and recently tried adding in 6mg of ALA, and it knocked me out. So I am 2+ years post amalgam removal, and still don't tolerate ALA. (I have had alot of family stress and other medical problems during this time, so I haven't chelated steadily this whole time either.) So I prefer finding a dose that I can tolerate and makes me feel better, so I look forward to chelation. I don't want to make myself miserable, just because other people are using higher doses than me, and I think I should too.-----Jackie I'm going to raise my dose to 8mg next round and then continue boosting it every couple rounds after that. ---------Raising from 6 to 8mg sounds very reasonable, but I would warn against trying to keep increasing too fast. I would hate to see you screw up the good thing you have going for yourself, feeling great!--------Jackie But if the alternative is feeling great for 2 years at 6mg or feeling crummy for 14 months at 25mg, I would probably take the former. -----------I totally agree. I don't know why anyone would want to make themselves feel terrible, when they don't have to. And I think you'd be much more likely to stick with it in the long haul and complete chelation, if you stick with doses that make you feel good. I know we can all get ansy and want to get this over with, but like it has been said before, slow and steady wins this race. Good luck, and keep us posted when you do try *small* increases.----------Jackie Dave Recent Activity a.. 10New Members b.. 3New Links Visit Your Group FruitaBü Group A Parent´s Place to share ideas on family cooking. Yahoo! Health Looking for Love? Find relationship advice and answers. Dog Groups on Yahoo! Groups Share pictures & stories about dogs. . Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 29, 2007 Report Share Posted November 29, 2007 Actually, Andy has said that metals removal increases A LITTLE LESS THAN the square root of the increased dose. So it really makes no sense to go up to a dose of chelator that produces a lot of side effects. Low and slow seems to work best. Dean In frequent-dose-chelation Sherratt wrote: If this figure that doubling the dose gets you 30% more chelation is correct, that would mean that 25mg only increases the amount of metals chelated by 70% relative to 6mg. -------Andy has also said it another way, that excretion increases by about the square root, so taking 4X as much chelator will only increase excretion by about 2X. But symptoms increase linearly, so you would have 4X more/worse symptoms, but only double the excretion, so he doesn't feel it is worth it.---------Jackie Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.