Chlorella: A Natural Wonder Food

August 10, 2005

Comparison of Chlorella to Other Green Foods

There are 3 algae and 2 cereal grasses that are commonly available in

the marketplace. The algae are chlorella, spirulina and green blue

algae (aphanizomenon flas-aquae). The grasses are wheat grass and

barley grass.

While all five products are excellent sources of nutrients, chlorella

has properties that make it the most valuable of all the green food

supplements. Chlorella has 5 to 10 times the chlorophyll content of

spirulina, wheat grass and barley grass. It is also higher in

chlorophyll than blue green algae. As a matter of fact, chlorella

contains the highest chlorophyll content of any known plant. Besides

the abundance of chlorophyll, chlorella's tough cell wall offers

advantages not found in other algae or grasses. Chlorella's cell wall

has been shown to eliminate toxins, pesticides, and heavy metals from

the body. Plus the cell wall has the ability to induce interferon

production in the body which is important to immune function.

Chlorella and the other algae are abundant in beta-carotene, which is

known to prevent cancer. The protein content of the algae is

significantly higher than in the cereal grasses. Chlorella is about

60%, spirulina 73%, blue green algae 56%, barley grass 14% and wheat

grass 18%. Chlorella's nucleus is the factor that truly sets it apart

from the other green food supplements though. The nucleus contains

chlorella growth factor. Scientific experiments have indicated that

CGF has great rejuvenating effects. It is extremely rich in the

nucleic acids, RNA and DNA. Laboratory mice fed chlorella have

obtained life span increases of over 30%. Many researchers feel the

CGF is responsible for this increase.

Chlorella is the most researched algae in the world. Spirulina has had

less research, but also shows great promise with its unique

nutritional benefits. There has not been a large amount of research on

blue green algae but many people report positive health benefits.

Chlorella is the world's most popular algae with millions of satisfied

users. It is the most common supplement taken in Japan. It is

frequently added to tea, soup, milk, juice, noodles, yogurt and other

foods.

DOSING OF CHLORELLA

What is the Best Brand and Form of Chlorella?

The chlorella I highly recommended that is known worldwide for its

high quality and absolute purity is Biotics, discussed in more detail

at www.Mercola.com/forms/chlorella.htm.

How Much Should You Take Per Day?

Three grams per day is a good maintenance dosage of Chlorella for a

person to take. With this amount, you will not notice significant

changes, however, your body will get many of the nutrients it must

have to function properly such amino acids (protein), vital minerals,

vitamins, carbohydrates and enzymes.

However, a person taking 5-7 grams per day is quite common and at this

level you will notice significant changes in digestion, energy and

overall health.

If you choose to take about 3 grams per day, each capsule in the 180

capsule container of the brand I highly recommend contains 450 mg, so

that means you should take between 6-7 capsules per day.

What Results Should You Expect When You Begin Taking Chlorella?

The first thing is better digestion, especially if you have bad breath

or constipation. Both these are readily handled by taking small doses

of Chlorella. However, many of the benefits of Chlorella are subtle

and not easily determined by how a person feels.

For instance, Chlorella has been demonstrated to remove heavy metals

and other synthetics from the body by actually binding with them so

they may be pulled from the bloodstream. However, this result can only

be measured if the level of heavy metals in the bloodstream are known

before and after a person starts taking chlorella.

It takes approximately 3-6 months once starting chloreela for heavy

metals to begin to be removed from the blood depending on the amount

of chlorella taken. If it has been determined that a person does have

heavy metals in their body, they should begin by taking 15-20 grams

per day depending on the level of heavy metals that are present.

What Time Of Day Or Night Should You Take It?

Chlorella can be taken at any time of the day. It can be taken all at

once or it can be taken in small dosages throughout the day, which is

preferable. Morning is also a good time to take chlorella, but never

just before or after drinking coffee or soft drinks since caffeine is

extremely detrimental to the digestive process. (We generally advise

people to avoid caffeine anyway).

Chlorella causes the bacteria in our stomachs, the Lactobacilli, to

multiply at 4 times the rate of normal. This is why it is best to take

with meals as chlorella helps provide very good digestion and more

importantly, better assimilation of nutrients.

Can Everyone Tolerate Chlorella?

Because of the fiber content in chlorella's cell wall and other

nutritional factors, when some people begin to take chlorella for the

first time they may go through cleansing reactions, sometimes referred

to as a " healing crisis " . This cleansing reaction comes in the form of

intestinal activity such as gas, cramping, constipation or diarrhea.

This same type of cleansing reaction frequently occurs when people

switch from a low-fiber, " junk-food " diet to a high fiber, natural

food diet. For this reason, some individuals may wish to start out

with less than the suggested amount and gradually increase up to the

recommended dose in 1-2 weeks. Very sensitive individuals may want to

start with as little as a single capsule per day.

If you have not been eating many fresh raw vegetables in your diet, it

is probably a good idea to start out with a single capsule with each

meal and increase by a capsule every 2-3 days. Rarely cleansing

reactions will go on for up to 3 months where one can not increase the

dose beyond a capsule per day.

As long as you are not showing an allergic reaction (such as hives) or

throwing up, you can safely continue the chlorella. In a couple of

months, the reaction should decrease. And as it decreases, you can

increase the dose.

Can You Take Too Much Chlorella?

It is best to think of chlorella as a food because that is exactly

what it is: one of the purest, most potent foods on earth. A person

can not take too much chlorella because it is naturally detoxifying.

Therefore, the fear of chlorella accumulating and becoming toxic to

the body is not present.

However, there is a " comfort level " with every person where he or she

knows how much Chlorella to take per day. In general, that level will

be about 5-8 grams per day.

A person taking 15-20 grams of chlorella per day is not at all unheard

of if someone is trying to combat a disease with the amazing medicinal

properties of chlorella. It is a whole food, not a concentrate or

extract, therefore you can NOT take too much of it because of its

detoxifying abilities.

Are There Conditions Where You Should Take Larger Doses of Chlorella?

Many people with chronic viral conditions, such as Epstein-Barr virus

or Herpes virus have shown significant improvements in their condition

with larger amounts of chlorella. Frequently, these individuals will

need 10 to 15 grams per day (two to three teaspoons).

Should a person keep taking vitamins once they start taking Chlorella?

It would not hurt to keep taking multivitamins with chlorella, but, in

my opinion multivitamins are not needed. Chlorella and a proper diet

contain a wide array of vital vitamins, minerals and nutrients and are

also much more economical than most vitamins.

Can Chlorella Be Used Topically?

Yes. Chlorella can be powdered and mixed with water into a paste and

applied over a cut, scrap, rash or serious wound to help effectively

heal it. It is the Chlorella Growth Factor in the chlorella that makes

it such an effective healer of human tissue. After consuming chlorella

for approximately one year (at levels of 5-7 grams per day), a person

will notice significant healing improvement of cuts, scraps, and

wounds without the need to apply it topically.

Can Chlorella Be Given To Children?

Absolutely. In fact, chlorella has been shown to promote rapid growth

in children, as well as build in them superior immune systems. In

studies with identical twins, the one given the chlorella grew much

faster, much healthier and had much fewer instances of colds, flu,

etc. than the twin who was not given chlorella. Children can take

one-half to one-fourth the adult dose described above.

Chlorella Scientific Research

Chlorella is one of the MOST scientifically researched foods in human

history. There are thousands of research papers on Chlorella from

medical institutions, scientific journals and universities. NASA has

determined will one of the first foods grown on the space station when

it is completed. The research done on both of these has come from all

over the world by scientists at universities, private industry and

chlorella manufacturers themselves. Not a single negative aspect of

Chlorella has ever been sited as far as human health is concerned.

Below are some representative literature references to reassure you of

chlorella's thoroughly researched benefits and safety:

Performance of different microalgael species in removing nickel and

zinc from industrial wastewater.

Chong AM, Wong YS

Tam Chemosphere. 2000 Jul;41(1-2):251-7

Experiments were conducted to compare the ability of 11 microgaeal

species in removing nickel and zinc from waste water and found them to

be very effective.

Nutritional supplementation with Chlorella pyrenoidosa for patients

with fibromyalgia syndrome: a pilot study.

Merchant RE; Carmack CA; Wise CM

Departments of Anatomy and Internal Medicine, Virginia Commonwealth

University, Medical College of Virginia Richmond, VA 23298-0709, USA.

rmerchan@...

Phytother Res 2000 May;14(3):167-73

Each day for 2 months 20 participants consumed 10 grams (10,000 mg) of

chlorella. Any amelioration of symptoms was validated and quantified

using semi-objective and subjective outcome measures systematically

administered at clinic visits on days 0, 30 and 60 of the diet

therapy. Eighteen of the 20 patients enrolled completed the 2 month

trial. After two months the average pain decrease was 22%.This

decrease was statistically significant. Blood samples taken on each

occasion indicated no significant alterations in serum chemistries,

formed elements, and circulating lymphocyte subsets.

Inhibitory potential of Chlorella vulgaris on mouse skin

papillomagenesis and xenobiotic detoxication system.

Singh A; Singh SP; Bamezai R

Anticancer Res 1999 May-Jun;19(3A):1887-91

The present study assesses the potential of Chlorella vulgaris on

mouse skin cancers, and the role of xenobiotic detoxication system in

modulating the cancer pattern. Topical application of chlorella during

peri-, post- or peri- and post-initiational stages of cancer induction

agents, significantly reduced the cancers. Chlorella treatment alone

or during peri-, post- or peri- and post-initiational stages

significantly elevated the sulfhydryl (-SH) and glutathione

S-transferase (GST) levels in the liver and skin tissues. The results

suggest that topically applied chlorella can prevent skin cancers. The

possible significance of xenobiotic detoxication system in modulating

the cancer pattern is discussed.

Oral administration of a unicellular green algae, Chlorella vulgaris,

prevents stress-induced ulcer.

Tanaka K, Yamada A, Noda K, et al

Planta Med 1997 Oct;63(5):465-6.

Oral administration of dry powder of Chlorella vulgaris showed clear

prophylactic effects in ulcers. Chlorella may prevent ulcer formation

mainly through the " immune-brain-gut " axis and protection of gastric

mucosa by its own characteristics.

Bioregeneration with maltose excreting Chlorella: system concept,

technological development, and experiments.

Wolf L

Adv Space Biol Med 1997;6:255-74

The European Space Agency in the Netherlands studied a small-scale

bioregenerative system to support long-term biological experiments

on-board spacecraft with oxygen, water and food. Core component of

this system were a special photo-bioreactor in which a

maltose-producing strain of the green micro alga Chlorella is cultivated.

Post-exposure radioprotection by Chlorella vulgaris (E-25) in mice.

Singh SP; Tiku AB; Kesavan PC

Indian J Exp Biol 1995 Aug;33(8):612-5

Oral administration of chlorella, 1 hr before or immediately after

exposure to sublethal gamma-rays increased the number of endogenous

spleen colony forming units. The magnitude of radioprotection was

dependent on both, the dose of chlorella fed and the time of

administration. An optimal result was observed when 500 mg/kg body wt.

of C. vulgaris was fed 1 hr before or immediately after irradiation.

Evaluation of radioprotective action of a mutant (E-25) form of

Chlorella vulgaris in mice.

Sarma L; Tiku AB; Kesavan PC; Ogaki M

J Radiat Res (Tokyo) 1993 Dec;34(4):277-84

Investigators examined the role of orally fed Chlorella vulgaris in

modulating the gamma-ray induced chromosomal damage in whole-body

irradiated mice. A significant protection from radiation was observed

in both acute and chronic pretreatments.

Evaluation of radioprotective action of a mutant (E-25) form of

Chlorella vulgaris in mice.

Sarma L; Tiku AB; Kesavan PC; Ogaki M

J Radiat Res (Tokyo) 1993 DEC;34(4):277-84

The possible role of orally fed chlorella in modulating the gamma-ray

induced chromosomal damage in whole-body irradiated mice was

evaluated. Different doses of chlorella were administered either

chronically (once, twice or thrice a day for 28 days) or as single

acute doses before/after irradiation. A significant radiation

protective effect was observed in both acute and chronic

pretreatments, but only at doses above 400 mg/kg body weight.

Microalgae as food and supplement.

Kay RA

Crit Rev Food Sci Nutr 1991;30(6):555-73.

The microalgae Chlorella and the cyanobacteria Spirulina green blue

algae, are being used as nutrient-dense foods and sources of fine

chemicals. They have significant amounts of lipid, protein,

chlorophyll, carotenoids, vitamins, minerals, and unique pigments.

They may also have potent probiotic compounds that enhance health.

Their historical and current use are reviewed in this article.

Effect of chlorella on rats with iron deficient anemia.

Matsuura E; Nemoto T; Hozumi H, et al

Kitasato Arch Exp Med 1991 DEC;64(4):193-204

In order to determine effects of iron deficiency on the living body,

rats were given the iron deficient diet, the complete diet added with

iron, the diet added with 1% chlorella, the diet added with 5%

chlorella, or the diet added with 10% chlorella. For the first 30

days, rats of all groups were given the iron deficiency diet to make

them iron deficient, and were subsequently given the respective diet

during the next 30 days to observe various changes in the conditions

of rats. Following results were obtained. Rats with some chlorella fed

with the diets containing certain amounts of iron rapidly recovered.

Enhanced resistance against Escherichia coli infection by subcutaneous

administration of the hot-water extract of Chlorella vulgaris in

cyclophosphamide-treated mice.

Konishi F; Tanaka K; Kumamoto S, et al

Cancer Immunol Immunother 1990;32(1):1-7

The effects of chlorella vulgaris on the recovery of leukocyte number

and the increase of resistance to bacterial infection were examined in

mice made white cell deficient by cyclophosphamide, an chemotherapy

agent. They were given chlorella (50 mg/kg) subcutaneously under the

skin, every other day from day 1 to day 13 after cyclophosphamide

treatment. Chlorella accelerated the recovery of white blood cells in

the mice. The number of pro white blood cells in the spleen increased

rapidly and highly after the administration of chlorella. Mice given

chlorella showed an enhanced resistance against E. coli infection,

irrespective of the timing of challenge. The bacterial number in

cyclophophamide treated mice increased explosively after inoculation,

resulting in death within 24 h. A progressive elimination of bacteria

was observed from 6 h in the peritoneal cavity, spleen and liver of

cyclophosphamide-treated mice given chlorella. These results indicate

that chlorella can be used as a potent stimulant of nonspecific

resistance to infection in neutropenic mice.

Effect of Chlorella vulgaris extracts on murine cytomegalovirus

infections.

Ibusuki K; Minamishima Y

Nat Immun Cell Growth Regul 1990;9(2):121-8

The host-mediated antiviral effect of chlorella was evaluated in mice

against murine cytomegalovirus (MCMV) infection. Mice treated with 10

mg of chlorella days 3 and 1 before virus challenge survived lethal

infection. The protective effect of chlorella was shown by a decrease

in the infectious viruses replicated in the target organs of

chlorella-treated mice. Chlorella also protected mice from

pathological damage to the target organs due to MCMV infection.

The radioprotective effects of aqueous extract from chlorococcal

freshwater algae (Chlorella kessleri) in mice and rats.

Rotkovska D; Vacek A; Bartonickova A

Strahlenther Onkol 1989 Nov;165(11):813-6

In experiments on mice and rats, the effect was studied of a single

administration of chlorella growth. After injection of this substance

the number of haemopoietic stem cells in the bone marrow and spleen of

mice (CFUs) increased, as did their survival after irradiation.

Irradiation with a lethal dose of gamma rays 24 hours after the

injection of Ivastimul is survived by a larger number of treated mice

and rats than untreated ones. On the first day after the

administration Ivastimul protects mice against brief and prolonged

action of irradiation. The protective effect of Ivastimul was observed

after intraperitoneal, intramuscular and subcutaneous administration.

Effect of dried, powdered Chlorella vulgaris on experimental

atherosclerosis and alimentary hypercholesterolemia in cholesterol-fed

rabbits.

Sano T; Tanaka Y

Artery 1987;14(2):76-84

The anti-lipidemic action and anti-atherosclerotic action of dried,

powdered chlorella was investigated using male Japanese White rabbits.

A ten-week load of high-cholesterol diet remarkably increased serum

total cholesterol and the beta-lipoprotein cholesterol levels in

serum, causing aortic atheromatous lesion. In the Chlorella group

which was administered a high-cholesterol diet containing 1% powdered

chlorella, increase of total and beta-lipoprotein cholesterol level

was suppressed. Further, the development of aortic atheromatous

lesions was significantly inhibited. Clofibrate used as positive

control in this experiment, did not show any inhibitory effect, either

on the increase in serum lipid level or on the development of aortic

atheromatous lesion.

Protective effect of Chlorella on the hepatic damage induced by

ethionine in rats.

Wang LF; Lin JK; Tung YC

Taiwan I Hsueh Hui Tsa Chih 1979 DEC;78(12):1010-9

Chlorella Growth Factor

Effect of hot water extract of Chlorella vulgaris on cytokine

expression patterns in mice with murine acquired immunodeficiency

syndrome after infection with Listeria monocytogenes.

Hasegawa T, Kimura Y, Hiromatsu K, et al

Immunopharmacology. 1997 Jan;35(3):273-82

Oral administration of chlorella growth factor enhances resistance to

Listeria monocytogenes through an increase of Listeria-specific

cell-mediated immunity in normal mice and mice with mice AIDS. To

uncover the mechanisms whereby chlorella increases the cell-mediated

immunity, we examined the expression patterns of mRNA for cytokines in

normal and MAIDS mice given CVE orally after L. monocytogenes

infection. The expression levels of IL-1 alpha, IL-12, GM-CSF, MIP and

TNF alpha genes were significantly augmented in the peritoneal cells

by oral administration of chlorella for 2 weeks before Listeria

infection. In mice infected with AIDS, oral administration of

chlorella also increased the expression of gamma IFN and IL-12 mRNA in

the spleen after Listeria infection, while it rather reduced the

expression of IL-10 mRNA. These results suggest that chlorella may

preferentially augment THI responses against Listeria via activation

of macrophages to produce IL-12 and enhance host defense against

Listeria infection both in normal and MAIDS mice.

Inhibitory effects of sterols isolated from Chlorella vulgaris on

12-0-tetradecanoylphorbol-13-acetate-induced inflammation and tumor

promotion in mouse skin.

Yasukawa K; Akihisa T; Kanno H, et al

Biol Pharm Bull 1996 Apr;19(4):573-6

Inhibitory activity against cancer induced inflammation in mice was

observed in the extract of chlorella that has chlorella growth factor.

Hot water extracts of Chlorella vulgaris reduce opportunistic

infection with Listeria monocytogenes in C57BL/6 mice infected with

LP-BM5 murine leukemia viruses.

Hasegawa T; Okuda M; Makino M, et al

Int J Immunopharmacol 1995 Jun;17(6):505-12

The bacterial elimination after infection with Listeria monocytogenes

was impaired in mice with murine acquired immunodeficiency syndrome

(MAIDS). Oral administration of chlorella growth factor restored the

capacity of mice with AIDS mice to eliminate L. monocytogenes.

Chlorella appears to be effective in the treatment of opportunistic

infection in retrovirus-induced immunodeficient patients.

Augmentation of the resistance against Escherichia coli by oral

administration of a hot water extract of Chlorella vulgaris in rats.

Hasegawa T; Tanaka K; Ueno K, et al

Int J Immunopharmacol 1989;11(8):971-6

In previous studies, we demonstrated that chlorella growth factor

improved the resistance against an intraperitoneal infection with

Escherichia coli by its intraperitoneal, intravenous or subcutaneous

administration. The improved resistance appeared to be attributable to

the enhanced activity of white blood cells. In this study, the effect

of oral administration of chlorella against Escherichia coli infection

was examined. Male rats were administered 1000 mg/kg of chlorella

orally for 14 days and challenged with 2.7 x 10(8) Escherichia coli

intraperitoneally. The numbers of living bacteria in the peritoneal

cavity, blood, spleen and liver at 1, 6, and 24 h after the

inoculation were counted. The bacterial numbers increased during 1-6 h

and reached the peak at 6 h in both control and chlorella administered

groups. The bacterial numbers decreased to an undetectable level at 24

h in both groups. In a chlorella administered group, the numbers of

viable bacteria in each organ were remarkably lower than those in a

control group in all organs so far tested. These results form the

basis for the judgment that the degree of effectiveness of bacteria

clearance from the peritoneal cavity shown by oral chlorella

administration may be strong enough to warrant developing this

material as a new type of biological response modifier.

Augmentation of host defense by a unicellular green alga, Chlorella

vulgaris, to Escherichia coli infection.

Tanaka K; Koga T; Konishi F

Infect Immun 1986 Aug;53(2):267-71

Protection against Escherichia coli inoculated intraperitoneally into

mice was enhanced by intraperitoneal, intravenous, or subcutaneous

administration of chlorella growth factor. The enhancing effect was

detected with doses over 2.0 mg/kg and when doses were administered 1,

4, or 7 days before the infection. The elimination of bacteria from

the spleen of chlorella growth factor treated mice was increased, and

this enhanced elimination may have been related to the acceleration of

superoxide generation and chemokinesis in polymorphonuclear leucocytes

by chlorella growth factor treatment.

Antitumor effect induced by a hot water extract of Chlorella vulgaris

(CE): resistance to Meth-A tumor growth mediated by CE-induced

polymorphonuclear leukocytes.

Konishi F; Tanaka K; Himeno K, et al

Cancer Immunol Immunother 1985;19(2):73-8

When chlorella growth factor was injected into the peritoneal cavity

of mice inoculated with tumor cells, the survival times were

strikingly prolonged. Furthermore, peritoneal exudate cells (PEC) rich

in white blood cells obtained from normal mice 24 h after chlorella

growth factor injection exhibited an antitumor effect in a assay using

normal recipients. It was suggested that chlorella growth factor

induced PEC, presumably white blood cell, expressed an antitumor

effect in cooperation with a host- or recipient-derived element(s)

sensitive to irradiation. The antitumor mechanism of chlorella growth

factor may be one of the biological response modifiers.

Augmentation of antitumor resistance by a strain of unicellular green

algae, Chlorella vulgaris.

Tanaka K; Konishi F; Himeno K, et al

Cancer Immunol Immunother 1984;17(2):90-4

Growth of tumor in mice was inhibited significantly by injection of

chlorella growth factor into the tumor or into the subcutaneous tissue

near the tumor. The augmentation of resistance by chlorella growth

factor may require the participation of T cells and macrophages, since

it was abolished or reduced in athymic nude mice or mice treated with

carrageenan, a macrophage blocker. Mice treated with chlorella growth

factor exhibited antigen-specific augmented resistance against

rechallenge with tumor.

Anti Cancer

A water-soluble antitumor glycoprotein from Chlorella vulgaris.

Noda K; Ohno N; Tanaka K, et al

Planta Med 1996 Oct;62(5):423-6

An active substance with antitumor activity (ARS2) was purified from

the culture media of Chlorella vulgaris and found to be a glycoprotein

with a molecular weight of 63,100 amu, as determined by

matrix-assisted laser desorption/ ionization (MALDI) mass

spectrometry. ARS2 contains 66.9% carbohydrate, mainly D-galactose,

and 35.2% protein. The carbohydrate moiety has a

beta-1,6-D-galactopyranose backbone, as determined by methylation

analysis and 13C-NMR. Apparently, the protein moiety, whose 15 amino

acid sequence at the NH2-terminus, we determined as DVGEAFPTVVDALVA,

is necessary for the antitumor activity, as assessed by

hydrazinolysis, periodate oxidation, and proteolysis.

Protective effect of an acidic glycoprotein obtained from culture of

Chlorella vulgaris against myelosuppression by 5-fluorouracil.

Konishi F; Mitsuyama M; Okuda M, et al

Cancer Immunol Immunother 1996 Jun;42(5):268-74

A protein prepared from a culture of chlorella was examined for its

protective effect on chemotherapy-induced bone marrow suppression and

infections in mice. Subcutaneous administration of chlorella greatly

reduced the mortality of non-tumor-bearing mice given a high dose of

chemotherapy agent 5FU, and could increase the LD50 value of 5FU for

these mice. After 5FU treatment, infections developed probably as a

result of the impairment of the host defense system. Chlorella reduced

the incidence of infections and this effect was attributable to the

acceleration of recovery from 5FU-induced bone marrow suppression.

When tumor-bearing mice were given chlorella during treatment with

5FU, chlorella prolonged the survival of mice without affecting the

antitumor activity of 5FU. In addition, chlorella was itself shown to

exert an antitumor effect. These results suggested that chlorella may

be beneficial for the reduction of side-effects in cancer chemotherapy

without affecting the antitumor activity of the chemotherapeutic agent.

Oral administration of Chlorella vulgaris augments concomitant

antitumor immunity.

Tanaka K; Tomita Y; Tsuruta M, et al

Immunopharmacol Immunotoxicol 1990;12(2):277-91

Chlorella or chlorella factor extract were administered orally to

tumor bearing mice. When two mice were fed daily with 10% dried powder

of chlorella containing diet before and after tumor inoculation, the

growth of rechallenged tumor was significantly suppressed in an

antigen-specific manner.

Inhibitory effects of sterols isolated from Chlorella vulgaris on

12-0-tetradecanoylphorbol-13-acetate-induced inflammation and tumor

promotion in mouse skin.

Yasukawa K; Akihisa T; Kanno H, et al

Biol Pharm Bull 1996 APR;19(4):573-6